Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products

Tongkat Ali is most famous for its aphrodisiac property and has gained reputation worldwide. Due to this, Tongkat Ali products are in demand and can be obtained in various forms. The quality of these products is not often authenticated. As Malaysia is one of the major producing countries of Tongkat...

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Main Authors:	Aini Norhidayah, Mohamed, Jaya Vejayan, Palliah, M. M., Yusoff
Format:	Article
Language:	English English
Published:	Asian Network for Scientific Information 2015
Subjects:	T Technology (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/12633/ http://umpir.ump.edu.my/id/eprint/12633/ http://umpir.ump.edu.my/id/eprint/12633/ http://umpir.ump.edu.my/id/eprint/12633/1/fist-2015-jaya-Detection%20and%20Quantification%20of%20Eurycomanone.pdf http://umpir.ump.edu.my/id/eprint/12633/7/fist-2015-jaya-Detection%20and%20Quantification%20of%20Eurycomanone.pdf

id	ump-12633
recordtype	eprints
spelling	ump-126332018-07-26T03:28:57Z http://umpir.ump.edu.my/id/eprint/12633/ Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products Aini Norhidayah, Mohamed Jaya Vejayan, Palliah M. M., Yusoff T Technology (General) Tongkat Ali is most famous for its aphrodisiac property and has gained reputation worldwide. Due to this, Tongkat Ali products are in demand and can be obtained in various forms. The quality of these products is not often authenticated. As Malaysia is one of the major producing countries of Tongkat Ali products, this study adapted a method which is used to determine the quality of Tongkat Ali products in the market. The quality of those products is based on the level of eurycomanone, the major compound in Tongkat Ali and the level should be around 0.8-1.5 w/v (%). A total of 41 products were obtained internationally and from Malaysia, with different pharmaceutical dosage, single or combined formulation. Those products were analyzed for eurycomanone content using HPLC, C18 column with acetonitrile and water as the mobile phase. The result indicated that 24 of the products contained eurycomanone. Eleven out of the 24 products complied (0.84-8.48% w/v) with the criteria set by Malaysian Standard and 9 of the products even have the eurycomanone level above (1.6-8.48% w/v) the set criteria. It was observed no urycomanone was detected in some products even though the products have been registered with Malaysian herbal regulatory body, National Pharmaceutical Control Bureau (NPCB). In conclusion, this study suggests that the eurycomanone level should be utilized as a mandatory regulatory parameter for Tongkat Ali herbal preparation in the market besides the current parameters; microbial load and heavy metal contents alone Asian Network for Scientific Information 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/12633/1/fist-2015-jaya-Detection%20and%20Quantification%20of%20Eurycomanone.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/12633/7/fist-2015-jaya-Detection%20and%20Quantification%20of%20Eurycomanone.pdf Aini Norhidayah, Mohamed and Jaya Vejayan, Palliah and M. M., Yusoff (2015) Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products. Journal of Applied Sciences, 15 (7). pp. 999-1005. ISSN 1812-5654 (print); 1812-5662 (online) http://dx.doi.org/10.3923/jas.2015.999.1005 DOI: 10.3923/jas.2015.999.1005
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English
topic	T Technology (General)
spellingShingle	T Technology (General) Aini Norhidayah, Mohamed Jaya Vejayan, Palliah M. M., Yusoff Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products
description	Tongkat Ali is most famous for its aphrodisiac property and has gained reputation worldwide. Due to this, Tongkat Ali products are in demand and can be obtained in various forms. The quality of these products is not often authenticated. As Malaysia is one of the major producing countries of Tongkat Ali products, this study adapted a method which is used to determine the quality of Tongkat Ali products in the market. The quality of those products is based on the level of eurycomanone, the major compound in Tongkat Ali and the level should be around 0.8-1.5 w/v (%). A total of 41 products were obtained internationally and from Malaysia, with different pharmaceutical dosage, single or combined formulation. Those products were analyzed for eurycomanone content using HPLC, C18 column with acetonitrile and water as the mobile phase. The result indicated that 24 of the products contained eurycomanone. Eleven out of the 24 products complied (0.84-8.48% w/v) with the criteria set by Malaysian Standard and 9 of the products even have the eurycomanone level above (1.6-8.48% w/v) the set criteria. It was observed no urycomanone was detected in some products even though the products have been registered with Malaysian herbal regulatory body, National Pharmaceutical Control Bureau (NPCB). In conclusion, this study suggests that the eurycomanone level should be utilized as a mandatory regulatory parameter for Tongkat Ali herbal preparation in the market besides the current parameters; microbial load and heavy metal contents alone
format	Article
author	Aini Norhidayah, Mohamed Jaya Vejayan, Palliah M. M., Yusoff
author_facet	Aini Norhidayah, Mohamed Jaya Vejayan, Palliah M. M., Yusoff
author_sort	Aini Norhidayah, Mohamed
title	Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products
title_short	Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products
title_full	Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products
title_fullStr	Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products
title_full_unstemmed	Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products
title_sort	detection and quantification of eurycomanone levels in tongkat ali herbal products
publisher	Asian Network for Scientific Information
publishDate	2015
url	http://umpir.ump.edu.my/id/eprint/12633/ http://umpir.ump.edu.my/id/eprint/12633/ http://umpir.ump.edu.my/id/eprint/12633/ http://umpir.ump.edu.my/id/eprint/12633/1/fist-2015-jaya-Detection%20and%20Quantification%20of%20Eurycomanone.pdf http://umpir.ump.edu.my/id/eprint/12633/7/fist-2015-jaya-Detection%20and%20Quantification%20of%20Eurycomanone.pdf
first_indexed	2023-09-18T22:14:27Z
last_indexed	2023-09-18T22:14:27Z
_version_	1777415244160696320

Detection and Quantification of Eurycomanone Levels in Tongkat Ali Herbal Products

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