Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review

Thermoresponsive polymers have been attractively and scientifically significant in the recent years due to the utilization of various pharmaceutical and biomedical formulations. Poly(N-vinylcaprolactam) (PNVCL) is a temperature-responsive polymer, only second to poly(N-isopropylacrylamide) (PNIPAM),...

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Main Authors: Marwah Noori, Mohammed, Kamal, Yusoh, Jun Haslinda, Shariffuddin
Format: Article
Language:English
Published: American Scientific Publishers 2018
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/20658/
http://umpir.ump.edu.my/id/eprint/20658/
http://umpir.ump.edu.my/id/eprint/20658/
http://umpir.ump.edu.my/id/eprint/20658/1/Poly%28N-vinyl%20caprolactam%29%20thermoresponsive%20polymer%20in%20novel-fkksa-2018.pdf
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spelling ump-206582018-10-17T08:14:43Z http://umpir.ump.edu.my/id/eprint/20658/ Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review Marwah Noori, Mohammed Kamal, Yusoh Jun Haslinda, Shariffuddin TP Chemical technology Thermoresponsive polymers have been attractively and scientifically significant in the recent years due to the utilization of various pharmaceutical and biomedical formulations. Poly(N-vinylcaprolactam) (PNVCL) is a temperature-responsive polymer, only second to poly(N-isopropylacrylamide) (PNIPAM), the most popular temperature-responsive polymer. PNVCL should be considered an important focus due to the phase transition temperature of such polymer that is close to the physiological temperature. PNVCL is a polymer which offers unrivaled qualities for different potential medical device applications. Specifically, it offers one kind of thermoresponsive abilities, which satisfies the material innovation imperatives required in focused drug delivery applications. PNVCL and PNIPAM polymers are well-studied thermoresponsive abilities since its lower critical solution temperature (LCST) is near the physiological temperature and has mostly been used in biomedical applications. Therefore, it can be investigated as a potential candidate for pharmaceutical utilization. This review highlights a comparison of PNVCL with PNIPAM regarding comparable characteristics which also delve into selected examples and the most recent published of applications based on PNVCL with a specific focus on drug delivery system. The consequence exhibits that the PNVCL will play a pivotal role in nanotechnology and the environment. American Scientific Publishers 2018 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/20658/1/Poly%28N-vinyl%20caprolactam%29%20thermoresponsive%20polymer%20in%20novel-fkksa-2018.pdf Marwah Noori, Mohammed and Kamal, Yusoh and Jun Haslinda, Shariffuddin (2018) Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review. Materials Express, 8 (1). pp. 21-34. ISSN 2158-5849 https://doi.org/10.1166/mex.2018.1406 doi: 10.1166/mex.2018.1406
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Marwah Noori, Mohammed
Kamal, Yusoh
Jun Haslinda, Shariffuddin
Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review
description Thermoresponsive polymers have been attractively and scientifically significant in the recent years due to the utilization of various pharmaceutical and biomedical formulations. Poly(N-vinylcaprolactam) (PNVCL) is a temperature-responsive polymer, only second to poly(N-isopropylacrylamide) (PNIPAM), the most popular temperature-responsive polymer. PNVCL should be considered an important focus due to the phase transition temperature of such polymer that is close to the physiological temperature. PNVCL is a polymer which offers unrivaled qualities for different potential medical device applications. Specifically, it offers one kind of thermoresponsive abilities, which satisfies the material innovation imperatives required in focused drug delivery applications. PNVCL and PNIPAM polymers are well-studied thermoresponsive abilities since its lower critical solution temperature (LCST) is near the physiological temperature and has mostly been used in biomedical applications. Therefore, it can be investigated as a potential candidate for pharmaceutical utilization. This review highlights a comparison of PNVCL with PNIPAM regarding comparable characteristics which also delve into selected examples and the most recent published of applications based on PNVCL with a specific focus on drug delivery system. The consequence exhibits that the PNVCL will play a pivotal role in nanotechnology and the environment.
format Article
author Marwah Noori, Mohammed
Kamal, Yusoh
Jun Haslinda, Shariffuddin
author_facet Marwah Noori, Mohammed
Kamal, Yusoh
Jun Haslinda, Shariffuddin
author_sort Marwah Noori, Mohammed
title Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review
title_short Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review
title_full Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review
title_fullStr Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review
title_full_unstemmed Poly(N-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: A review
title_sort poly(n-vinyl caprolactam) thermoresponsive polymer in novel drug delivery systems: a review
publisher American Scientific Publishers
publishDate 2018
url http://umpir.ump.edu.my/id/eprint/20658/
http://umpir.ump.edu.my/id/eprint/20658/
http://umpir.ump.edu.my/id/eprint/20658/
http://umpir.ump.edu.my/id/eprint/20658/1/Poly%28N-vinyl%20caprolactam%29%20thermoresponsive%20polymer%20in%20novel-fkksa-2018.pdf
first_indexed 2023-09-18T22:29:55Z
last_indexed 2023-09-18T22:29:55Z
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