Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages

Xylitol is a five-carbon sugar alcohol that has many significant applications in the food, and pharmaceutical industries owing to its unique properties. Xylitol has proven its core value in reducing tooth decay and as sugar substitute for diabetes patient. In general, purification steps for producti...

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Main Author:	Wai Mun, Low
Format:	Undergraduates Project Papers
Language:	English English English
Published:	2015
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/11024/ http://umpir.ump.edu.my/id/eprint/11024/ http://umpir.ump.edu.my/id/eprint/11024/1/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29.pdf http://umpir.ump.edu.my/id/eprint/11024/2/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29%20CHAP%201.pdf http://umpir.ump.edu.my/id/eprint/11024/3/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29%20CHAP%203.pdf

id	ump-11024
recordtype	eprints
spelling	ump-110242015-11-02T01:09:11Z http://umpir.ump.edu.my/id/eprint/11024/ Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages Wai Mun, Low TP Chemical technology Xylitol is a five-carbon sugar alcohol that has many significant applications in the food, and pharmaceutical industries owing to its unique properties. Xylitol has proven its core value in reducing tooth decay and as sugar substitute for diabetes patient. In general, purification steps for production of fine product are of great interest in process engineering due to the complexity of the separation processes which leads to the major costing in production. Liquid-liquid extraction is a simple, time and energy saving separation method that employed to separate xylitol and impurities. Objective of this research is to optimize the conditions for purification of xylitol with ethyl acetate as solvent using response surface methodology in batch solvent extraction. Experiment design were done with one factor at time method to screen the significance of various factors, then RSM analysis was performed and experiments was conducted based on the suggested models. All the experiments were done in three replications to minimize systematic and instrument errors. OFAT results had shown that the time of extraction is not significant but the optimum conditions for volume ratio of sample to solvent is 1:5, and the number of multiple staging are 5 stages. Henceforth in RSM analysis, first factor was set to be the volume ratio of sample to solvent ranging from 1:2 to 1:6 and second factor was set to be the number of staging ranging from 2 to 6 stages. RSM analysis results that the overall model is valid, with correlation p-value of 0.002 (<0.05) with both two factors and factors’ squared proven to be significant to the response. The lack of fit value of 0.0003 for the model is significant. Feasibility study which is the xylitol extraction optimization using above suggested model by RSM produced from Meranti wood is validated. Results obtained from this research have demonstrated that both volume ratio and number of stages have significant effects in extraction process of xylitol purification and through careful optimization the downstream processing of commercial xylitol could be more effective 2015-01 Undergraduates Project Papers NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/11024/1/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/11024/2/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29%20CHAP%201.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/11024/3/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29%20CHAP%203.pdf Wai Mun, Low (2015) Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages. Faculty of Chemical & Natural Resources Engineering, Universiti Malaysia Pahang. http://iportal.ump.edu.my/lib/item?id=chamo:91297&theme=UMP2
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Wai Mun, Low Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
description	Xylitol is a five-carbon sugar alcohol that has many significant applications in the food, and pharmaceutical industries owing to its unique properties. Xylitol has proven its core value in reducing tooth decay and as sugar substitute for diabetes patient. In general, purification steps for production of fine product are of great interest in process engineering due to the complexity of the separation processes which leads to the major costing in production. Liquid-liquid extraction is a simple, time and energy saving separation method that employed to separate xylitol and impurities. Objective of this research is to optimize the conditions for purification of xylitol with ethyl acetate as solvent using response surface methodology in batch solvent extraction. Experiment design were done with one factor at time method to screen the significance of various factors, then RSM analysis was performed and experiments was conducted based on the suggested models. All the experiments were done in three replications to minimize systematic and instrument errors. OFAT results had shown that the time of extraction is not significant but the optimum conditions for volume ratio of sample to solvent is 1:5, and the number of multiple staging are 5 stages. Henceforth in RSM analysis, first factor was set to be the volume ratio of sample to solvent ranging from 1:2 to 1:6 and second factor was set to be the number of staging ranging from 2 to 6 stages. RSM analysis results that the overall model is valid, with correlation p-value of 0.002 (<0.05) with both two factors and factors’ squared proven to be significant to the response. The lack of fit value of 0.0003 for the model is significant. Feasibility study which is the xylitol extraction optimization using above suggested model by RSM produced from Meranti wood is validated. Results obtained from this research have demonstrated that both volume ratio and number of stages have significant effects in extraction process of xylitol purification and through careful optimization the downstream processing of commercial xylitol could be more effective
format	Undergraduates Project Papers
author	Wai Mun, Low
author_facet	Wai Mun, Low
author_sort	Wai Mun, Low
title	Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
title_short	Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
title_full	Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
title_fullStr	Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
title_full_unstemmed	Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
title_sort	process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages
publishDate	2015
url	http://umpir.ump.edu.my/id/eprint/11024/ http://umpir.ump.edu.my/id/eprint/11024/ http://umpir.ump.edu.my/id/eprint/11024/1/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29.pdf http://umpir.ump.edu.my/id/eprint/11024/2/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29%20CHAP%201.pdf http://umpir.ump.edu.my/id/eprint/11024/3/FKKSA%20-%20LOW%20WAI%20MUN%20%28CD8972%29%20CHAP%203.pdf
first_indexed	2023-09-18T22:11:19Z
last_indexed	2023-09-18T22:11:19Z
_version_	1777415046766264320

Process optimization for xylitol purification using liquid-liquid batch extraction : effect of volume ratios and number of stages

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