Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose

The aim of the present study was to assess the biological properties of Dipteris conjugate and to identify its functional compounds. The methanolic leaves-extract (MLE) of D. conjugate at different concentrations 5 to 30 µg/ml were assessed for anti-bacterial activities by measuring inhibition zone...

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Main Authors:	Jarial, Rini, Singh, Lakhveer, Thakur , Sevta, Zularisam, A. W., Mimi Sakinah, A. M., Kanwar, S. S.
Format:	Conference or Workshop Item
Language:	English
Published:	Universiti Malaysia Pahang 2016
Subjects:	QR Microbiology
Online Access:	http://umpir.ump.edu.my/id/eprint/15759/ http://umpir.ump.edu.my/id/eprint/15759/ http://umpir.ump.edu.my/id/eprint/15759/1/P105%20pg775-782.pdf

id	ump-15759
recordtype	eprints
spelling	ump-157592019-10-03T07:51:26Z http://umpir.ump.edu.my/id/eprint/15759/ Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose Jarial, Rini Singh, Lakhveer Thakur , Sevta Zularisam, A. W. Mimi Sakinah, A. M. Kanwar, S. S. QR Microbiology The aim of the present study was to assess the biological properties of Dipteris conjugate and to identify its functional compounds. The methanolic leaves-extract (MLE) of D. conjugate at different concentrations 5 to 30 µg/ml were assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. MLE at a concentration of 25 µg/ml showed marked anti-bacterial activity against all bacterial strains (11-25 mm zone of inhibition) and was maximum against Staphylococcus aureus (25 mm). The MLE of had the best MIC values of 2.25 and 9.0 mg/ml against S.aureus and Enterobacter sp., respe D. conjugate actively. The MLE also possessed good antilipolytic activity (55%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (69%).The present study provided strong experimental evidences that the MLE of D.conjugate is not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities that might be beneficial in the body weight management. The results suggest that MLE of D. conjugate could potentially be employed in traditional medicine as they are rich in compounds with anti-oxidant, anti-microbial and anti-lipolytic properties. Universiti Malaysia Pahang 2016 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/15759/1/P105%20pg775-782.pdf Jarial, Rini and Singh, Lakhveer and Thakur , Sevta and Zularisam, A. W. and Mimi Sakinah, A. M. and Kanwar, S. S. (2016) Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose. In: Proceedings of The National Conference for Postgraduate Research (NCON-PGR 2016), 24-25 September 2016 , Universiti Malaysia Pahang (UMP), Pekan, Pahang. pp. 775-782.. http://ee.ump.edu.my/ncon/wp-content/uploads/2016/10/Proceeding-NCON-PGR-2016.zip
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Jarial, Rini Singh, Lakhveer Thakur , Sevta Zularisam, A. W. Mimi Sakinah, A. M. Kanwar, S. S. Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose
description	The aim of the present study was to assess the biological properties of Dipteris conjugate and to identify its functional compounds. The methanolic leaves-extract (MLE) of D. conjugate at different concentrations 5 to 30 µg/ml were assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. MLE at a concentration of 25 µg/ml showed marked anti-bacterial activity against all bacterial strains (11-25 mm zone of inhibition) and was maximum against Staphylococcus aureus (25 mm). The MLE of had the best MIC values of 2.25 and 9.0 mg/ml against S.aureus and Enterobacter sp., respe D. conjugate actively. The MLE also possessed good antilipolytic activity (55%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (69%).The present study provided strong experimental evidences that the MLE of D.conjugate is not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities that might be beneficial in the body weight management. The results suggest that MLE of D. conjugate could potentially be employed in traditional medicine as they are rich in compounds with anti-oxidant, anti-microbial and anti-lipolytic properties.
format	Conference or Workshop Item
author	Jarial, Rini Singh, Lakhveer Thakur , Sevta Zularisam, A. W. Mimi Sakinah, A. M. Kanwar, S. S.
author_facet	Jarial, Rini Singh, Lakhveer Thakur , Sevta Zularisam, A. W. Mimi Sakinah, A. M. Kanwar, S. S.
author_sort	Jarial, Rini
title	Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose
title_short	Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose
title_full	Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose
title_fullStr	Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose
title_full_unstemmed	Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose
title_sort	applications of fern dipteris conjugate in anti-bacterial and anti-lipolytic purpose
publisher	Universiti Malaysia Pahang
publishDate	2016
url	http://umpir.ump.edu.my/id/eprint/15759/ http://umpir.ump.edu.my/id/eprint/15759/ http://umpir.ump.edu.my/id/eprint/15759/1/P105%20pg775-782.pdf
first_indexed	2023-09-18T22:20:46Z
last_indexed	2023-09-18T22:20:46Z
_version_	1777415641178832896

Applications of Fern Dipteris Conjugate in Anti-bacterial and Anti-lipolytic Purpose

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