Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients

It has always been desirable for clinicians to ascertain whether glomerular filtration rate has recovered or still depressed at the bedside as increase in serum creatinine often indicates acute kidney injury to a clinician. In recent years, several clinical studies have developed mathematical models...

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Main Authors:	Fatimah, Dzaharudin, Azrina, Md Ralib, Mohd Basri, Mat Nor, Ummu Kulthum, Jamaludin
Format:	Conference or Workshop Item
Language:	English English
Published:	2017
Subjects:	Q Science (General) QA75 Electronic computers. Computer science R Medicine (General) RM Therapeutics. Pharmacology
Online Access:	http://umpir.ump.edu.my/id/eprint/16148/ http://umpir.ump.edu.my/id/eprint/16148/1/bare_conf.pdf http://umpir.ump.edu.my/id/eprint/16148/7/implementation%20of%20a%20prototype1.pdf

id	ump-16148
recordtype	eprints
spelling	ump-161482018-11-30T02:03:54Z http://umpir.ump.edu.my/id/eprint/16148/ Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients Fatimah, Dzaharudin Azrina, Md Ralib Mohd Basri, Mat Nor Ummu Kulthum, Jamaludin Q Science (General) QA75 Electronic computers. Computer science R Medicine (General) RM Therapeutics. Pharmacology It has always been desirable for clinicians to ascertain whether glomerular filtration rate has recovered or still depressed at the bedside as increase in serum creatinine often indicates acute kidney injury to a clinician. In recent years, several clinical studies have developed mathematical models to simulate the creatinine response to changes in glomerular filtration rate which includes the estimated glomerular filtration rate Chronic Kidney Disease Epidemiology Collaboration, the Chen-kinetic estimated GFR model and the modified Chen-Pianta-Endre-Pickering-Bukley-Pecke kinetic estimated GFR model. Another study also showed that the ratio of creatinine excretion rates to creatinine production rates may predict changes in plasma concentration. The aim of this study is to allow clinicians to gauge the performance of glomerular filtration rate estimation using the aforementioned equations and models to predict worsening of renal function, indicated by a low kinetic estimated glomerular filtration rate or creatinine production rates less than unity, or recovery of kidney function, indicated by high kinetic estimated glomerular filtration rate. In order to achieve this a mobile software is developed to aid data collection and calculation for the clinical study based on the aforementioned models. This paper summarises the implementation details of the native application development and presents the graphical user interface of the system in practice. 2017 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/16148/1/bare_conf.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/16148/7/implementation%20of%20a%20prototype1.pdf Fatimah, Dzaharudin and Azrina, Md Ralib and Mohd Basri, Mat Nor and Ummu Kulthum, Jamaludin (2017) Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients. In: IEEE-EMBS Conference on Biomedical Engineering and Sciences, 4-8 December 2016 , Kuala Lumpur, Malaysia. pp. 1-5..
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English
topic	Q Science (General) QA75 Electronic computers. Computer science R Medicine (General) RM Therapeutics. Pharmacology
spellingShingle	Q Science (General) QA75 Electronic computers. Computer science R Medicine (General) RM Therapeutics. Pharmacology Fatimah, Dzaharudin Azrina, Md Ralib Mohd Basri, Mat Nor Ummu Kulthum, Jamaludin Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients
description	It has always been desirable for clinicians to ascertain whether glomerular filtration rate has recovered or still depressed at the bedside as increase in serum creatinine often indicates acute kidney injury to a clinician. In recent years, several clinical studies have developed mathematical models to simulate the creatinine response to changes in glomerular filtration rate which includes the estimated glomerular filtration rate Chronic Kidney Disease Epidemiology Collaboration, the Chen-kinetic estimated GFR model and the modified Chen-Pianta-Endre-Pickering-Bukley-Pecke kinetic estimated GFR model. Another study also showed that the ratio of creatinine excretion rates to creatinine production rates may predict changes in plasma concentration. The aim of this study is to allow clinicians to gauge the performance of glomerular filtration rate estimation using the aforementioned equations and models to predict worsening of renal function, indicated by a low kinetic estimated glomerular filtration rate or creatinine production rates less than unity, or recovery of kidney function, indicated by high kinetic estimated glomerular filtration rate. In order to achieve this a mobile software is developed to aid data collection and calculation for the clinical study based on the aforementioned models. This paper summarises the implementation details of the native application development and presents the graphical user interface of the system in practice.
format	Conference or Workshop Item
author	Fatimah, Dzaharudin Azrina, Md Ralib Mohd Basri, Mat Nor Ummu Kulthum, Jamaludin
author_facet	Fatimah, Dzaharudin Azrina, Md Ralib Mohd Basri, Mat Nor Ummu Kulthum, Jamaludin
author_sort	Fatimah, Dzaharudin
title	Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients
title_short	Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients
title_full	Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients
title_fullStr	Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients
title_full_unstemmed	Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients
title_sort	implementation of a prototype glomerular filtration rate application to monitor creatinine kinetic dynamics in critically ill patients
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/16148/ http://umpir.ump.edu.my/id/eprint/16148/1/bare_conf.pdf http://umpir.ump.edu.my/id/eprint/16148/7/implementation%20of%20a%20prototype1.pdf
first_indexed	2023-09-18T22:21:33Z
last_indexed	2023-09-18T22:21:33Z
_version_	1777415690282598400

Implementation of a Prototype Glomerular Filtration Rate Application To Monitor Creatinine Kinetic Dynamics in Critically Ill Patients

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