The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase

The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase

A liquid anionic-zwitterionic surfactant-based aqueous two-phase extraction was developed and applied for the extraction of erythromycin. Erythromycin solubilization from aqueous to reverse micelle phase was studied. Zwitterion SB3-18 surfactant was added to ionic solution of bis(2-ethylhexyl) sulfo...

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Main Authors: S. N., Mohamad Aziz, Mimi Sakinah, A. M.
Format: Article
Language:English
Published: Bangladesh University of Engineering and Technology 2017
Subjects:
T Technology (General)
Online Access:http://umpir.ump.edu.my/id/eprint/20605/
http://umpir.ump.edu.my/id/eprint/20605/
http://umpir.ump.edu.my/id/eprint/20605/
http://umpir.ump.edu.my/id/eprint/20605/1/The%20Solubilization%20and%20Extraction%20Parameters%20of%20Erythromycin%20from%20Aqueous%20Phase%20Into%20Mixed%20AOT-SB3-%2018%20Reverse%20Micelle%20Phase.pdf
id ump-20605
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spelling ump-206052018-02-23T02:58:47Z http://umpir.ump.edu.my/id/eprint/20605/ The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase S. N., Mohamad Aziz Mimi Sakinah, A. M. T Technology (General) A liquid anionic-zwitterionic surfactant-based aqueous two-phase extraction was developed and applied for the extraction of erythromycin. Erythromycin solubilization from aqueous to reverse micelle phase was studied. Zwitterion SB3-18 surfactant was added to ionic solution of bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) to form an organic mixed micellar phase. Erythromycin was then added to the mixtures and two clear phases were formed. The parameters affecting erythromycin solubilization including AOT concentration (20.0 ? 120.0 g/L), zwitterion concentration (6.0 ? 16.0 g/L), NaCl concentration (0.0 ? 25.0 g/L) and aqueous pH (6.0 ? 9.0) were investigated via statistical software. Solubilization of erythromycin into mixed reverse micelle could be easily evaluated by the measurement of erythromycin concentration in the organic phase. The results showed that AOT and zwitterion concentration governed the erythromycin solubilization by a factor of 4.562 based on the Pareto chart. Bangladesh University of Engineering and Technology 2017 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/20605/1/The%20Solubilization%20and%20Extraction%20Parameters%20of%20Erythromycin%20from%20Aqueous%20Phase%20Into%20Mixed%20AOT-SB3-%2018%20Reverse%20Micelle%20Phase.pdf S. N., Mohamad Aziz and Mimi Sakinah, A. M. (2017) The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase. Chemical Engineering Research Bulletin, 19 (Special). pp. 123-128. ISSN 0379-7678 (Print); 2072-9510 (Online) https://www.banglajol.info/index.php/CERB/article/view/33806 DOI: http://dx.doi.org/10.3329/cerb.v19i0.33806
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic T Technology (General)
spellingShingle T Technology (General)
S. N., Mohamad Aziz
Mimi Sakinah, A. M.
The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase
description A liquid anionic-zwitterionic surfactant-based aqueous two-phase extraction was developed and applied for the extraction of erythromycin. Erythromycin solubilization from aqueous to reverse micelle phase was studied. Zwitterion SB3-18 surfactant was added to ionic solution of bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) to form an organic mixed micellar phase. Erythromycin was then added to the mixtures and two clear phases were formed. The parameters affecting erythromycin solubilization including AOT concentration (20.0 ? 120.0 g/L), zwitterion concentration (6.0 ? 16.0 g/L), NaCl concentration (0.0 ? 25.0 g/L) and aqueous pH (6.0 ? 9.0) were investigated via statistical software. Solubilization of erythromycin into mixed reverse micelle could be easily evaluated by the measurement of erythromycin concentration in the organic phase. The results showed that AOT and zwitterion concentration governed the erythromycin solubilization by a factor of 4.562 based on the Pareto chart.
format Article
author S. N., Mohamad Aziz
Mimi Sakinah, A. M.
author_facet S. N., Mohamad Aziz
Mimi Sakinah, A. M.
author_sort S. N., Mohamad Aziz
title The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase
title_short The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase
title_full The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase
title_fullStr The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase
title_full_unstemmed The Solubilization and Extraction Parameters of Erythromycin from Aqueous Phase Into Mixed AOT/SB3-18 Reverse Micelle Phase
title_sort solubilization and extraction parameters of erythromycin from aqueous phase into mixed aot/sb3-18 reverse micelle phase
publisher Bangladesh University of Engineering and Technology
publishDate 2017
url http://umpir.ump.edu.my/id/eprint/20605/
http://umpir.ump.edu.my/id/eprint/20605/
http://umpir.ump.edu.my/id/eprint/20605/
http://umpir.ump.edu.my/id/eprint/20605/1/The%20Solubilization%20and%20Extraction%20Parameters%20of%20Erythromycin%20from%20Aqueous%20Phase%20Into%20Mixed%20AOT-SB3-%2018%20Reverse%20Micelle%20Phase.pdf
first_indexed 2023-09-18T22:29:49Z
last_indexed 2023-09-18T22:29:49Z
_version_ 1777416210224250880

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