Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment

Biomedical grade of cobalt based alloy have found a plethora of applications as medical devices especially in dental and articulation joints like in total ankle, knee and hip arthroplasty. However, the long-term performance of this material is highly dependent on their ability to withstand in harsh...

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Main Authors:	Mas Ayu, Hassan, Rosdi, Daud, Sudin, Izman, A., Shah, Mahmood, Anwar, Kurniawan, Tedi, Juliawati, Alias
Format:	Conference or Workshop Item
Language:	English English
Published:	2018
Subjects:	TJ Mechanical engineering and machinery TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/22982/ http://umpir.ump.edu.my/id/eprint/22982/1/101.%20Improving%20biocompatibility%20of%20cobalt%20based%20alloy%20using%20chemical.pdf http://umpir.ump.edu.my/id/eprint/22982/2/101.1%20Improving%20biocompatibility%20of%20cobalt%20based%20alloy%20using%20chemical.pdf

id	ump-22982
recordtype	eprints
spelling	ump-229822019-02-08T08:34:32Z http://umpir.ump.edu.my/id/eprint/22982/ Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment Mas Ayu, Hassan Rosdi, Daud Sudin, Izman A., Shah Mahmood, Anwar Kurniawan, Tedi Juliawati, Alias TJ Mechanical engineering and machinery TP Chemical technology Biomedical grade of cobalt based alloy have found a plethora of applications as medical devices especially in dental and articulation joints like in total ankle, knee and hip arthroplasty. However, the long-term performance of this material is highly dependent on their ability to withstand in harsh aqueous environment effects such as corrosion and wear once they are used inside a human body. Loss of surface integrity and subsequent leaching of toxic metal ions as well as particles to the surrounding tissues may undermine biocompatibility of metallic implants, also potentially causing untimely loss of mechanical function and device failure. In this study, a biomedical grade of Co-Cr-Mo alloy surface was treated with various surface modification techniques such as chemical etching and mechanical roughening in order to improve its biocompatibility. Investigation was done to study which techniques possesses the positive effect in cell growth and excellent cell response on the treated surface of Co-Cr-Mo alloy. In-vitro study showed that human osteoblast cells grown with good adherence and spread out with an intimate contact on the chemical etched surface after 14 days of incubation. It is believed that porous structure with grooves owned by chemical etched surface helps in anchoring the cells to the substrate surface and facilitates cells growth since more protein molecules expected to have more sites on CT surface. On mechanical roughened surface, the cells appeared to show slightly less extended cell membranes and remained rounded. 2018-08 Conference or Workshop Item NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/22982/1/101.%20Improving%20biocompatibility%20of%20cobalt%20based%20alloy%20using%20chemical.pdf pdf en http://umpir.ump.edu.my/id/eprint/22982/2/101.1%20Improving%20biocompatibility%20of%20cobalt%20based%20alloy%20using%20chemical.pdf Mas Ayu, Hassan and Rosdi, Daud and Sudin, Izman and A., Shah and Mahmood, Anwar and Kurniawan, Tedi and Juliawati, Alias (2018) Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment. In: 4th International Conference on Mechanical, Manufacturing and Plant Engineering, 14 - 15 November 2018 , Melaka, Malaysia. pp. 1-6.. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English
topic	TJ Mechanical engineering and machinery TP Chemical technology
spellingShingle	TJ Mechanical engineering and machinery TP Chemical technology Mas Ayu, Hassan Rosdi, Daud Sudin, Izman A., Shah Mahmood, Anwar Kurniawan, Tedi Juliawati, Alias Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
description	Biomedical grade of cobalt based alloy have found a plethora of applications as medical devices especially in dental and articulation joints like in total ankle, knee and hip arthroplasty. However, the long-term performance of this material is highly dependent on their ability to withstand in harsh aqueous environment effects such as corrosion and wear once they are used inside a human body. Loss of surface integrity and subsequent leaching of toxic metal ions as well as particles to the surrounding tissues may undermine biocompatibility of metallic implants, also potentially causing untimely loss of mechanical function and device failure. In this study, a biomedical grade of Co-Cr-Mo alloy surface was treated with various surface modification techniques such as chemical etching and mechanical roughening in order to improve its biocompatibility. Investigation was done to study which techniques possesses the positive effect in cell growth and excellent cell response on the treated surface of Co-Cr-Mo alloy. In-vitro study showed that human osteoblast cells grown with good adherence and spread out with an intimate contact on the chemical etched surface after 14 days of incubation. It is believed that porous structure with grooves owned by chemical etched surface helps in anchoring the cells to the substrate surface and facilitates cells growth since more protein molecules expected to have more sites on CT surface. On mechanical roughened surface, the cells appeared to show slightly less extended cell membranes and remained rounded.
format	Conference or Workshop Item
author	Mas Ayu, Hassan Rosdi, Daud Sudin, Izman A., Shah Mahmood, Anwar Kurniawan, Tedi Juliawati, Alias
author_facet	Mas Ayu, Hassan Rosdi, Daud Sudin, Izman A., Shah Mahmood, Anwar Kurniawan, Tedi Juliawati, Alias
author_sort	Mas Ayu, Hassan
title	Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
title_short	Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
title_full	Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
title_fullStr	Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
title_full_unstemmed	Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
title_sort	improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment
publishDate	2018
url	http://umpir.ump.edu.my/id/eprint/22982/ http://umpir.ump.edu.my/id/eprint/22982/1/101.%20Improving%20biocompatibility%20of%20cobalt%20based%20alloy%20using%20chemical.pdf http://umpir.ump.edu.my/id/eprint/22982/2/101.1%20Improving%20biocompatibility%20of%20cobalt%20based%20alloy%20using%20chemical.pdf
first_indexed	2023-09-18T22:34:14Z
last_indexed	2023-09-18T22:34:14Z
_version_	1777416488165048320

Improving biocompatibility of cobalt based alloy using chemical etching and mechanical treatment

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