Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves

Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves

Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic c...

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Main Authors: Alara, Oluwaseun Ruth, Nour, A. H., Siti Kholijah, Abdul Mudalip, Ukaegbu, Chinonso Ishmael, Azhari, H. Nour, Kabbashi, Nassereldeen Ahmed
Format: Conference or Workshop Item
Language:English
Published: Universiti Malaysia Pahang 2018
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/23089/
http://umpir.ump.edu.my/id/eprint/23089/
http://umpir.ump.edu.my/id/eprint/23089/1/Parametric%20Study%20of%20Soxhlet%20Extraction.pdf
id ump-23089
recordtype eprints
spelling ump-230892020-02-28T08:12:09Z http://umpir.ump.edu.my/id/eprint/23089/ Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed TP Chemical technology Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then, the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, 214 National Conference for Postgraduate Research (NCON-PGR) six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters. Universiti Malaysia Pahang 2018-08 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23089/1/Parametric%20Study%20of%20Soxhlet%20Extraction.pdf Alara, Oluwaseun Ruth and Nour, A. H. and Siti Kholijah, Abdul Mudalip and Ukaegbu, Chinonso Ishmael and Azhari, H. Nour and Kabbashi, Nassereldeen Ahmed (2018) Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves. In: Proceedings Book: National Conference for Postgraduate Research (NCON-PGR 2018), 28-29 August 2018 , Universiti Malaysia Pahang, Gambang, Pahang. pp. 213-219.. ISBN 978-967-22260-5-5 http://ncon-pgr.ump.edu.my/index.php/en/download/proceedings-book/file
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Ukaegbu, Chinonso Ishmael
Azhari, H. Nour
Kabbashi, Nassereldeen Ahmed
Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
description Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then, the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, 214 National Conference for Postgraduate Research (NCON-PGR) six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters.
format Conference or Workshop Item
author Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Ukaegbu, Chinonso Ishmael
Azhari, H. Nour
Kabbashi, Nassereldeen Ahmed
author_facet Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Ukaegbu, Chinonso Ishmael
Azhari, H. Nour
Kabbashi, Nassereldeen Ahmed
author_sort Alara, Oluwaseun Ruth
title Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_short Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_full Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_fullStr Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_full_unstemmed Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
title_sort parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
publisher Universiti Malaysia Pahang
publishDate 2018
url http://umpir.ump.edu.my/id/eprint/23089/
http://umpir.ump.edu.my/id/eprint/23089/
http://umpir.ump.edu.my/id/eprint/23089/1/Parametric%20Study%20of%20Soxhlet%20Extraction.pdf
first_indexed 2023-09-18T22:34:28Z
last_indexed 2023-09-18T22:34:28Z
_version_ 1777416502591356928

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