Malaysian nasal polyps: eosinophil or neutrophil-predominant

Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data...

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Main Authors:	Syuhada O, Shalini P, Lim, WK, Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain
Format:	Article
Language:	English
Published:	Fakulti Perubatan, UKM 2016
Online Access:	http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf

id	ukm-9788
recordtype	eprints
spelling	ukm-97882016-12-14T06:50:50Z http://journalarticle.ukm.my/9788/ Malaysian nasal polyps: eosinophil or neutrophil-predominant Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain, Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population. Fakulti Perubatan, UKM 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf Syuhada O, and Shalini P, and Lim, WK and Ammar A, and Suria Hayati Md Pauzi, and Aneeza Khairiyah Wan Hamizan, and Balwant Singh Gendeh, and Noraidah Masir, and Salina Husain, (2016) Malaysian nasal polyps: eosinophil or neutrophil-predominant. Medicine & Health, 11 (1). pp. 56-61. ISSN 1823-2140 http://www.medicineandhealthukm.com/toc/11/1
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population.
format	Article
author	Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain,
spellingShingle	Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain, Malaysian nasal polyps: eosinophil or neutrophil-predominant
author_facet	Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain,
author_sort	Syuhada O,
title	Malaysian nasal polyps: eosinophil or neutrophil-predominant
title_short	Malaysian nasal polyps: eosinophil or neutrophil-predominant
title_full	Malaysian nasal polyps: eosinophil or neutrophil-predominant
title_fullStr	Malaysian nasal polyps: eosinophil or neutrophil-predominant
title_full_unstemmed	Malaysian nasal polyps: eosinophil or neutrophil-predominant
title_sort	malaysian nasal polyps: eosinophil or neutrophil-predominant
publisher	Fakulti Perubatan, UKM
publishDate	2016
url	http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf
first_indexed	2023-09-18T19:55:43Z
last_indexed	2023-09-18T19:55:43Z
_version_	1777406515847626752

Malaysian nasal polyps: eosinophil or neutrophil-predominant

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