Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats

As a natural anti-oxidant source, Tualang honey, produced by wild bees nesting on the Tualang tree (Koompassia excelsa) is expected to have positive influence on health, including memory. This study investigated the effect of Tualang honey on the cell count of memory formation related hippocampal...

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Main Authors:	Mohd Amiruddin Kamarulzaidi, M. Y. Zulkifli Mohd. Yusoff, Abdul Majid Mohamed, Durriyyah Sharifah Hasan Adli
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2016
Online Access:	http://journalarticle.ukm.my/9675/ http://journalarticle.ukm.my/9675/ http://journalarticle.ukm.my/9675/1/08_Mohd_Amiruddin_Kamarulzaidi.pdf

id	ukm-9675
recordtype	eprints
spelling	ukm-96752016-12-14T06:50:31Z http://journalarticle.ukm.my/9675/ Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats Mohd Amiruddin Kamarulzaidi, M. Y. Zulkifli Mohd. Yusoff, Abdul Majid Mohamed, Durriyyah Sharifah Hasan Adli, As a natural anti-oxidant source, Tualang honey, produced by wild bees nesting on the Tualang tree (Koompassia excelsa) is expected to have positive influence on health, including memory. This study investigated the effect of Tualang honey on the cell count of memory formation related hippocampal pyramidal neuron and on spatial memory performance (SMP) of rats using the radial arm maze (RAM). Sprague Dawley male rats (n=24), 7-8 weeks old were divided into two groups; experimental group group force-fed 1 mL/100 g body weight with 70% honey (HG); and the control group with 0.9% saline (CG) for 12 weeks. Nissl staining technique (with cresyl violet) was employed for neurohistological analysis of the hippocampal tissue. Six randomly selected rats from each group were used for the neuronal soma counting of pyramidal cell layer CA1, CA3a and CA3c regions. Two-way ANOVA analysis showed positively significant differences between treatment and control groups for SMP comparison of working memory and reference memory components, as well as the number of pyramidal neurons. Hence, this positive effects of Tualang honey, as demonstrated behaviorally and neurohistologically, supported report that Tualang honey could improve memory and deter hippocampal morphological impairments; possibly due to its high anti-oxidant properties. Universiti Kebangsaan Malaysia 2016-02 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9675/1/08_Mohd_Amiruddin_Kamarulzaidi.pdf Mohd Amiruddin Kamarulzaidi, and M. Y. Zulkifli Mohd. Yusoff, and Abdul Majid Mohamed, and Durriyyah Sharifah Hasan Adli, (2016) Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats. Sains Malaysiana, 45 (2). pp. 215-220. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid45bil2_2016/KandunganJilid45Bil2_2016.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	As a natural anti-oxidant source, Tualang honey, produced by wild bees nesting on the Tualang tree (Koompassia excelsa) is expected to have positive influence on health, including memory. This study investigated the effect of Tualang honey on the cell count of memory formation related hippocampal pyramidal neuron and on spatial memory performance (SMP) of rats using the radial arm maze (RAM). Sprague Dawley male rats (n=24), 7-8 weeks old were divided into two groups; experimental group group force-fed 1 mL/100 g body weight with 70% honey (HG); and the control group with 0.9% saline (CG) for 12 weeks. Nissl staining technique (with cresyl violet) was employed for neurohistological analysis of the hippocampal tissue. Six randomly selected rats from each group were used for the neuronal soma counting of pyramidal cell layer CA1, CA3a and CA3c regions. Two-way ANOVA analysis showed positively significant differences between treatment and control groups for SMP comparison of working memory and reference memory components, as well as the number of pyramidal neurons. Hence, this positive effects of Tualang honey, as demonstrated behaviorally and neurohistologically, supported report that Tualang honey could improve memory and deter hippocampal morphological impairments; possibly due to its high anti-oxidant properties.
format	Article
author	Mohd Amiruddin Kamarulzaidi, M. Y. Zulkifli Mohd. Yusoff, Abdul Majid Mohamed, Durriyyah Sharifah Hasan Adli,
spellingShingle	Mohd Amiruddin Kamarulzaidi, M. Y. Zulkifli Mohd. Yusoff, Abdul Majid Mohamed, Durriyyah Sharifah Hasan Adli, Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
author_facet	Mohd Amiruddin Kamarulzaidi, M. Y. Zulkifli Mohd. Yusoff, Abdul Majid Mohamed, Durriyyah Sharifah Hasan Adli,
author_sort	Mohd Amiruddin Kamarulzaidi,
title	Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
title_short	Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
title_full	Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
title_fullStr	Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
title_full_unstemmed	Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
title_sort	tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats
publisher	Universiti Kebangsaan Malaysia
publishDate	2016
url	http://journalarticle.ukm.my/9675/ http://journalarticle.ukm.my/9675/ http://journalarticle.ukm.my/9675/1/08_Mohd_Amiruddin_Kamarulzaidi.pdf
first_indexed	2023-09-18T19:55:23Z
last_indexed	2023-09-18T19:55:23Z
_version_	1777406494800609280

Tualang honey consumption enhanced hippocampal pyramidal count and spatial memory performance of adult male rats

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