In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer

The effects of oxide interlayer on cobalt-chromium-molybdenum substrate were investigated in order to improve the quality of hydroxyapatite (HA) coating as well as enhance the cell responses. Substrates were oxidized at temperature of 850 °C and 1050 °C for 3 hours. Oxidized substrates were then coa...

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Main Authors:	Mas Ayu, Hassan, R., Daud, Sudin, Izman, Arman Shah, Abdullah, Mahmood, Anwar, Krishnamurithy, G., Tunku, Kamarul
Format:	Article
Language:	English
Published:	Penerbit Universiti Teknologi Malaysia 2018
Subjects:	TJ Mechanical engineering and machinery
Online Access:	http://umpir.ump.edu.my/id/eprint/24040/ http://umpir.ump.edu.my/id/eprint/24040/ http://umpir.ump.edu.my/id/eprint/24040/ http://umpir.ump.edu.my/id/eprint/24040/1/In-vitro%20biocompatibility%20study%20of%20hydroxyapatite%20coated%20on%20Co-Cr-Mo%20with%20oxide%20interlayer.pdf

id	ump-24040
recordtype	eprints
spelling	ump-240402019-03-12T02:34:04Z http://umpir.ump.edu.my/id/eprint/24040/ In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer Mas Ayu, Hassan R., Daud Sudin, Izman Arman Shah, Abdullah Mahmood, Anwar Krishnamurithy, G. Tunku, Kamarul TJ Mechanical engineering and machinery The effects of oxide interlayer on cobalt-chromium-molybdenum substrate were investigated in order to improve the quality of hydroxyapatite (HA) coating as well as enhance the cell responses. Substrates were oxidized at temperature of 850 °C and 1050 °C for 3 hours. Oxidized substrates were then coated with HA slurry using dip coating technique. Analysis of surface morphology, thickness and chemical composition of oxide interlayer prior to HA coating were performed using field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy and grazing X-ray diffraction respectively. It seems that rough surface of oxide interlayer provides better mechanical interlocking of HA particles to the substrate surface with no visible micro-cracks. In addition, the HA coated substrates with oxide interlayer also demonstrate strong attachment and better proliferation of cells compared to HA coated substrates without oxide interlayer. The results also demonstrates that cells were spread out more actively as earlier as day 7 and have greater extensions of filopodium on HA coated substrates with oxide interlayer. It is concluded that the introduction of an intermediate oxide layer on Co-Cr-Mo substrate prior to HA coating has shown a positive effect in terms of improving the quality of HA coating as well as cell bioactivity performance. Penerbit Universiti Teknologi Malaysia 2018-01-01 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/24040/1/In-vitro%20biocompatibility%20study%20of%20hydroxyapatite%20coated%20on%20Co-Cr-Mo%20with%20oxide%20interlayer.pdf Mas Ayu, Hassan and R., Daud and Sudin, Izman and Arman Shah, Abdullah and Mahmood, Anwar and Krishnamurithy, G. and Tunku, Kamarul (2018) In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer. Jurnal Teknologi (Sciences and Engineering), 80 (1). pp. 35-42. ISSN 0127-9696 (print); 2180-3722 (online) https://doi.org/10.11113/jt.v80.10368 https://doi.org/10.11113/jt.v80.10368
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TJ Mechanical engineering and machinery
spellingShingle	TJ Mechanical engineering and machinery Mas Ayu, Hassan R., Daud Sudin, Izman Arman Shah, Abdullah Mahmood, Anwar Krishnamurithy, G. Tunku, Kamarul In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer
description	The effects of oxide interlayer on cobalt-chromium-molybdenum substrate were investigated in order to improve the quality of hydroxyapatite (HA) coating as well as enhance the cell responses. Substrates were oxidized at temperature of 850 °C and 1050 °C for 3 hours. Oxidized substrates were then coated with HA slurry using dip coating technique. Analysis of surface morphology, thickness and chemical composition of oxide interlayer prior to HA coating were performed using field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy and grazing X-ray diffraction respectively. It seems that rough surface of oxide interlayer provides better mechanical interlocking of HA particles to the substrate surface with no visible micro-cracks. In addition, the HA coated substrates with oxide interlayer also demonstrate strong attachment and better proliferation of cells compared to HA coated substrates without oxide interlayer. The results also demonstrates that cells were spread out more actively as earlier as day 7 and have greater extensions of filopodium on HA coated substrates with oxide interlayer. It is concluded that the introduction of an intermediate oxide layer on Co-Cr-Mo substrate prior to HA coating has shown a positive effect in terms of improving the quality of HA coating as well as cell bioactivity performance.
format	Article
author	Mas Ayu, Hassan R., Daud Sudin, Izman Arman Shah, Abdullah Mahmood, Anwar Krishnamurithy, G. Tunku, Kamarul
author_facet	Mas Ayu, Hassan R., Daud Sudin, Izman Arman Shah, Abdullah Mahmood, Anwar Krishnamurithy, G. Tunku, Kamarul
author_sort	Mas Ayu, Hassan
title	In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer
title_short	In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer
title_full	In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer
title_fullStr	In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer
title_full_unstemmed	In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer
title_sort	in-vitro biocompatibility study of hydroxyapatite coated on co-cr-mo with oxide interlayer
publisher	Penerbit Universiti Teknologi Malaysia
publishDate	2018
url	http://umpir.ump.edu.my/id/eprint/24040/ http://umpir.ump.edu.my/id/eprint/24040/ http://umpir.ump.edu.my/id/eprint/24040/ http://umpir.ump.edu.my/id/eprint/24040/1/In-vitro%20biocompatibility%20study%20of%20hydroxyapatite%20coated%20on%20Co-Cr-Mo%20with%20oxide%20interlayer.pdf
first_indexed	2023-09-18T22:36:12Z
last_indexed	2023-09-18T22:36:12Z
_version_	1777416612429692928

In-vitro biocompatibility study of hydroxyapatite coated on Co-Cr-Mo with oxide interlayer

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