Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract

Electrospun nanofibers were prepared from Rhodomyrtus tomentosa extract and poly(vinyl alcohol). The antimicrobial effect was assessed against two Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa) and two Gram-positive bacterial strains (Bacillus subtilis, Enteroco...

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Main Authors:	Senait, Sileshi Zeyohanness, Hazrulrizawati, Hamid, Farah Hanani, Zulkifli
Format:	Article
Language:	English
Published:	Sage 2018
Subjects:	QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/23909/ http://umpir.ump.edu.my/id/eprint/23909/ http://umpir.ump.edu.my/id/eprint/23909/ http://umpir.ump.edu.my/id/eprint/23909/1/Poly%28vinyl%20alcohol%29%20electrospun1.pdf

id	ump-23909
recordtype	eprints
spelling	ump-239092019-01-25T01:52:23Z http://umpir.ump.edu.my/id/eprint/23909/ Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract Senait, Sileshi Zeyohanness Hazrulrizawati, Hamid Farah Hanani, Zulkifli QD Chemistry Electrospun nanofibers were prepared from Rhodomyrtus tomentosa extract and poly(vinyl alcohol). The antimicrobial effect was assessed against two Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa) and two Gram-positive bacterial strains (Bacillus subtilis, Enterococcus faecalis) by paper disc diffusion method. Ethyl acetate extract of R. tomentosawas selected for fabrication of nanofibers because it shows the most active antimicrobial activity with zone of inhibition ranging from 9.33 ±0.21 to 13.67 ± 0.32 mm. The presence of high abundance of myricetin and rhodomyrtone might contribute to the antibiotic activity against all tested bacterial strains. The average diameter of the R. tomentosa extract/poly(vinyl alcohol) nanofibers increased from 120.4 to 214.8 nm with increasing concentration of R. tomentosaextract from 0.5% to 2.5%. The antimicrobial activity of R. tomentosa extract/poly(vinyl alcohol) nanofibers was relatively higher at concentration of the extract (1.5% and 2.5%) against all test organisms with a clear zone of inhibition 7–12 mm. The results demonstrated that R. tomentosa extract/poly(vinyl alcohol) electrospun nanofibers are an interesting platform for delivery of bioactive compounds as wound dressing or other strategies for combating bacterial infections. Sage 2018-11 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23909/1/Poly%28vinyl%20alcohol%29%20electrospun1.pdf Senait, Sileshi Zeyohanness and Hazrulrizawati, Hamid and Farah Hanani, Zulkifli (2018) Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract. Journal of Bioactive and Compatible Polymers, 33 (6). pp. 585-596. ISSN 1530-8030 https://doi.org/10.1177%2F0883911518801040 https://doi.org/10.1177%2F0883911518801040
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Senait, Sileshi Zeyohanness Hazrulrizawati, Hamid Farah Hanani, Zulkifli Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract
description	Electrospun nanofibers were prepared from Rhodomyrtus tomentosa extract and poly(vinyl alcohol). The antimicrobial effect was assessed against two Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa) and two Gram-positive bacterial strains (Bacillus subtilis, Enterococcus faecalis) by paper disc diffusion method. Ethyl acetate extract of R. tomentosawas selected for fabrication of nanofibers because it shows the most active antimicrobial activity with zone of inhibition ranging from 9.33 ±0.21 to 13.67 ± 0.32 mm. The presence of high abundance of myricetin and rhodomyrtone might contribute to the antibiotic activity against all tested bacterial strains. The average diameter of the R. tomentosa extract/poly(vinyl alcohol) nanofibers increased from 120.4 to 214.8 nm with increasing concentration of R. tomentosaextract from 0.5% to 2.5%. The antimicrobial activity of R. tomentosa extract/poly(vinyl alcohol) nanofibers was relatively higher at concentration of the extract (1.5% and 2.5%) against all test organisms with a clear zone of inhibition 7–12 mm. The results demonstrated that R. tomentosa extract/poly(vinyl alcohol) electrospun nanofibers are an interesting platform for delivery of bioactive compounds as wound dressing or other strategies for combating bacterial infections.
format	Article
author	Senait, Sileshi Zeyohanness Hazrulrizawati, Hamid Farah Hanani, Zulkifli
author_facet	Senait, Sileshi Zeyohanness Hazrulrizawati, Hamid Farah Hanani, Zulkifli
author_sort	Senait, Sileshi Zeyohanness
title	Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract
title_short	Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract
title_full	Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract
title_fullStr	Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract
title_full_unstemmed	Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract
title_sort	poly(vinyl alcohol) electrospun nanofibers containing antimicrobial rhodomyrtus tomentosa extract
publisher	Sage
publishDate	2018
url	http://umpir.ump.edu.my/id/eprint/23909/ http://umpir.ump.edu.my/id/eprint/23909/ http://umpir.ump.edu.my/id/eprint/23909/ http://umpir.ump.edu.my/id/eprint/23909/1/Poly%28vinyl%20alcohol%29%20electrospun1.pdf
first_indexed	2023-09-18T22:36:01Z
last_indexed	2023-09-18T22:36:01Z
_version_	1777416600430837760

Poly(vinyl alcohol) electrospun nanofibers containing antimicrobial Rhodomyrtus tomentosa extract

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