Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal

Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal

Co-crystal is believed can improved physicochemical properties of an Active Pharmaceutical Ingredients (APis). Understanding in co-crystallization process is needed in order to have desirable crystal habits for materials. One of the studies that are important in designing co-crystallization process...

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Main Authors: E. N., Engku Mat Nasir, Fatinah, Ab Rahman, S., Abd Rahim, Raihana Z., Edros, N., Anuar
Format: Conference or Workshop Item
Language:English
Published: 2016
Subjects:
T Technology (General)
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/17064/
http://umpir.ump.edu.my/id/eprint/17064/1/Effect%20on%20Operating%20Parameters%20towards%20Metastable%20Zone%20Width%20of.pdf
id ump-17064
recordtype eprints
spelling ump-170642019-10-30T07:39:29Z http://umpir.ump.edu.my/id/eprint/17064/ Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal E. N., Engku Mat Nasir Fatinah, Ab Rahman S., Abd Rahim Raihana Z., Edros N., Anuar T Technology (General) TP Chemical technology Co-crystal is believed can improved physicochemical properties of an Active Pharmaceutical Ingredients (APis). Understanding in co-crystallization process is needed in order to have desirable crystal habits for materials. One of the studies that are important in designing co-crystallization process is kinetics study. In this research, carbamazepine (CBZ) and co-former saccharin (SAC) has been used to study the metastable zone width (MSZW) of the CBZ-SAC co-crystal in ethanol solution. The MSZW is studied by varying concentration of CBZ, mo) ratio values of SAC to CBZ and cooling rates used by polythermal method. Crystallization temperature and dissolution temperature is used to determine the maximum temperature difference ~Tmax using N)'vlt's equation. 2016 Conference or Workshop Item NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/17064/1/Effect%20on%20Operating%20Parameters%20towards%20Metastable%20Zone%20Width%20of.pdf E. N., Engku Mat Nasir and Fatinah, Ab Rahman and S., Abd Rahim and Raihana Z., Edros and N., Anuar (2016) Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal. In: The 18th International Conference on Crystal Growth and Epitaxy, 07-12 August 2016 , Nagoya, Japan. . (Unpublished)
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic T Technology (General)
TP Chemical technology
spellingShingle T Technology (General)
TP Chemical technology
E. N., Engku Mat Nasir
Fatinah, Ab Rahman
S., Abd Rahim
Raihana Z., Edros
N., Anuar
Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
description Co-crystal is believed can improved physicochemical properties of an Active Pharmaceutical Ingredients (APis). Understanding in co-crystallization process is needed in order to have desirable crystal habits for materials. One of the studies that are important in designing co-crystallization process is kinetics study. In this research, carbamazepine (CBZ) and co-former saccharin (SAC) has been used to study the metastable zone width (MSZW) of the CBZ-SAC co-crystal in ethanol solution. The MSZW is studied by varying concentration of CBZ, mo) ratio values of SAC to CBZ and cooling rates used by polythermal method. Crystallization temperature and dissolution temperature is used to determine the maximum temperature difference ~Tmax using N)'vlt's equation.
format Conference or Workshop Item
author E. N., Engku Mat Nasir
Fatinah, Ab Rahman
S., Abd Rahim
Raihana Z., Edros
N., Anuar
author_facet E. N., Engku Mat Nasir
Fatinah, Ab Rahman
S., Abd Rahim
Raihana Z., Edros
N., Anuar
author_sort E. N., Engku Mat Nasir
title Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
title_short Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
title_full Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
title_fullStr Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
title_full_unstemmed Effect on Operating Parameters Towards Metastable Zone Width of Carbamazepine-Saccharin Co-Crystal
title_sort effect on operating parameters towards metastable zone width of carbamazepine-saccharin co-crystal
publishDate 2016
url http://umpir.ump.edu.my/id/eprint/17064/
http://umpir.ump.edu.my/id/eprint/17064/1/Effect%20on%20Operating%20Parameters%20towards%20Metastable%20Zone%20Width%20of.pdf
first_indexed 2023-09-18T22:23:17Z
last_indexed 2023-09-18T22:23:17Z
_version_ 1777415799609229312

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