Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
Background The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be found in the roots of the kava-kava plant. In this study, the operational mec...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BioMed Central Ltd.
2016
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/1/fist-2016-nadeem-Flavokawain%20B%20induced1.pdf |
| Summary: | Background
The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be found in the roots of the kava-kava plant. In this study, the operational mechanism of the anti-cancer activity of a synthetic Flavokawain B (FKB) on two breast cancer cell lines, MCF-7 and MDA-MB231 was investigated. |
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