Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests

Measuring the accuracy of diagnostic tests is crucial in many application areas including medicine, machine learning and credit scoring. The receiver operating characteristic (ROC) curve is a useful tool to assess the ability of a diagnostic test to discriminate among two classes or groups. In pract...

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Main Authors: Noryanti, Muhammad, Coolen-Maturi, Tahani, Coolen, Frank PA
Format: Article
Language:English
Published: International Academic Press 2018
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Online Access:http://umpir.ump.edu.my/id/eprint/22880/
http://umpir.ump.edu.my/id/eprint/22880/
http://umpir.ump.edu.my/id/eprint/22880/
http://umpir.ump.edu.my/id/eprint/22880/1/SOIC-FC-1708.pdf
id ump-22880
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spelling ump-228802019-01-16T08:21:08Z http://umpir.ump.edu.my/id/eprint/22880/ Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests Noryanti, Muhammad Coolen-Maturi, Tahani Coolen, Frank PA Q Science (General) QA Mathematics Measuring the accuracy of diagnostic tests is crucial in many application areas including medicine, machine learning and credit scoring. The receiver operating characteristic (ROC) curve is a useful tool to assess the ability of a diagnostic test to discriminate among two classes or groups. In practice, multiple diagnostic tests or biomarkers may be combined to improve diagnostic accuracy, e.g. by maximizing the area under the ROC curve. In this paper we present Nonparametric Predictive Inference (NPI) for best linear combination of two biomarkers, where the dependence of the two biomarkers is modelled using parametric copulas. NPI is a frequentist statistical method that is explicitly aimed at using few modelling assumptions, enabled through the use of lower and upper probabilities to quantify uncertainty. The combination of NPI for the individual biomarkers, combined with a basic parametric copula to take dependence into account, has good robustness properties and leads to quite straightforward computation. We briefly comment on the results of a simulation study to investigate the performance of the proposed method in comparison to the empirical method. An example with data from the literature is provided to illustrate the proposed method, and related research problems are briefly discussed. International Academic Press 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/22880/1/SOIC-FC-1708.pdf Noryanti, Muhammad and Coolen-Maturi, Tahani and Coolen, Frank PA (2018) Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests. Statistics, optimization and information computing., 6 (3). pp. 398-408. ISSN 2311-004X http://www.iapress.org/index.php/soic/article/view/soic.20180906/359 https://doi.org//10.19139/soic.v6i3.579
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic Q Science (General)
QA Mathematics
spellingShingle Q Science (General)
QA Mathematics
Noryanti, Muhammad
Coolen-Maturi, Tahani
Coolen, Frank PA
Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
description Measuring the accuracy of diagnostic tests is crucial in many application areas including medicine, machine learning and credit scoring. The receiver operating characteristic (ROC) curve is a useful tool to assess the ability of a diagnostic test to discriminate among two classes or groups. In practice, multiple diagnostic tests or biomarkers may be combined to improve diagnostic accuracy, e.g. by maximizing the area under the ROC curve. In this paper we present Nonparametric Predictive Inference (NPI) for best linear combination of two biomarkers, where the dependence of the two biomarkers is modelled using parametric copulas. NPI is a frequentist statistical method that is explicitly aimed at using few modelling assumptions, enabled through the use of lower and upper probabilities to quantify uncertainty. The combination of NPI for the individual biomarkers, combined with a basic parametric copula to take dependence into account, has good robustness properties and leads to quite straightforward computation. We briefly comment on the results of a simulation study to investigate the performance of the proposed method in comparison to the empirical method. An example with data from the literature is provided to illustrate the proposed method, and related research problems are briefly discussed.
format Article
author Noryanti, Muhammad
Coolen-Maturi, Tahani
Coolen, Frank PA
author_facet Noryanti, Muhammad
Coolen-Maturi, Tahani
Coolen, Frank PA
author_sort Noryanti, Muhammad
title Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
title_short Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
title_full Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
title_fullStr Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
title_full_unstemmed Nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
title_sort nonparametric predictive inference with parametric copulas for combining bivariate diagnostic tests
publisher International Academic Press
publishDate 2018
url http://umpir.ump.edu.my/id/eprint/22880/
http://umpir.ump.edu.my/id/eprint/22880/
http://umpir.ump.edu.my/id/eprint/22880/
http://umpir.ump.edu.my/id/eprint/22880/1/SOIC-FC-1708.pdf
first_indexed 2023-09-18T22:34:01Z
last_indexed 2023-09-18T22:34:01Z
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