Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity

Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity

Recently, discovering natural antioxidants have gained more interest due to the fact that most infectious ailment, namely cardiovascular disorder, diabetes and cancer are associated with free radical cells. Thus, the extraction of phenolic compounds from Vernonia cinerea leaves through Soxhlet extra...

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Main Authors: Alara, Oluwaseun Ruth, Nour, A. H., Ukaegbu, Chinonso Ishmael
Format: Article
Language:English
Published: Elsevier GmbH 2018
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://umpir.ump.edu.my/id/eprint/23758/
http://umpir.ump.edu.my/id/eprint/23758/
http://umpir.ump.edu.my/id/eprint/23758/
http://umpir.ump.edu.my/id/eprint/23758/1/Soxhlet%20extraction%20of%20phenolic%20compounds%20from%20Vernonia%20cinerea.pdf
id ump-23758
recordtype eprints
spelling ump-237582020-02-28T08:10:38Z http://umpir.ump.edu.my/id/eprint/23758/ Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity Alara, Oluwaseun Ruth Nour, A. H. Ukaegbu, Chinonso Ishmael TJ Mechanical engineering and machinery Recently, discovering natural antioxidants have gained more interest due to the fact that most infectious ailment, namely cardiovascular disorder, diabetes and cancer are associated with free radical cells. Thus, the extraction of phenolic compounds from Vernonia cinerea leaves through Soxhlet extraction method was studied. The effects of extraction time (1–4 h), feed-to-solvent (1:10–1:25 g/mL) and ethanol concentration (20–80% v/v) on the yield of extract, total phenolic content (TPC) and total flavonoid content (TFC) were examined. Moreover, the phenolic compounds and functional groups in the extract at maximum conditions were identified using Liquid Chromatography-Mass Spectrometry Quadrupole Time of Flight (LC–Q–TOF–MS) and Fourier Transform Infrared Spectrometry (FTIR), respectively. The antioxidant activity of the extract was as well investigated. The experimental results showed that the highest yield of extract (10.01 ± 0.85% w/w), TPC (53.96 ± 1.45 mg GAE/g d.w.) and TFC (30.09 ± 0.44 mg QE/g d.w.) were achieved using extraction time of 2 h, feed-to-solvent of 1:20 g/mL and ethanol concentration of 60% v/v. However, the extract reflected good antioxidant activity. Elsevier GmbH 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23758/1/Soxhlet%20extraction%20of%20phenolic%20compounds%20from%20Vernonia%20cinerea.pdf Alara, Oluwaseun Ruth and Nour, A. H. and Ukaegbu, Chinonso Ishmael (2018) Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity. Journal of Applied Research on Medicinal and Aromatic Plants, 11. pp. 12-17. ISSN 2214-7861 https://doi.org/10.1016/j.jarmap.2018.07.003 https://doi.org/10.1016/j.jarmap.2018.07.003
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Alara, Oluwaseun Ruth
Nour, A. H.
Ukaegbu, Chinonso Ishmael
Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity
description Recently, discovering natural antioxidants have gained more interest due to the fact that most infectious ailment, namely cardiovascular disorder, diabetes and cancer are associated with free radical cells. Thus, the extraction of phenolic compounds from Vernonia cinerea leaves through Soxhlet extraction method was studied. The effects of extraction time (1–4 h), feed-to-solvent (1:10–1:25 g/mL) and ethanol concentration (20–80% v/v) on the yield of extract, total phenolic content (TPC) and total flavonoid content (TFC) were examined. Moreover, the phenolic compounds and functional groups in the extract at maximum conditions were identified using Liquid Chromatography-Mass Spectrometry Quadrupole Time of Flight (LC–Q–TOF–MS) and Fourier Transform Infrared Spectrometry (FTIR), respectively. The antioxidant activity of the extract was as well investigated. The experimental results showed that the highest yield of extract (10.01 ± 0.85% w/w), TPC (53.96 ± 1.45 mg GAE/g d.w.) and TFC (30.09 ± 0.44 mg QE/g d.w.) were achieved using extraction time of 2 h, feed-to-solvent of 1:20 g/mL and ethanol concentration of 60% v/v. However, the extract reflected good antioxidant activity.
format Article
author Alara, Oluwaseun Ruth
Nour, A. H.
Ukaegbu, Chinonso Ishmael
author_facet Alara, Oluwaseun Ruth
Nour, A. H.
Ukaegbu, Chinonso Ishmael
author_sort Alara, Oluwaseun Ruth
title Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity
title_short Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity
title_full Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity
title_fullStr Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity
title_full_unstemmed Soxhlet extraction of Phenolic Compounds from Vernonia cinerea leaves ant its antioxidant activity
title_sort soxhlet extraction of phenolic compounds from vernonia cinerea leaves ant its antioxidant activity
publisher Elsevier GmbH
publishDate 2018
url http://umpir.ump.edu.my/id/eprint/23758/
http://umpir.ump.edu.my/id/eprint/23758/
http://umpir.ump.edu.my/id/eprint/23758/
http://umpir.ump.edu.my/id/eprint/23758/1/Soxhlet%20extraction%20of%20phenolic%20compounds%20from%20Vernonia%20cinerea.pdf
first_indexed 2023-09-18T22:35:43Z
last_indexed 2023-09-18T22:35:43Z
_version_ 1777416581880479744

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