Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance

Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance

The aim of this study is the ion channel model with noise variance as approximations to the HodgkinHuxley model proposed, due to the Hodgkin-Huxley model affected when inserting some colored noise terms inside the conductances, where those effects captured by colored noise because of the gate multip...

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Main Authors: Khudhur, Ahmed M., Hashim, Yasir, Abdalla, Ahmed N.
Format: Article
Language:English
Published: Maxwell Scientific Publication Corp. 2017
Subjects:
TK Electrical engineering. Electronics Nuclear engineering
Online Access:http://umpir.ump.edu.my/id/eprint/19251/
http://umpir.ump.edu.my/id/eprint/19251/
http://umpir.ump.edu.my/id/eprint/19251/
http://umpir.ump.edu.my/id/eprint/19251/1/msproof.php_doi%3Drjaset.14.4789
id ump-19251
recordtype eprints
spelling ump-192512018-10-03T07:27:25Z http://umpir.ump.edu.my/id/eprint/19251/ Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance Khudhur, Ahmed M. Hashim, Yasir Abdalla, Ahmed N. TK Electrical engineering. Electronics Nuclear engineering The aim of this study is the ion channel model with noise variance as approximations to the HodgkinHuxley model proposed, due to the Hodgkin-Huxley model affected when inserting some colored noise terms inside the conductances, where those effects captured by colored noise because of the gate multiplicity. Firstly, it introduces the comparison of ion channel based on Fox, Lu and Linaro models. Additionally, in order to overcome the limitations of other parameter estimation methods, the proposed method fully constrains their models and obtains all model's capabilities of reproducing the data. Finally, the relationship between the sequence of colored noise and the spike frequency are simulated efficiently each gate compared with microscopic simulations of the stochastic Markov process method. In simulation results, the spiking rate generated from the proposed model very close to microscopic simulations and doesn’t effect by the membrane size. Maxwell Scientific Publication Corp. 2017-07-15 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/19251/1/msproof.php_doi%3Drjaset.14.4789 Khudhur, Ahmed M. and Hashim, Yasir and Abdalla, Ahmed N. (2017) Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance. Research Journal of Applied Sciences, Engineering and Technology, 14 (7). pp. 262-270. ISSN 2040-7459 http://www.maxwellsci.com/msproof.php?doi=rjaset.14.4789 doi: 10.19026/rjaset.14.4789
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Khudhur, Ahmed M.
Hashim, Yasir
Abdalla, Ahmed N.
Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance
description The aim of this study is the ion channel model with noise variance as approximations to the HodgkinHuxley model proposed, due to the Hodgkin-Huxley model affected when inserting some colored noise terms inside the conductances, where those effects captured by colored noise because of the gate multiplicity. Firstly, it introduces the comparison of ion channel based on Fox, Lu and Linaro models. Additionally, in order to overcome the limitations of other parameter estimation methods, the proposed method fully constrains their models and obtains all model's capabilities of reproducing the data. Finally, the relationship between the sequence of colored noise and the spike frequency are simulated efficiently each gate compared with microscopic simulations of the stochastic Markov process method. In simulation results, the spiking rate generated from the proposed model very close to microscopic simulations and doesn’t effect by the membrane size.
format Article
author Khudhur, Ahmed M.
Hashim, Yasir
Abdalla, Ahmed N.
author_facet Khudhur, Ahmed M.
Hashim, Yasir
Abdalla, Ahmed N.
author_sort Khudhur, Ahmed M.
title Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance
title_short Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance
title_full Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance
title_fullStr Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance
title_full_unstemmed Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance
title_sort development of neuron ion channel model using colored noise terms in the conductance
publisher Maxwell Scientific Publication Corp.
publishDate 2017
url http://umpir.ump.edu.my/id/eprint/19251/
http://umpir.ump.edu.my/id/eprint/19251/
http://umpir.ump.edu.my/id/eprint/19251/
http://umpir.ump.edu.my/id/eprint/19251/1/msproof.php_doi%3Drjaset.14.4789
first_indexed 2023-09-18T22:27:36Z
last_indexed 2023-09-18T22:27:36Z
_version_ 1777416070752108544

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