Performance of blood glucose management protocols in HTAA intensive care unit
Insulin Infusion Therapy (IIT) has been implemented in Malaysia Intensive Care Unit (ICU) for decades to control blood glucose level (BGL) among critically ill patients. In this study, clinical data of 210 patients treated with IIT-HTAA protocol and the minimum length of stay of 1 day were analysed....
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2017
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ump-182512018-11-30T01:57:19Z http://umpir.ump.edu.my/id/eprint/18251/ Performance of blood glucose management protocols in HTAA intensive care unit H. M., Luqman W. Zuhriraihan, W. M. Zulkifly C. Zafirah, Rosly Khalijah, Khalid Ummu Kulthum, Jamaludin Azrina, Md. Ralib Mohd Basri, Mat Nor TJ Mechanical engineering and machinery Insulin Infusion Therapy (IIT) has been implemented in Malaysia Intensive Care Unit (ICU) for decades to control blood glucose level (BGL) among critically ill patients. In this study, clinical data of 210 patients treated with IIT-HTAA protocol and the minimum length of stay of 1 day were analysed. BGL, insulin and nutrition inputs were fitted using Intensive Control Insulin Nutrition Glucose (ICING) model to generate the insulin sensitivity numerically by iterative-integral method. The 95% of confidence interval and Kolmogorov-Smirnov test (p<;0.05) were used to evaluate the performance of protocol between the Stochastic TARgeted (STAR) and HTAA protocols per cohorts and per patients. Results indicates BG median [with IQR] recorded in STAR protocol for the whole cohort statistics is lower than HTAA Protocol where 7.4 mmol/L [5.7-9.4] and 8.6 mmol/L [6.8-10.9] respectively. STAR is successful in lowering the BGL which can be seen from the % BG > 10.0 mmol/L is 19.7% while 32.8% for HTAA Protocol. The drawback from this positive result is the increment of hypoglycaemic patients (HTAA Protocol: 9; STAR: 36). Thus, STAR is the best solution in controlling the patients' BG level especially in Malaysian cohort but the enhancement of STAR have to be done to prevent the risk of hypoglycaemia by introducing patient-specific nutrition controller that can be combined with insulin infusion. IEEE 2017-03 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/18251/1/Performance%20of%20Blood%20Glucose%20Management%20Protocols%20in%20HTAA%20Intensive%20Care%20Unit.pdf pdf en http://umpir.ump.edu.my/id/eprint/18251/2/Performance%20of%20Blood%20Glucose%20Management%20Protocols%20in%20HTAA%20Intensive%20Care%20Unit%201.pdf H. M., Luqman and W. Zuhriraihan, W. M. Zulkifly and C. Zafirah, Rosly and Khalijah, Khalid and Ummu Kulthum, Jamaludin and Azrina, Md. Ralib and Mohd Basri, Mat Nor (2017) Performance of blood glucose management protocols in HTAA intensive care unit. In: IEEE International Conference on Automatic Control and Intelligent Systems (I2CACIS 2016), 22 October 2016 , UniversIti Teknologi Mara Shah Alam, Malaysia. pp. 156-161.. ISBN 978-1-5090-4186-2 https://ieeexplore.ieee.org/document/7885307/ |
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TJ Mechanical engineering and machinery |
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TJ Mechanical engineering and machinery H. M., Luqman W. Zuhriraihan, W. M. Zulkifly C. Zafirah, Rosly Khalijah, Khalid Ummu Kulthum, Jamaludin Azrina, Md. Ralib Mohd Basri, Mat Nor Performance of blood glucose management protocols in HTAA intensive care unit |
description |
Insulin Infusion Therapy (IIT) has been implemented in Malaysia Intensive Care Unit (ICU) for decades to control blood glucose level (BGL) among critically ill patients. In this study, clinical data of 210 patients treated with IIT-HTAA protocol and the minimum length of stay of 1 day were analysed. BGL, insulin and nutrition inputs were fitted using Intensive Control Insulin Nutrition Glucose (ICING) model to generate the insulin sensitivity numerically by iterative-integral method. The 95% of confidence interval and Kolmogorov-Smirnov test (p<;0.05) were used to evaluate the performance of protocol between the Stochastic TARgeted (STAR) and HTAA protocols per cohorts and per patients. Results indicates BG median [with IQR] recorded in STAR protocol for the whole cohort statistics is lower than HTAA Protocol where 7.4 mmol/L [5.7-9.4] and 8.6 mmol/L [6.8-10.9] respectively. STAR is successful in lowering the BGL which can be seen from the % BG > 10.0 mmol/L is 19.7% while 32.8% for HTAA Protocol. The drawback from this positive result is the increment of hypoglycaemic patients (HTAA Protocol: 9; STAR: 36). Thus, STAR is the best solution in controlling the patients' BG level especially in Malaysian cohort but the enhancement of STAR have to be done to prevent the risk of hypoglycaemia by introducing patient-specific nutrition controller that can be combined with insulin infusion. |
format |
Conference or Workshop Item |
author |
H. M., Luqman W. Zuhriraihan, W. M. Zulkifly C. Zafirah, Rosly Khalijah, Khalid Ummu Kulthum, Jamaludin Azrina, Md. Ralib Mohd Basri, Mat Nor |
author_facet |
H. M., Luqman W. Zuhriraihan, W. M. Zulkifly C. Zafirah, Rosly Khalijah, Khalid Ummu Kulthum, Jamaludin Azrina, Md. Ralib Mohd Basri, Mat Nor |
author_sort |
H. M., Luqman |
title |
Performance of blood glucose management protocols in HTAA intensive care unit |
title_short |
Performance of blood glucose management protocols in HTAA intensive care unit |
title_full |
Performance of blood glucose management protocols in HTAA intensive care unit |
title_fullStr |
Performance of blood glucose management protocols in HTAA intensive care unit |
title_full_unstemmed |
Performance of blood glucose management protocols in HTAA intensive care unit |
title_sort |
performance of blood glucose management protocols in htaa intensive care unit |
publisher |
IEEE |
publishDate |
2017 |
url |
http://umpir.ump.edu.my/id/eprint/18251/ http://umpir.ump.edu.my/id/eprint/18251/ http://umpir.ump.edu.my/id/eprint/18251/1/Performance%20of%20Blood%20Glucose%20Management%20Protocols%20in%20HTAA%20Intensive%20Care%20Unit.pdf http://umpir.ump.edu.my/id/eprint/18251/2/Performance%20of%20Blood%20Glucose%20Management%20Protocols%20in%20HTAA%20Intensive%20Care%20Unit%201.pdf |
first_indexed |
2023-09-18T22:25:45Z |
last_indexed |
2023-09-18T22:25:45Z |
_version_ |
1777415954257412096 |