Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU

Currently, effective glycaemic control protocols consume significant nursing time, which may be unsustainable as the number of patients requiring control increases with increasing rates of diabetes. This paper investigates the safety and efficacy of basal insulin therapy as a means to reduce nurse w...

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Main Authors:	N. N., Razak, A. A., Razak, C. G., Pretty, N. H., Ahamad, F. M., Suhaimi, U., Jamaluddin
Format:	Article
Language:	English
Published:	Springer Singapore 2015
Subjects:	TJ Mechanical engineering and machinery
Online Access:	http://umpir.ump.edu.my/id/eprint/11577/ http://umpir.ump.edu.my/id/eprint/11577/ http://umpir.ump.edu.my/id/eprint/11577/ http://umpir.ump.edu.my/id/eprint/11577/1/Virtual%20Trial%20Protocol%20Analysis%20of%20Nursing%20Workload%20Intensity%20within%20ICU.pdf

id	ump-11577
recordtype	eprints
spelling	ump-115772016-04-12T04:11:49Z http://umpir.ump.edu.my/id/eprint/11577/ Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU N. N., Razak A. A., Razak C. G., Pretty N. H., Ahamad F. M., Suhaimi U., Jamaluddin TJ Mechanical engineering and machinery Currently, effective glycaemic control protocols consume significant nursing time, which may be unsustainable as the number of patients requiring control increases with increasing rates of diabetes. This paper investigates the safety and efficacy of basal insulin therapy as a means to reduce nurse workload associated with glycaemic control in intensive care patients with stress hyperglycaemia. Validated virtual trial simulations (N = 40 patients) of a successful glycaemic control protocol (SPRINT) using 1-2 hourly interventions and a modified version using 4 hour interventions augmented with basal insulin therapy using Glargine. An additional model was used to capture the kinetics of Glargine. Workload was assessed by counting the total number of interventions (BG measurements, changes to insulin and nutrition rates) per day. Glycaemic performance was assessed by time in the target band (4.4-7.0 mmol/L) and number of severe hypoglycaemic episodes (BG<2.2 mmol/L). Workload reduction is around 30% (p<0.001) due to basal insulin therapy. Glycaemic control performance was slightly reduced from 86% to 80% (p=0.006) time in the target band using basal insulin therapy and 4 hourly interventions. However, safety was maintained with 0 incidence hypoglycaemia. Basal insulin therapy enables glycaemic control protocols with reduced intervention frequency while maintaining performance and safety. Reduced intervention frequency directly translates into reduced nurse workload associated with glycaemic control. Springer Singapore 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/11577/1/Virtual%20Trial%20Protocol%20Analysis%20of%20Nursing%20Workload%20Intensity%20within%20ICU.pdf N. N., Razak and A. A., Razak and C. G., Pretty and N. H., Ahamad and F. M., Suhaimi and U., Jamaluddin (2015) Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU. International Conference for Innovation in Biomedical Engineering and Life Sciences, 56. pp. 294-297. ISSN 1680-0737 http://link.springer.com/chapter/10.1007/978-981-10-0266-3_62 DOI: 10.1007/978-981-10-0266-3_62
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TJ Mechanical engineering and machinery
spellingShingle	TJ Mechanical engineering and machinery N. N., Razak A. A., Razak C. G., Pretty N. H., Ahamad F. M., Suhaimi U., Jamaluddin Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU
description	Currently, effective glycaemic control protocols consume significant nursing time, which may be unsustainable as the number of patients requiring control increases with increasing rates of diabetes. This paper investigates the safety and efficacy of basal insulin therapy as a means to reduce nurse workload associated with glycaemic control in intensive care patients with stress hyperglycaemia. Validated virtual trial simulations (N = 40 patients) of a successful glycaemic control protocol (SPRINT) using 1-2 hourly interventions and a modified version using 4 hour interventions augmented with basal insulin therapy using Glargine. An additional model was used to capture the kinetics of Glargine. Workload was assessed by counting the total number of interventions (BG measurements, changes to insulin and nutrition rates) per day. Glycaemic performance was assessed by time in the target band (4.4-7.0 mmol/L) and number of severe hypoglycaemic episodes (BG<2.2 mmol/L). Workload reduction is around 30% (p<0.001) due to basal insulin therapy. Glycaemic control performance was slightly reduced from 86% to 80% (p=0.006) time in the target band using basal insulin therapy and 4 hourly interventions. However, safety was maintained with 0 incidence hypoglycaemia. Basal insulin therapy enables glycaemic control protocols with reduced intervention frequency while maintaining performance and safety. Reduced intervention frequency directly translates into reduced nurse workload associated with glycaemic control.
format	Article
author	N. N., Razak A. A., Razak C. G., Pretty N. H., Ahamad F. M., Suhaimi U., Jamaluddin
author_facet	N. N., Razak A. A., Razak C. G., Pretty N. H., Ahamad F. M., Suhaimi U., Jamaluddin
author_sort	N. N., Razak
title	Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU
title_short	Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU
title_full	Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU
title_fullStr	Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU
title_full_unstemmed	Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU
title_sort	virtual trial protocol analysis of nursing workload intensity within icu
publisher	Springer Singapore
publishDate	2015
url	http://umpir.ump.edu.my/id/eprint/11577/ http://umpir.ump.edu.my/id/eprint/11577/ http://umpir.ump.edu.my/id/eprint/11577/ http://umpir.ump.edu.my/id/eprint/11577/1/Virtual%20Trial%20Protocol%20Analysis%20of%20Nursing%20Workload%20Intensity%20within%20ICU.pdf
first_indexed	2023-09-18T22:12:29Z
last_indexed	2023-09-18T22:12:29Z
_version_	1777415119510175744

Virtual Trial Protocol Analysis of Nursing Workload Intensity within ICU

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