The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men

Bone turnover markers (BTMs) are useful in the assessment of bone health status. However, the infl uence of age, ethnicity and body anthropometry on the level of BTMs in men remains understudied. This study aimed to determine the influence of these factors on the level of BTM, namely osteoclacin (OC...

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Main Authors:	Ima Nirwana Soelaiman, Kok, Yong Chin, Isa Naina Mohamed, Wan Zurinah Wan Ngah
Format:	Article
Language:	English
Published:	penerbit ukm 2014
Subjects:	RA Public aspects of medicine
Online Access:	http://journalarticle.ukm.my/7478/ http://journalarticle.ukm.my/7478/ http://journalarticle.ukm.my/7478/1/The_Influence_of_Age%2C_Ethnicity_and_Body_Anthropometry.pdf

id	ukm-7478
recordtype	eprints
spelling	ukm-74782016-12-14T06:44:13Z http://journalarticle.ukm.my/7478/ The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men Ima Nirwana Soelaiman, Kok, Yong Chin Isa Naina Mohamed, Wan Zurinah Wan Ngah, RA Public aspects of medicine Bone turnover markers (BTMs) are useful in the assessment of bone health status. However, the infl uence of age, ethnicity and body anthropometry on the level of BTMs in men remains understudied. This study aimed to determine the influence of these factors on the level of BTM, namely osteoclacin (OC) and C-terminal telopeptides of type 1 collagen (CTX-1) among Malay and Chinese men (N = 407) aged 20 years and above in Klang Valley. The subjects were recruited using purposive sampling method. Their height, body weight and body mass index were measured. Their blood was collected in the morning for serum OC and CTX-1 analysis using enzyme-linked immunoasorbent assays. Results showed that OC and CTX-1 levels were significantly higher in Malay compared to Chinese men (p < 0.05). Highest levels of OC and CTX-1 were observed in men aged 20-29 years, while the lowest levels were found among men aged 30-39 years (p < 0.005). No significant diff erences in the levels of both markers were found between the older men and those aged 30-39 years (p > 0.005). There were significant and negative correlations between OC and body mass index and weight, which were significant for men aged 20-39 years only (p < 0.05). Body anthropometry was not correlated with CTX-1 level in men (p > 0.05). As a conclusion, levels of BTMs in Malaysian men could be infl uenced by age, ethnicity and body anthropometry. Thus, these factors should be taken into consideration in the evaluation of bone health status of men using BTMs. penerbit ukm 2014 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/7478/1/The_Influence_of_Age%2C_Ethnicity_and_Body_Anthropometry.pdf Ima Nirwana Soelaiman, and Kok, Yong Chin and Isa Naina Mohamed, and Wan Zurinah Wan Ngah, (2014) The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men. Jurnal Sains Kesihatan Malaysia, 12 (1). pp. 7-13. ISSN 1675-8161 http://ejournal.ukm.my/jskm/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
topic	RA Public aspects of medicine
spellingShingle	RA Public aspects of medicine Ima Nirwana Soelaiman, Kok, Yong Chin Isa Naina Mohamed, Wan Zurinah Wan Ngah, The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
description	Bone turnover markers (BTMs) are useful in the assessment of bone health status. However, the infl uence of age, ethnicity and body anthropometry on the level of BTMs in men remains understudied. This study aimed to determine the influence of these factors on the level of BTM, namely osteoclacin (OC) and C-terminal telopeptides of type 1 collagen (CTX-1) among Malay and Chinese men (N = 407) aged 20 years and above in Klang Valley. The subjects were recruited using purposive sampling method. Their height, body weight and body mass index were measured. Their blood was collected in the morning for serum OC and CTX-1 analysis using enzyme-linked immunoasorbent assays. Results showed that OC and CTX-1 levels were significantly higher in Malay compared to Chinese men (p < 0.05). Highest levels of OC and CTX-1 were observed in men aged 20-29 years, while the lowest levels were found among men aged 30-39 years (p < 0.005). No significant diff erences in the levels of both markers were found between the older men and those aged 30-39 years (p > 0.005). There were significant and negative correlations between OC and body mass index and weight, which were significant for men aged 20-39 years only (p < 0.05). Body anthropometry was not correlated with CTX-1 level in men (p > 0.05). As a conclusion, levels of BTMs in Malaysian men could be infl uenced by age, ethnicity and body anthropometry. Thus, these factors should be taken into consideration in the evaluation of bone health status of men using BTMs.
format	Article
author	Ima Nirwana Soelaiman, Kok, Yong Chin Isa Naina Mohamed, Wan Zurinah Wan Ngah,
author_facet	Ima Nirwana Soelaiman, Kok, Yong Chin Isa Naina Mohamed, Wan Zurinah Wan Ngah,
author_sort	Ima Nirwana Soelaiman,
title	The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_short	The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_full	The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_fullStr	The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_full_unstemmed	The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_sort	influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type i collagen in men
publisher	penerbit ukm
publishDate	2014
url	http://journalarticle.ukm.my/7478/ http://journalarticle.ukm.my/7478/ http://journalarticle.ukm.my/7478/1/The_Influence_of_Age%2C_Ethnicity_and_Body_Anthropometry.pdf
first_indexed	2023-09-18T19:49:49Z
last_indexed	2023-09-18T19:49:49Z
_version_	1777406144108560384

The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men

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