Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study

Mild cognitive impairment (MCI) is associated with significant morbidity, especially in the development of Alzheimer’s disease and also related to nutritional factors. A pilot study was carried out to determine antioxidant intake and its relation with MCI among elderly people aged between 60 and 74...

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Main Authors:	Sher, Hui Wong, Roslee Rajikan, Suzana Shahar, Noor Aini Mohd Yusoff, Lai, Kuan Lee, Safiyyah Abdul Aziz, Noor Ibrahim Mohd Sakian, Srijit Das
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2010
Online Access:	http://journalarticle.ukm.my/7391/ http://journalarticle.ukm.my/7391/ http://journalarticle.ukm.my/7391/2/01_Md_Yeaminhossain.pdf

id	ukm-7391
recordtype	eprints
spelling	ukm-73912016-12-14T06:43:56Z http://journalarticle.ukm.my/7391/ Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study Sher, Hui Wong Roslee Rajikan, Suzana Shahar, Noor Aini Mohd Yusoff, Lai, Kuan Lee Safiyyah Abdul Aziz, Noor Ibrahim Mohd Sakian, Srijit Das, Mild cognitive impairment (MCI) is associated with significant morbidity, especially in the development of Alzheimer’s disease and also related to nutritional factors. A pilot study was carried out to determine antioxidant intake and its relation with MCI among elderly people aged between 60 and 74 years in Klang Valley. Subjects were interviewed to obtain socio-demography data and functional status was evaluated using the Instrumental Activities of Daily Living (IADL). Data on food intake was assessed using the diet history questionnaire and food frequency questionnaire, whilst the Geriatric Depression Scale (GDS) was used to assess depression level. A combination of tests was used to assess cognitive decline, which are Mini-mental State Examination (MMSE), Clock Drawing Test (CDT), and Dementia Rating Scale (DRS). Out of 84 elderly recruited, 70 completed all parts of the study (response rate 83.3%). Mean vitamin E intake was less than the Malaysian RNI (50.0% of RNI for men and 43.0% for women). The incidence of amnestic-MCI (aMCI) was 15.7% among the respondents, while 32.8% were depressed. After adjustment for educational background, beta-carotene intake was found to be significantly (β=0.325, p<0.05) correlated to cognitive impairment based on CDT scores. The intake levels of antioxidants among subjects were unsatisfactory and beta-carotene intake was related to poor cognitive status based on CDT. Universiti Kebangsaan Malaysia 2010-08 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/7391/2/01_Md_Yeaminhossain.pdf Sher, Hui Wong and Roslee Rajikan, and Suzana Shahar, and Noor Aini Mohd Yusoff, and Lai, Kuan Lee and Safiyyah Abdul Aziz, and Noor Ibrahim Mohd Sakian, and Srijit Das, (2010) Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study. Sains Malaysiana, 39 (4). pp. 689-696. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol39num4_2010/contentsVol39num4_2010.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Mild cognitive impairment (MCI) is associated with significant morbidity, especially in the development of Alzheimer’s disease and also related to nutritional factors. A pilot study was carried out to determine antioxidant intake and its relation with MCI among elderly people aged between 60 and 74 years in Klang Valley. Subjects were interviewed to obtain socio-demography data and functional status was evaluated using the Instrumental Activities of Daily Living (IADL). Data on food intake was assessed using the diet history questionnaire and food frequency questionnaire, whilst the Geriatric Depression Scale (GDS) was used to assess depression level. A combination of tests was used to assess cognitive decline, which are Mini-mental State Examination (MMSE), Clock Drawing Test (CDT), and Dementia Rating Scale (DRS). Out of 84 elderly recruited, 70 completed all parts of the study (response rate 83.3%). Mean vitamin E intake was less than the Malaysian RNI (50.0% of RNI for men and 43.0% for women). The incidence of amnestic-MCI (aMCI) was 15.7% among the respondents, while 32.8% were depressed. After adjustment for educational background, beta-carotene intake was found to be significantly (β=0.325, p<0.05) correlated to cognitive impairment based on CDT scores. The intake levels of antioxidants among subjects were unsatisfactory and beta-carotene intake was related to poor cognitive status based on CDT.
format	Article
author	Sher, Hui Wong Roslee Rajikan, Suzana Shahar, Noor Aini Mohd Yusoff, Lai, Kuan Lee Safiyyah Abdul Aziz, Noor Ibrahim Mohd Sakian, Srijit Das,
spellingShingle	Sher, Hui Wong Roslee Rajikan, Suzana Shahar, Noor Aini Mohd Yusoff, Lai, Kuan Lee Safiyyah Abdul Aziz, Noor Ibrahim Mohd Sakian, Srijit Das, Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study
author_facet	Sher, Hui Wong Roslee Rajikan, Suzana Shahar, Noor Aini Mohd Yusoff, Lai, Kuan Lee Safiyyah Abdul Aziz, Noor Ibrahim Mohd Sakian, Srijit Das,
author_sort	Sher, Hui Wong
title	Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study
title_short	Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study
title_full	Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study
title_fullStr	Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study
title_full_unstemmed	Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study
title_sort	antioxidant intake and mild cognitive impairment among elderly people in klang valley: a pilot study
publisher	Universiti Kebangsaan Malaysia
publishDate	2010
url	http://journalarticle.ukm.my/7391/ http://journalarticle.ukm.my/7391/ http://journalarticle.ukm.my/7391/2/01_Md_Yeaminhossain.pdf
first_indexed	2023-09-18T19:49:34Z
last_indexed	2023-09-18T19:49:34Z
_version_	1777406128570761216

Antioxidant intake and mild cognitive impairment among elderly people in Klang Valley: a pilot study

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