Performance of Glycemic Control Protocol and Virtual Trial

Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must...

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Main Authors:	Fatanah, M. Suhaimi, Ummu Kulthum, Jamaludin, Normy Norfiza, A. Razak, Azrina, Md Ralib, Mohd Basri, Mat Nor
Format:	Article
Language:	English
Published:	Publishing Technology 2017
Subjects:	Q Science (General) QA Mathematics R Medicine (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/1/fkm-2017-ummu-performance%20of%20glycemic.pdf

id	ump-19703
recordtype	eprints
spelling	ump-197032018-11-30T01:56:38Z http://umpir.ump.edu.my/id/eprint/19703/ Performance of Glycemic Control Protocol and Virtual Trial Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor Q Science (General) QA Mathematics R Medicine (General) Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort. Publishing Technology 2017-06-01 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/19703/1/fkm-2017-ummu-performance%20of%20glycemic.pdf Fatanah, M. Suhaimi and Ummu Kulthum, Jamaludin and Normy Norfiza, A. Razak and Azrina, Md Ralib and Mohd Basri, Mat Nor (2017) Performance of Glycemic Control Protocol and Virtual Trial. Advanced Science Letters, 23 (6). pp. 5415-5418. ISSN 1936-6612 https://doi.org/10.1166/asl.2017.7389 doi: 10.1166/asl.2017.7389
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	Q Science (General) QA Mathematics R Medicine (General)
spellingShingle	Q Science (General) QA Mathematics R Medicine (General) Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor Performance of Glycemic Control Protocol and Virtual Trial
description	Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort.
format	Article
author	Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor
author_facet	Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor
author_sort	Fatanah, M. Suhaimi
title	Performance of Glycemic Control Protocol and Virtual Trial
title_short	Performance of Glycemic Control Protocol and Virtual Trial
title_full	Performance of Glycemic Control Protocol and Virtual Trial
title_fullStr	Performance of Glycemic Control Protocol and Virtual Trial
title_full_unstemmed	Performance of Glycemic Control Protocol and Virtual Trial
title_sort	performance of glycemic control protocol and virtual trial
publisher	Publishing Technology
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/1/fkm-2017-ummu-performance%20of%20glycemic.pdf
first_indexed	2023-09-18T22:28:13Z
last_indexed	2023-09-18T22:28:13Z
_version_	1777416109951025152

Performance of Glycemic Control Protocol and Virtual Trial

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