Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells

Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is requ...

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Main Authors:	Siti Nursyahirah, Ahmad Latfi, Fahmi, Samsuri
Format:	Conference or Workshop Item
Language:	English English
Published:	IEEE 2017
Subjects:	TK Electrical engineering. Electronics Nuclear engineering
Online Access:	http://umpir.ump.edu.my/id/eprint/18226/ http://umpir.ump.edu.my/id/eprint/18226/ http://umpir.ump.edu.my/id/eprint/18226/1/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells.pdf http://umpir.ump.edu.my/id/eprint/18226/5/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells%201.pdf

id	ump-18226
recordtype	eprints
spelling	ump-182262018-07-18T06:52:54Z http://umpir.ump.edu.my/id/eprint/18226/ Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri TK Electrical engineering. Electronics Nuclear engineering Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is required for dielectrophoresis force (DEP) to implement manipulation technique, where the non-uniform AC is generated by microelectrodes designed. The current design has a limitation in term of electric field distribution pattern generated. Thus, ring microarray microelectrode pattern was designed and simulated using COMSOL Multiphysics 4.4 software for implementing one of the main objectives of this study, which is to investigate the electric field distribution resulting from the microelectrodes designed. To optimize the generated DEP force for manipulating biological cells, electric field simulation is very important. The electric field simulation performed by altering some microelectrode geometric design parameters such as the microelectrodes length and the distance between the microelectrodes and the microcavity. The simulation has been shown in this paper. This is intended to simulate the effect of an electric field that results when there are any changes to the geometric design of microelectrodes. Based on the simulation that has been done, the results show the distance between the microelectrodes and microcavity provide more impact in electric field distribution strength compared to the change of the microelectrodes size. IEEE 2017-04 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/18226/1/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells.pdf pdf en http://umpir.ump.edu.my/id/eprint/18226/5/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells%201.pdf Siti Nursyahirah, Ahmad Latfi and Fahmi, Samsuri (2017) Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells. In: 6th IEEE International Conference on Control System, Computing and Engineering (ICCSCE 2016), 25-27 November 2016 , PARK ROYAL Penang Resort, Penang; Malaysia. pp. 79-84.. ISBN 978-150901178-0 https://ieeexplore.ieee.org/document/7893549/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English
topic	TK Electrical engineering. Electronics Nuclear engineering
spellingShingle	TK Electrical engineering. Electronics Nuclear engineering Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
description	Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is required for dielectrophoresis force (DEP) to implement manipulation technique, where the non-uniform AC is generated by microelectrodes designed. The current design has a limitation in term of electric field distribution pattern generated. Thus, ring microarray microelectrode pattern was designed and simulated using COMSOL Multiphysics 4.4 software for implementing one of the main objectives of this study, which is to investigate the electric field distribution resulting from the microelectrodes designed. To optimize the generated DEP force for manipulating biological cells, electric field simulation is very important. The electric field simulation performed by altering some microelectrode geometric design parameters such as the microelectrodes length and the distance between the microelectrodes and the microcavity. The simulation has been shown in this paper. This is intended to simulate the effect of an electric field that results when there are any changes to the geometric design of microelectrodes. Based on the simulation that has been done, the results show the distance between the microelectrodes and microcavity provide more impact in electric field distribution strength compared to the change of the microelectrodes size.
format	Conference or Workshop Item
author	Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri
author_facet	Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri
author_sort	Siti Nursyahirah, Ahmad Latfi
title	Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
title_short	Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
title_full	Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
title_fullStr	Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
title_full_unstemmed	Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
title_sort	simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
publisher	IEEE
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/18226/ http://umpir.ump.edu.my/id/eprint/18226/ http://umpir.ump.edu.my/id/eprint/18226/1/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells.pdf http://umpir.ump.edu.my/id/eprint/18226/5/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells%201.pdf
first_indexed	2023-09-18T22:25:42Z
last_indexed	2023-09-18T22:25:42Z
_version_	1777415951624437760

Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells

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