Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties

Objective: A novel cross-linked keratin hydrogel was prepared by integrating keratin from chicken feather into an aloe-vera, Chitosan and honey based dressing formulation separately. Methods: Keratin fibres extracted from chicken feathers are eco-friendly, non-abrasive, biodegradable, insoluble in...

Full description

Bibliographic Details
Main Authors: Priyaah, Kumaran, Gupta, Arun, Sharma, Swati
Format: Article
Language:English
Published: Innovare Academic Sciences 2017
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/19710/
http://umpir.ump.edu.my/id/eprint/19710/
http://umpir.ump.edu.my/id/eprint/19710/
http://umpir.ump.edu.my/id/eprint/19710/1/fkksa-2017-arun-Wound%20healing%20hydrogel%20Updated.pdf
id ump-19710
recordtype eprints
spelling ump-197102019-09-10T03:09:30Z http://umpir.ump.edu.my/id/eprint/19710/ Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties Priyaah, Kumaran Gupta, Arun Sharma, Swati TP Chemical technology Objective: A novel cross-linked keratin hydrogel was prepared by integrating keratin from chicken feather into an aloe-vera, Chitosan and honey based dressing formulation separately. Methods: Keratin fibres extracted from chicken feathers are eco-friendly, non-abrasive, biodegradable, insoluble in organic solvents and having good mechanical properties, hydrophobic behaviour, low density and finally cheap. Keratin based hydrogels were prepared with five types of ingredients and studied for their wound healing properties. The analysis of keratin-based hydrogel was done by Fourier Transform Infra-red Spectroscopy (FTIR) and X-ray diffraction (XRD) analysis. Results: Keratinocytes containing keratin travel from the wound border to initiate the process of healing. The characteristics of keratin-based hydrogel derived from chicken feather made it an effective wound care therapeutic product. X-ray diffraction (XRD) analysis showed the crystallinity index in between 30-50% of the hydrogen. Conclusion: The test for swelling and solubility were carried out on the hydrogen to determine the solid content and water absorbance capacity. Overall, this product is safe to use as an effective wound healing product with appropriate properties. Innovare Academic Sciences 2017 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/19710/1/fkksa-2017-arun-Wound%20healing%20hydrogel%20Updated.pdf Priyaah, Kumaran and Gupta, Arun and Sharma, Swati (2017) Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties. International Journal of Pharmacy and Pharmaceutical Sciences, 9 (2). pp. 171-178. ISSN 0975–1491 http://dx.doi.org/10.22159/ijpps.2017v9i2.15620 DOI: 10.22159/ijpps.2017v9i2.15620
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Priyaah, Kumaran
Gupta, Arun
Sharma, Swati
Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties
description Objective: A novel cross-linked keratin hydrogel was prepared by integrating keratin from chicken feather into an aloe-vera, Chitosan and honey based dressing formulation separately. Methods: Keratin fibres extracted from chicken feathers are eco-friendly, non-abrasive, biodegradable, insoluble in organic solvents and having good mechanical properties, hydrophobic behaviour, low density and finally cheap. Keratin based hydrogels were prepared with five types of ingredients and studied for their wound healing properties. The analysis of keratin-based hydrogel was done by Fourier Transform Infra-red Spectroscopy (FTIR) and X-ray diffraction (XRD) analysis. Results: Keratinocytes containing keratin travel from the wound border to initiate the process of healing. The characteristics of keratin-based hydrogel derived from chicken feather made it an effective wound care therapeutic product. X-ray diffraction (XRD) analysis showed the crystallinity index in between 30-50% of the hydrogen. Conclusion: The test for swelling and solubility were carried out on the hydrogen to determine the solid content and water absorbance capacity. Overall, this product is safe to use as an effective wound healing product with appropriate properties.
format Article
author Priyaah, Kumaran
Gupta, Arun
Sharma, Swati
author_facet Priyaah, Kumaran
Gupta, Arun
Sharma, Swati
author_sort Priyaah, Kumaran
title Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties
title_short Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties
title_full Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties
title_fullStr Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties
title_full_unstemmed Synthesis of Wound-Healing Keratin Hydrogels Using Chicken Feathers Proteins and Its Properties
title_sort synthesis of wound-healing keratin hydrogels using chicken feathers proteins and its properties
publisher Innovare Academic Sciences
publishDate 2017
url http://umpir.ump.edu.my/id/eprint/19710/
http://umpir.ump.edu.my/id/eprint/19710/
http://umpir.ump.edu.my/id/eprint/19710/
http://umpir.ump.edu.my/id/eprint/19710/1/fkksa-2017-arun-Wound%20healing%20hydrogel%20Updated.pdf
first_indexed 2023-09-18T22:28:14Z
last_indexed 2023-09-18T22:28:14Z
_version_ 1777416110959755264