Seaweed Bioactivity: Effects on glucose liberation

Hyperglycaemia (high blood sugar levels) is one of the risk factor of type 2 diabetes (T2D) when it is sustained over a longer period of time. Various factors that can lead to high blood glucose levels include glucose absorption by the small intestine and the production of glucose by liver cells. Ma...

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Main Author: Nazikussabah, Zaharudin
Other Authors: Dragsted, Lars
Format: Book
Language:English
Published: University of Copenhagen 2017
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/19763/
http://umpir.ump.edu.my/id/eprint/19763/1/NAZIKUSSABAH_VERSION%201%2028%20DEC%202017.pdf
id ump-19763
recordtype eprints
spelling ump-197632018-04-16T08:20:39Z http://umpir.ump.edu.my/id/eprint/19763/ Seaweed Bioactivity: Effects on glucose liberation Nazikussabah, Zaharudin Q Science (General) Hyperglycaemia (high blood sugar levels) is one of the risk factor of type 2 diabetes (T2D) when it is sustained over a longer period of time. Various factors that can lead to high blood glucose levels include glucose absorption by the small intestine and the production of glucose by liver cells. Maintenance of normal plasma glucose concentration is essential for the human health. Diet and exercise play important role to control blood sugar level. Limiting intake of high Glycaemic Index (GI) foods as part of a balanced diet is known to be important. In addition, having the right food intake such as functional foods that affect the blood sugar increase, e.g by containing inhibitors of α-amylase and/or α-glucosidase, may also help lowering the average blood sugar levels. Thus, such foods may in theory help to lower blood glucose postprandially and could potentially help delay the development of T2D in subjects with impaired glucose tolerance who regularly consumes starchy foods. The present study involved the investigation of crude extracts of dried edible seaweeds in inhibiting the carbohydrate digestive enzymes, α-amylase and α-glucosidase. Bioactive compounds from selected edible seaweeds that inhibit α-amylase and α-glucosidase were identified. The edible seaweeds that were showing high potential for inhibiting the enzymes were selected to investigate their effect on the postprandial blood glucose and insulin levels following a starch load in a human meal study. University of Copenhagen Dragsted, Lars 2017-11 Book PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/19763/1/NAZIKUSSABAH_VERSION%201%2028%20DEC%202017.pdf Nazikussabah, Zaharudin (2017) Seaweed Bioactivity: Effects on glucose liberation. University of Copenhagen, Frederiksnerg, Denmark. ISBN 978-87-7209-091-7
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
Nazikussabah, Zaharudin
Seaweed Bioactivity: Effects on glucose liberation
description Hyperglycaemia (high blood sugar levels) is one of the risk factor of type 2 diabetes (T2D) when it is sustained over a longer period of time. Various factors that can lead to high blood glucose levels include glucose absorption by the small intestine and the production of glucose by liver cells. Maintenance of normal plasma glucose concentration is essential for the human health. Diet and exercise play important role to control blood sugar level. Limiting intake of high Glycaemic Index (GI) foods as part of a balanced diet is known to be important. In addition, having the right food intake such as functional foods that affect the blood sugar increase, e.g by containing inhibitors of α-amylase and/or α-glucosidase, may also help lowering the average blood sugar levels. Thus, such foods may in theory help to lower blood glucose postprandially and could potentially help delay the development of T2D in subjects with impaired glucose tolerance who regularly consumes starchy foods. The present study involved the investigation of crude extracts of dried edible seaweeds in inhibiting the carbohydrate digestive enzymes, α-amylase and α-glucosidase. Bioactive compounds from selected edible seaweeds that inhibit α-amylase and α-glucosidase were identified. The edible seaweeds that were showing high potential for inhibiting the enzymes were selected to investigate their effect on the postprandial blood glucose and insulin levels following a starch load in a human meal study.
author2 Dragsted, Lars
author_facet Dragsted, Lars
Nazikussabah, Zaharudin
format Book
author Nazikussabah, Zaharudin
author_sort Nazikussabah, Zaharudin
title Seaweed Bioactivity: Effects on glucose liberation
title_short Seaweed Bioactivity: Effects on glucose liberation
title_full Seaweed Bioactivity: Effects on glucose liberation
title_fullStr Seaweed Bioactivity: Effects on glucose liberation
title_full_unstemmed Seaweed Bioactivity: Effects on glucose liberation
title_sort seaweed bioactivity: effects on glucose liberation
publisher University of Copenhagen
publishDate 2017
url http://umpir.ump.edu.my/id/eprint/19763/
http://umpir.ump.edu.my/id/eprint/19763/1/NAZIKUSSABAH_VERSION%201%2028%20DEC%202017.pdf
first_indexed 2023-09-18T22:28:20Z
last_indexed 2023-09-18T22:28:20Z
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