Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli

Oscillatory Flow Reactor (OFR) is a novel type of tubular reactor consists of an equally spaced orifice baffles fitted inside the column of the reactor. The mixing in the OFR can be controlled by a combination of geometrical (i.e. baffles and orifice diameter) and operational parameters (i.e. oscill...

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Main Authors:	Norfaezahtul, Nor Azaini, N., Masngut
Format:	Article
Language:	English
Published:	Malaysian Society of Applied Biology 2018
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/21770/ http://umpir.ump.edu.my/id/eprint/21770/ http://umpir.ump.edu.my/id/eprint/21770/1/Characterisation%20of%20the%20Oscillatory%20Flow.pdf

id	ump-21770
recordtype	eprints
spelling	ump-217702018-07-24T08:08:14Z http://umpir.ump.edu.my/id/eprint/21770/ Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli Norfaezahtul, Nor Azaini N., Masngut TP Chemical technology Oscillatory Flow Reactor (OFR) is a novel type of tubular reactor consists of an equally spaced orifice baffles fitted inside the column of the reactor. The mixing in the OFR can be controlled by a combination of geometrical (i.e. baffles and orifice diameter) and operational parameters (i.e. oscillation frequency). The aim of this work was to develop and characterizes the novel OFR as a bioreactor. Upon completion of the OFR development, the reactor was subjected to a certain experiment for bioreactor characterization. The parameters studied were temperature profile, volumetric mass transfer coefficient (kLa), water loss due to evaporation and sterilization hold. The results showed the OFR was able to maintain the set temperature and its sterility throughout the experiment duration of 24 hours. The water loss due to evaporation inside the OFR was negligible as it was less than 4%. The highest kLa obtained was 33.6 h-1 at an oscillation frequency of 5 Hz. The OFR has shown its suitability as a bioreactor through various experiments conducted and will be tested for the fermentation of E. coli in the future. Malaysian Society of Applied Biology 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/21770/1/Characterisation%20of%20the%20Oscillatory%20Flow.pdf Norfaezahtul, Nor Azaini and N., Masngut (2018) Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli. Malaysian Applied Biology, 47 (2). pp. 119-124. ISSN 0126-8643 http://www.mabjournal.com/index.php?option=com_content&view=article&id=760&catid=59:current-view&Itemid=56
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Norfaezahtul, Nor Azaini N., Masngut Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli
description	Oscillatory Flow Reactor (OFR) is a novel type of tubular reactor consists of an equally spaced orifice baffles fitted inside the column of the reactor. The mixing in the OFR can be controlled by a combination of geometrical (i.e. baffles and orifice diameter) and operational parameters (i.e. oscillation frequency). The aim of this work was to develop and characterizes the novel OFR as a bioreactor. Upon completion of the OFR development, the reactor was subjected to a certain experiment for bioreactor characterization. The parameters studied were temperature profile, volumetric mass transfer coefficient (kLa), water loss due to evaporation and sterilization hold. The results showed the OFR was able to maintain the set temperature and its sterility throughout the experiment duration of 24 hours. The water loss due to evaporation inside the OFR was negligible as it was less than 4%. The highest kLa obtained was 33.6 h-1 at an oscillation frequency of 5 Hz. The OFR has shown its suitability as a bioreactor through various experiments conducted and will be tested for the fermentation of E. coli in the future.
format	Article
author	Norfaezahtul, Nor Azaini N., Masngut
author_facet	Norfaezahtul, Nor Azaini N., Masngut
author_sort	Norfaezahtul, Nor Azaini
title	Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli
title_short	Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli
title_full	Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli
title_fullStr	Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli
title_full_unstemmed	Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli
title_sort	characterisation of the oscillatory flow reactor for the fermentation of escherichia coli
publisher	Malaysian Society of Applied Biology
publishDate	2018
url	http://umpir.ump.edu.my/id/eprint/21770/ http://umpir.ump.edu.my/id/eprint/21770/ http://umpir.ump.edu.my/id/eprint/21770/1/Characterisation%20of%20the%20Oscillatory%20Flow.pdf
first_indexed	2023-09-18T22:32:05Z
last_indexed	2023-09-18T22:32:05Z
_version_	1777416353180811264

Characterisation of the Oscillatory Flow Reactor for the Fermentation of Escherichia coli

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