Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement

Diabetes is a disease that causes the blood glucose level to rise and if left untreated, could yield in many complications such as amputations of body parts, muscle disorders and fatigue. The alarming increase in the number of patients suffering from diabetes requests for more studies to be conducte...

Full description

Bibliographic Details
Main Authors:	Munem, Osama A., Kasturi, Mahendran, Makky, Essam A., Normaiza, Z., Thanoon, Raid D., M. M., Yusoff
Format:	Conference or Workshop Item
Language:	English
Published:	Universiti Malaysia Pahang 2017
Subjects:	TD Environmental technology. Sanitary engineering
Online Access:	http://umpir.ump.edu.my/id/eprint/17623/ http://umpir.ump.edu.my/id/eprint/17623/1/20.%20Hypoglycemic%20effect%20of%20some%20ethnomedicinal%20plants%20and%20its%20applications%20on%20pancreas%20improvement.pdf

id	ump-17623
recordtype	eprints
spelling	ump-176232018-07-27T03:13:19Z http://umpir.ump.edu.my/id/eprint/17623/ Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement Munem, Osama A. Kasturi, Mahendran Makky, Essam A. Normaiza, Z. Thanoon, Raid D. M. M., Yusoff TD Environmental technology. Sanitary engineering Diabetes is a disease that causes the blood glucose level to rise and if left untreated, could yield in many complications such as amputations of body parts, muscle disorders and fatigue. The alarming increase in the number of patients suffering from diabetes requests for more studies to be conducted to find alternatives in producing a cure to this disease. Many chemical methods are adapted towards the treatment of diabetes, so it is crucial that studies on medicinal plants are carried out to produce a solution that does not rely on chemicals alone, and can inhibit the diabetic activity as much as the existing medications. This study was conducted to collect and extract ethnomedicinal plants from Malaysia using different solvents, to select the most potent ethnomedicinal plant extract using anti-diabetic screening assays and to screen for combination effects of the plant extracts on anti-diabetic activity. The plant extracts are then subjected to α- amylase and assays whereby detection of potent plants that result in more than 50% inhibition is selected. Selected plants are combined to one another in dual, triple and quadruple plant extract combinations and anti-diabetic assays are performed once again to find the most effective combination that gives the highest inhibition value. Once the combined inhibition values are obtained, these values determined and classified into synergistic and antagonistic groups depending on its relationship with one another, whether it enhances inhibition value or not. For alpha-amylase inhibition, the chloroform extract of E. longifolia gave the highest inhibition of α-amylase enzyme at 82.42%. Universiti Malaysia Pahang 2017 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/17623/1/20.%20Hypoglycemic%20effect%20of%20some%20ethnomedicinal%20plants%20and%20its%20applications%20on%20pancreas%20improvement.pdf Munem, Osama A. and Kasturi, Mahendran and Makky, Essam A. and Normaiza, Z. and Thanoon, Raid D. and M. M., Yusoff (2017) Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement. In: Proceedings of the FGIC 1st Conference on Governance & Integrity, 3-4 April 2017 , Yayasan Pahang, Kuantan, Malaysia. pp. 370-377.. ISBN 978-967-2054-37-5
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TD Environmental technology. Sanitary engineering
spellingShingle	TD Environmental technology. Sanitary engineering Munem, Osama A. Kasturi, Mahendran Makky, Essam A. Normaiza, Z. Thanoon, Raid D. M. M., Yusoff Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement
description	Diabetes is a disease that causes the blood glucose level to rise and if left untreated, could yield in many complications such as amputations of body parts, muscle disorders and fatigue. The alarming increase in the number of patients suffering from diabetes requests for more studies to be conducted to find alternatives in producing a cure to this disease. Many chemical methods are adapted towards the treatment of diabetes, so it is crucial that studies on medicinal plants are carried out to produce a solution that does not rely on chemicals alone, and can inhibit the diabetic activity as much as the existing medications. This study was conducted to collect and extract ethnomedicinal plants from Malaysia using different solvents, to select the most potent ethnomedicinal plant extract using anti-diabetic screening assays and to screen for combination effects of the plant extracts on anti-diabetic activity. The plant extracts are then subjected to α- amylase and assays whereby detection of potent plants that result in more than 50% inhibition is selected. Selected plants are combined to one another in dual, triple and quadruple plant extract combinations and anti-diabetic assays are performed once again to find the most effective combination that gives the highest inhibition value. Once the combined inhibition values are obtained, these values determined and classified into synergistic and antagonistic groups depending on its relationship with one another, whether it enhances inhibition value or not. For alpha-amylase inhibition, the chloroform extract of E. longifolia gave the highest inhibition of α-amylase enzyme at 82.42%.
format	Conference or Workshop Item
author	Munem, Osama A. Kasturi, Mahendran Makky, Essam A. Normaiza, Z. Thanoon, Raid D. M. M., Yusoff
author_facet	Munem, Osama A. Kasturi, Mahendran Makky, Essam A. Normaiza, Z. Thanoon, Raid D. M. M., Yusoff
author_sort	Munem, Osama A.
title	Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement
title_short	Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement
title_full	Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement
title_fullStr	Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement
title_full_unstemmed	Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement
title_sort	hypoglycemic effect of some ethnomedicinal plants and its applications on pancreas improvement
publisher	Universiti Malaysia Pahang
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/17623/ http://umpir.ump.edu.my/id/eprint/17623/1/20.%20Hypoglycemic%20effect%20of%20some%20ethnomedicinal%20plants%20and%20its%20applications%20on%20pancreas%20improvement.pdf
first_indexed	2023-09-18T22:24:27Z
last_indexed	2023-09-18T22:24:27Z
_version_	1777415872996966400

Hypoglycemic Effect of Some Ethnomedicinal Plants and Its Applications on Pancreas Improvement

Similar Items