Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral

Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral

This study was carried out to investigate the influence of storage time, storage temperature and oxygen on degradation of ascorbic acid in parenteral nutrition admixture (PNA). The PNAs were prepared in ethyl vinyl acetate (EVA) bags based on basic parenteral nutrition regimen. The PNAs were prepare...

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Main Authors: Ahmad Fuad Shamsuddin, Risydan Mohamad, Bukhori Abu Bakar
Format: Article
Language:English
Published: penerbit ukm 2004
Online Access:http://journalarticle.ukm.my/961/
http://journalarticle.ukm.my/961/
http://journalarticle.ukm.my/961/1/jurnal17.pdf
id ukm-961
recordtype eprints
spelling ukm-9612016-12-14T06:28:25Z http://journalarticle.ukm.my/961/ Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral Ahmad Fuad Shamsuddin, Risydan Mohamad, Bukhori Abu Bakar, This study was carried out to investigate the influence of storage time, storage temperature and oxygen on degradation of ascorbic acid in parenteral nutrition admixture (PNA). The PNAs were prepared in ethyl vinyl acetate (EVA) bags based on basic parenteral nutrition regimen. The PNAs were prepared aseptically in a laminar flow hood. Storage temperature was set at 25, 30, 35 and 40°C. Samples containing air (oxygen) and air-free were taken from EVA bags at 0, 6, 12, 24 and 30 hrs. PNA samples (containing ascorbic acid) were analysed by High Performance Liquid Chromatography (HPLC). Standard calibration curve and retention time of ascorbic acid were determined prior to analysis of samples. The study showed a significant decrease of ascorbic acid content in both PNAs containing air and air-free in relation to the increase in storage time and temperature (p < 0.05). The decrease of ascorbic acid content in PNAs with air was higher compared to the ones air-free. In conclusion, the degradation of ascorbic acid in PNAs is influenced by storage time and temperature as well as the presence of air. penerbit ukm 2004 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/961/1/jurnal17.pdf Ahmad Fuad Shamsuddin, and Risydan Mohamad, and Bukhori Abu Bakar, (2004) Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral. Jurnal Sains Kesihatan Malaysia, 2 (1). pp. 1-8. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal
repository_type Digital Repository
institution_category Local University
institution Universiti Kebangasaan Malaysia
building UKM Institutional Repository
collection Online Access
language English
description This study was carried out to investigate the influence of storage time, storage temperature and oxygen on degradation of ascorbic acid in parenteral nutrition admixture (PNA). The PNAs were prepared in ethyl vinyl acetate (EVA) bags based on basic parenteral nutrition regimen. The PNAs were prepared aseptically in a laminar flow hood. Storage temperature was set at 25, 30, 35 and 40°C. Samples containing air (oxygen) and air-free were taken from EVA bags at 0, 6, 12, 24 and 30 hrs. PNA samples (containing ascorbic acid) were analysed by High Performance Liquid Chromatography (HPLC). Standard calibration curve and retention time of ascorbic acid were determined prior to analysis of samples. The study showed a significant decrease of ascorbic acid content in both PNAs containing air and air-free in relation to the increase in storage time and temperature (p < 0.05). The decrease of ascorbic acid content in PNAs with air was higher compared to the ones air-free. In conclusion, the degradation of ascorbic acid in PNAs is influenced by storage time and temperature as well as the presence of air.
format Article
author Ahmad Fuad Shamsuddin,
Risydan Mohamad,
Bukhori Abu Bakar,
spellingShingle Ahmad Fuad Shamsuddin,
Risydan Mohamad,
Bukhori Abu Bakar,
Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
author_facet Ahmad Fuad Shamsuddin,
Risydan Mohamad,
Bukhori Abu Bakar,
author_sort Ahmad Fuad Shamsuddin,
title Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
title_short Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
title_full Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
title_fullStr Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
title_full_unstemmed Kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
title_sort kajian pendegradan asid askorbik dalam admikstur pemakanan parenteral
publisher penerbit ukm
publishDate 2004
url http://journalarticle.ukm.my/961/
http://journalarticle.ukm.my/961/
http://journalarticle.ukm.my/961/1/jurnal17.pdf
first_indexed 2023-09-18T19:32:00Z
last_indexed 2023-09-18T19:32:00Z
_version_ 1777405023561449472

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