Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield

Mahkota Dewa (Phaleria macrocarpa) is a popular herbal plant that is indigenous to Indonesia and Malaysia. The bioactive ingredients in the plant contain antihistamine, antioxidant, and anti-cancer compound. In this work, experimental study was performed using subcritical water extraction (SWE) meth...

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Main Authors:	Nurmaryam Aini, Hashim, Ummi Najihah, Md. Hashim, Siti Kholijah, Abdul Mudalip, Noorlisa, Harun, Fatmawati, Adam, Rohaida, Che Man, Siti Zubaidah, Sulaiman, Zatul Iffah, Mohd Arshad, Shalyda, Md Shaarani
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2017
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/18007/ http://umpir.ump.edu.my/id/eprint/18007/ http://umpir.ump.edu.my/id/eprint/18007/ http://umpir.ump.edu.my/id/eprint/18007/1/Nurmaryam_21_3_22.pdf

id	ump-18007
recordtype	eprints
spelling	ump-180072017-12-15T03:25:07Z http://umpir.ump.edu.my/id/eprint/18007/ Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield Nurmaryam Aini, Hashim Ummi Najihah, Md. Hashim Siti Kholijah, Abdul Mudalip Noorlisa, Harun Fatmawati, Adam Rohaida, Che Man Siti Zubaidah, Sulaiman Zatul Iffah, Mohd Arshad Shalyda, Md Shaarani TP Chemical technology Mahkota Dewa (Phaleria macrocarpa) is a popular herbal plant that is indigenous to Indonesia and Malaysia. The bioactive ingredients in the plant contain antihistamine, antioxidant, and anti-cancer compound. In this work, experimental study was performed using subcritical water extraction (SWE) method to extract bioactive compound namely mangiferin from Mahkota Dewa fruits. A sequential screening strategy using one-factor-at-a-time (OFAT) was carried out at different solid to solvent ratios (30 – 70 g/L), temperatures (50 – 150 °C) and extraction times (3 – 7 hours). The yield of mangiferin extracted was measured using high performance liquid chromatography (HPLC). The results show that the solid to solvent ratio, extraction temperature and time cause significant effect on the mangiferin yield. The best operating conditions for extracting Mahkota Dewa fruit with subcritical method is 60 g/L solid to solvent ratio and 100°C extraction temperature for 5 hours with mangiferin yield of 3.202% w/w. Universiti Kebangsaan Malaysia 2017-06 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/18007/1/Nurmaryam_21_3_22.pdf Nurmaryam Aini, Hashim and Ummi Najihah, Md. Hashim and Siti Kholijah, Abdul Mudalip and Noorlisa, Harun and Fatmawati, Adam and Rohaida, Che Man and Siti Zubaidah, Sulaiman and Zatul Iffah, Mohd Arshad and Shalyda, Md Shaarani (2017) Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield. Malaysian Journal of Analytical Sciences, 21 (3). pp. 726-734. ISSN 1394-2506 http://www.ukm.my/mjas/mjas2017/ doi: 10.17576/mjas-2017-2103-22
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Nurmaryam Aini, Hashim Ummi Najihah, Md. Hashim Siti Kholijah, Abdul Mudalip Noorlisa, Harun Fatmawati, Adam Rohaida, Che Man Siti Zubaidah, Sulaiman Zatul Iffah, Mohd Arshad Shalyda, Md Shaarani Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield
description	Mahkota Dewa (Phaleria macrocarpa) is a popular herbal plant that is indigenous to Indonesia and Malaysia. The bioactive ingredients in the plant contain antihistamine, antioxidant, and anti-cancer compound. In this work, experimental study was performed using subcritical water extraction (SWE) method to extract bioactive compound namely mangiferin from Mahkota Dewa fruits. A sequential screening strategy using one-factor-at-a-time (OFAT) was carried out at different solid to solvent ratios (30 – 70 g/L), temperatures (50 – 150 °C) and extraction times (3 – 7 hours). The yield of mangiferin extracted was measured using high performance liquid chromatography (HPLC). The results show that the solid to solvent ratio, extraction temperature and time cause significant effect on the mangiferin yield. The best operating conditions for extracting Mahkota Dewa fruit with subcritical method is 60 g/L solid to solvent ratio and 100°C extraction temperature for 5 hours with mangiferin yield of 3.202% w/w.
format	Article
author	Nurmaryam Aini, Hashim Ummi Najihah, Md. Hashim Siti Kholijah, Abdul Mudalip Noorlisa, Harun Fatmawati, Adam Rohaida, Che Man Siti Zubaidah, Sulaiman Zatul Iffah, Mohd Arshad Shalyda, Md Shaarani
author_facet	Nurmaryam Aini, Hashim Ummi Najihah, Md. Hashim Siti Kholijah, Abdul Mudalip Noorlisa, Harun Fatmawati, Adam Rohaida, Che Man Siti Zubaidah, Sulaiman Zatul Iffah, Mohd Arshad Shalyda, Md Shaarani
author_sort	Nurmaryam Aini, Hashim
title	Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield
title_short	Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield
title_full	Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield
title_fullStr	Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield
title_full_unstemmed	Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield
title_sort	extraction of bioactive compounds (mangiferin) from mahkota dewa (phaleria macrocarpa) fruits using subcritical water: effect of process parameters on extraction yield
publisher	Universiti Kebangsaan Malaysia
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/18007/ http://umpir.ump.edu.my/id/eprint/18007/ http://umpir.ump.edu.my/id/eprint/18007/ http://umpir.ump.edu.my/id/eprint/18007/1/Nurmaryam_21_3_22.pdf
first_indexed	2023-09-18T22:25:13Z
last_indexed	2023-09-18T22:25:13Z
_version_	1777415921552326656

Extraction of Bioactive Compounds (Mangiferin) from Mahkota Dewa (Phaleria macrocarpa) Fruits Using Subcritical Water: Effect of Process Parameters on Extraction Yield

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