Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves

Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves

Chromolaena odorata (Bitter bush) belongs to the family Asteraceae. It is used as a source of medicine especially in Asia and West Africa countries [1]. Phenolic compounds are mostly distributed group of phytochemicals that possess a wide range of physiological activities like antiinflammatory, anti...

Full description

Bibliographic Details
Main Authors: Alara, Oluwaseun Ruth, Nour, A. H., Siti Kholijah, Abdul Mudalip, Olalere, Olusegun Abayomi
Format: Conference or Workshop Item
Language:English
Published: 2018
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/21931/
http://umpir.ump.edu.my/id/eprint/21931/1/Conference%20Proceeding%20for%20ICCEIB2018%201.pdf
id ump-21931
recordtype eprints
spelling ump-219312019-09-10T06:50:05Z http://umpir.ump.edu.my/id/eprint/21931/ Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Olalere, Olusegun Abayomi TP Chemical technology Chromolaena odorata (Bitter bush) belongs to the family Asteraceae. It is used as a source of medicine especially in Asia and West Africa countries [1]. Phenolic compounds are mostly distributed group of phytochemicals that possess a wide range of physiological activities like antiinflammatory, anti-cancer, vasodilatory effects, antioxidant, and among others [2]. Several phenolic compounds have been extracted and isolated from this plant, including vanillic acid, pcoumaric, protocatechuic, quercetin, luteolin, kaempferol, and among others [3]. The effects of microwave-assisted extraction (MAE) variables on the recovery yields of total phenolic content (TPC) and total flavonoid content (TFC) from Chromolaena odorata leaves were investigated using single factor experiment and two-level factorial design. The examined MAE variables were irradiation time, A (1-5 min), microwave power level, B (400-800 W), temperature, C (60-80 °C), solvent-feed ratio, D (8-14 ml/g) and ethanol concentration, E (20-60%). The obtained results showed that irradiation time (3.90 %), microwave power level (14.93 %) and ethanol concentration (17.21 %) significantly contributed to the recoveries of TPC and TFC from Chromolaena odorata leaves (Fig. 1). This implies that irradiation time, microwave power and ethanol concentration were significant (p < 0.05) in obtaining higher recoveries. Thus, the significant variables will be considered for the optimization process 2018-08-02 Conference or Workshop Item NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/21931/1/Conference%20Proceeding%20for%20ICCEIB2018%201.pdf Alara, Oluwaseun Ruth and Nour, A. H. and Siti Kholijah, Abdul Mudalip and Olalere, Olusegun Abayomi (2018) Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves. In: 4th International Conference Of Chemical Engineering And Industrial Biotechnology (ICCEIB 2018), 1-2 Aug 2018 , Seri Pacific Hotel, Kuala Lumpur. pp. 520-521.. (Unpublished)
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Olalere, Olusegun Abayomi
Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
description Chromolaena odorata (Bitter bush) belongs to the family Asteraceae. It is used as a source of medicine especially in Asia and West Africa countries [1]. Phenolic compounds are mostly distributed group of phytochemicals that possess a wide range of physiological activities like antiinflammatory, anti-cancer, vasodilatory effects, antioxidant, and among others [2]. Several phenolic compounds have been extracted and isolated from this plant, including vanillic acid, pcoumaric, protocatechuic, quercetin, luteolin, kaempferol, and among others [3]. The effects of microwave-assisted extraction (MAE) variables on the recovery yields of total phenolic content (TPC) and total flavonoid content (TFC) from Chromolaena odorata leaves were investigated using single factor experiment and two-level factorial design. The examined MAE variables were irradiation time, A (1-5 min), microwave power level, B (400-800 W), temperature, C (60-80 °C), solvent-feed ratio, D (8-14 ml/g) and ethanol concentration, E (20-60%). The obtained results showed that irradiation time (3.90 %), microwave power level (14.93 %) and ethanol concentration (17.21 %) significantly contributed to the recoveries of TPC and TFC from Chromolaena odorata leaves (Fig. 1). This implies that irradiation time, microwave power and ethanol concentration were significant (p < 0.05) in obtaining higher recoveries. Thus, the significant variables will be considered for the optimization process
format Conference or Workshop Item
author Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Olalere, Olusegun Abayomi
author_facet Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Olalere, Olusegun Abayomi
author_sort Alara, Oluwaseun Ruth
title Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
title_short Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
title_full Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
title_fullStr Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
title_full_unstemmed Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
title_sort two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves
publishDate 2018
url http://umpir.ump.edu.my/id/eprint/21931/
http://umpir.ump.edu.my/id/eprint/21931/1/Conference%20Proceeding%20for%20ICCEIB2018%201.pdf
first_indexed 2023-09-18T22:32:24Z
last_indexed 2023-09-18T22:32:24Z
_version_ 1777416373385822208

Similar Items