Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy
A 37-year-old Malay woman presented with progressive deterioration in vision and was diagnosed with advanced proliferative diabetic retinopathy with neovascular glaucoma. Intravitreal ranibizumab injection (an anti-vascular endothelial growth factor) was administered prior to vitrectomy. Slit lamp a...
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Department of Surgery, UKM Medical Centre
2011
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| Online Access: | http://journalarticle.ukm.my/931/ http://journalarticle.ukm.my/931/ http://journalarticle.ukm.my/931/1/Dramatic_Response_of_Iris_and_Retinal.pdf |
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ukm-9312016-12-14T06:28:21Z http://journalarticle.ukm.my/931/ Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy Malisa A, Mae-Lynn CB, A 37-year-old Malay woman presented with progressive deterioration in vision and was diagnosed with advanced proliferative diabetic retinopathy with neovascular glaucoma. Intravitreal ranibizumab injection (an anti-vascular endothelial growth factor) was administered prior to vitrectomy. Slit lamp assessment 2 days post-injection revealed significant regression of both iris and retinal neovascularisation. This resulted in adequate reduction of intra-ocular pressure prior to surgery. In addition, the regression of retinal vessels reduced the risk of intra-operative haemorrhage, thus aiding the surgical excision of the fibrovascular membranes. Periodic post-operative assessment in the first 3 weeks showed minimal inflammation and no recurrence of vitreous haemorrhage. This case illustrates that intravitreal ranibizumab has a role as an adjunct therapy prior to diabetic vitrectomy to significantly reduce the risk of intra-ocular haemorrhage. Department of Surgery, UKM Medical Centre 2011-04-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/931/1/Dramatic_Response_of_Iris_and_Retinal.pdf Malisa A, and Mae-Lynn CB, (2011) Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy. Journal of Surgical Academia, 1 (1). pp. 67-70. ISSN 2231-7481 http://jsurgacad.com/ |
| repository_type |
Digital Repository |
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Local University |
| institution |
Universiti Kebangasaan Malaysia |
| building |
UKM Institutional Repository |
| collection |
Online Access |
| language |
English |
| description |
A 37-year-old Malay woman presented with progressive deterioration in vision and was diagnosed with advanced proliferative diabetic retinopathy with neovascular glaucoma. Intravitreal ranibizumab injection (an anti-vascular endothelial growth factor) was administered prior to vitrectomy. Slit lamp assessment 2 days post-injection revealed significant regression of both iris and retinal neovascularisation. This resulted in adequate reduction of intra-ocular pressure prior to surgery. In addition, the regression of retinal vessels reduced the risk of intra-operative haemorrhage, thus aiding the surgical excision of the fibrovascular membranes. Periodic post-operative assessment in the first 3 weeks showed minimal inflammation and no recurrence of vitreous haemorrhage. This case illustrates that intravitreal ranibizumab has a role as an adjunct therapy prior to diabetic vitrectomy to significantly reduce the risk of intra-ocular haemorrhage. |
| format |
Article |
| author |
Malisa A, Mae-Lynn CB, |
| spellingShingle |
Malisa A, Mae-Lynn CB, Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| author_facet |
Malisa A, Mae-Lynn CB, |
| author_sort |
Malisa A, |
| title |
Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| title_short |
Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| title_full |
Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| title_fullStr |
Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| title_full_unstemmed |
Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| title_sort |
dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy |
| publisher |
Department of Surgery, UKM Medical Centre |
| publishDate |
2011 |
| url |
http://journalarticle.ukm.my/931/ http://journalarticle.ukm.my/931/ http://journalarticle.ukm.my/931/1/Dramatic_Response_of_Iris_and_Retinal.pdf |
| first_indexed |
2023-09-18T19:31:57Z |
| last_indexed |
2023-09-18T19:31:57Z |
| _version_ |
1777405019783430144 |