Comparative structural analysis of fruit and stem bromelain from Ananas comosus

Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities. Bromelain has been identified as an active component and as a major protease of A. comosus. Bromelain has gained wide...

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Main Authors:	Aizi Nor Mazila, Ramli, Nor Hasmaliana, Abdul Manas, Azzmer Azzar, Abdul Hamid, Hazrulrizawati, Hamid, Rosli Md, Illias
Format:	Article
Language:	English
Published:	Elsevier Ltd 2018
Subjects:	Q Science (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/22280/ http://umpir.ump.edu.my/id/eprint/22280/ http://umpir.ump.edu.my/id/eprint/22280/ http://umpir.ump.edu.my/id/eprint/22280/1/Comparative%20structural%20analysis%20of%20fruit%20and%20stem%20bromelain%20from%20Ananas%20comosus.pdf

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recordtype	eprints
spelling	ump-222802018-10-11T08:45:59Z http://umpir.ump.edu.my/id/eprint/22280/ Comparative structural analysis of fruit and stem bromelain from Ananas comosus Aizi Nor Mazila, Ramli Nor Hasmaliana, Abdul Manas Azzmer Azzar, Abdul Hamid Hazrulrizawati, Hamid Rosli Md, Illias Q Science (General) Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities. Bromelain has been identified as an active component and as a major protease of A. comosus. Bromelain has gained wide acceptance and compliance as a phytotherapeutical drug. The proteolytic fraction of pineapple stem is termed stem bromelain, while the one presents in the fruit is known as fruit bromelain. The amino acid sequence and domain analysis of the fruit and stem bromelains demonstrated several differences and similarities of these cysteine protease family members. In addition, analysis of the modelled fruit (BAA21848) and stem (CAA08861) bromelains revealed the presence of unique properties of the predicted structures. Sequence analysis and structural prediction of stem and fruit bromelains of A. comosus along with the comparison of both structures provides a new insight on their distinct properties for industrial application. Elsevier Ltd 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/22280/1/Comparative%20structural%20analysis%20of%20fruit%20and%20stem%20bromelain%20from%20Ananas%20comosus.pdf Aizi Nor Mazila, Ramli and Nor Hasmaliana, Abdul Manas and Azzmer Azzar, Abdul Hamid and Hazrulrizawati, Hamid and Rosli Md, Illias (2018) Comparative structural analysis of fruit and stem bromelain from Ananas comosus. Food Chemistry, 266. pp. 183-191. ISSN 0308-8146 https://doi.org/10.1016/j.foodchem.2018.05.125 doi: 10.1016/j.foodchem.2018.05.125
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Aizi Nor Mazila, Ramli Nor Hasmaliana, Abdul Manas Azzmer Azzar, Abdul Hamid Hazrulrizawati, Hamid Rosli Md, Illias Comparative structural analysis of fruit and stem bromelain from Ananas comosus
description	Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities. Bromelain has been identified as an active component and as a major protease of A. comosus. Bromelain has gained wide acceptance and compliance as a phytotherapeutical drug. The proteolytic fraction of pineapple stem is termed stem bromelain, while the one presents in the fruit is known as fruit bromelain. The amino acid sequence and domain analysis of the fruit and stem bromelains demonstrated several differences and similarities of these cysteine protease family members. In addition, analysis of the modelled fruit (BAA21848) and stem (CAA08861) bromelains revealed the presence of unique properties of the predicted structures. Sequence analysis and structural prediction of stem and fruit bromelains of A. comosus along with the comparison of both structures provides a new insight on their distinct properties for industrial application.
format	Article
author	Aizi Nor Mazila, Ramli Nor Hasmaliana, Abdul Manas Azzmer Azzar, Abdul Hamid Hazrulrizawati, Hamid Rosli Md, Illias
author_facet	Aizi Nor Mazila, Ramli Nor Hasmaliana, Abdul Manas Azzmer Azzar, Abdul Hamid Hazrulrizawati, Hamid Rosli Md, Illias
author_sort	Aizi Nor Mazila, Ramli
title	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_short	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_full	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_fullStr	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_full_unstemmed	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_sort	comparative structural analysis of fruit and stem bromelain from ananas comosus
publisher	Elsevier Ltd
publishDate	2018
url	http://umpir.ump.edu.my/id/eprint/22280/ http://umpir.ump.edu.my/id/eprint/22280/ http://umpir.ump.edu.my/id/eprint/22280/ http://umpir.ump.edu.my/id/eprint/22280/1/Comparative%20structural%20analysis%20of%20fruit%20and%20stem%20bromelain%20from%20Ananas%20comosus.pdf
first_indexed	2023-09-18T22:33:05Z
last_indexed	2023-09-18T22:33:05Z
_version_	1777416415797575680

Comparative structural analysis of fruit and stem bromelain from Ananas comosus

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