Bromelain: from Production to Commercialisation

Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants. It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and peel. High demand for bromelain has resulted in gradual increases in bromelain production. These increases have led...

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Main Authors:	Aizi Nor Mazila, Ramli, Tuan Norsyalieza, Tuan Aznan, Rosli, Md. Illias
Format:	Article
Language:	English
Published:	Wiley 2016
Subjects:	S Agriculture (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/16737/ http://umpir.ump.edu.my/id/eprint/16737/ http://umpir.ump.edu.my/id/eprint/16737/ http://umpir.ump.edu.my/id/eprint/16737/2/JSFA8122%20%281%29.pdf

id	ump-16737
recordtype	eprints
spelling	ump-167372018-07-26T01:55:20Z http://umpir.ump.edu.my/id/eprint/16737/ Bromelain: from Production to Commercialisation Aizi Nor Mazila, Ramli Tuan Norsyalieza, Tuan Aznan Rosli, Md. Illias S Agriculture (General) Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants. It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and peel. High demand for bromelain has resulted in gradual increases in bromelain production. These increases have led to the need for a bromelain production strategy that yields more purified bromelain at a lower cost and with fewer production steps. Previously, bromelain was purified by conventional centrifugation, ultrafiltration and lyophilisation. Recently, the development of more modern purification techniques such as gel filtration, ion exchange chromatography, affinity chromatography, aqueous two-phase extraction and reverse micelle chromatography has resulted in increased industrial bromelain production worldwide. In addition, recombinant DNA technology has emerged as an alternative strategy for producing large amounts of ultrapure bromelain. An up-to-date compilation of data regarding the commercialisation of bromelain in the clinical, pharmaceutical and industrial fields is provided in this review. Wiley 2016-11 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/16737/2/JSFA8122%20%281%29.pdf Aizi Nor Mazila, Ramli and Tuan Norsyalieza, Tuan Aznan and Rosli, Md. Illias (2016) Bromelain: from Production to Commercialisation. Journal of the Science of Food and Agriculture. pp. 1-10. http://onlinelibrary.wiley.com/doi/10.1002/jsfa.8122/full DOI 10.1002/jsfa.8122
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	S Agriculture (General)
spellingShingle	S Agriculture (General) Aizi Nor Mazila, Ramli Tuan Norsyalieza, Tuan Aznan Rosli, Md. Illias Bromelain: from Production to Commercialisation
description	Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants. It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and peel. High demand for bromelain has resulted in gradual increases in bromelain production. These increases have led to the need for a bromelain production strategy that yields more purified bromelain at a lower cost and with fewer production steps. Previously, bromelain was purified by conventional centrifugation, ultrafiltration and lyophilisation. Recently, the development of more modern purification techniques such as gel filtration, ion exchange chromatography, affinity chromatography, aqueous two-phase extraction and reverse micelle chromatography has resulted in increased industrial bromelain production worldwide. In addition, recombinant DNA technology has emerged as an alternative strategy for producing large amounts of ultrapure bromelain. An up-to-date compilation of data regarding the commercialisation of bromelain in the clinical, pharmaceutical and industrial fields is provided in this review.
format	Article
author	Aizi Nor Mazila, Ramli Tuan Norsyalieza, Tuan Aznan Rosli, Md. Illias
author_facet	Aizi Nor Mazila, Ramli Tuan Norsyalieza, Tuan Aznan Rosli, Md. Illias
author_sort	Aizi Nor Mazila, Ramli
title	Bromelain: from Production to Commercialisation
title_short	Bromelain: from Production to Commercialisation
title_full	Bromelain: from Production to Commercialisation
title_fullStr	Bromelain: from Production to Commercialisation
title_full_unstemmed	Bromelain: from Production to Commercialisation
title_sort	bromelain: from production to commercialisation
publisher	Wiley
publishDate	2016
url	http://umpir.ump.edu.my/id/eprint/16737/ http://umpir.ump.edu.my/id/eprint/16737/ http://umpir.ump.edu.my/id/eprint/16737/ http://umpir.ump.edu.my/id/eprint/16737/2/JSFA8122%20%281%29.pdf
first_indexed	2023-09-18T22:22:43Z
last_indexed	2023-09-18T22:22:43Z
_version_	1777415763488931840

Bromelain: from Production to Commercialisation

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