Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment

During orthodontic treatment, the progress of tooth movements can be classified into four stages, i.e. activation (related to tissue inflammation or cells’ death), resorption, reversal and restructuring of new bones. Tooth movement is related to metabolic changes around the mouth. The objective of t...

Full description

Bibliographic Details
Main Authors:	Shahrul Hisham Zainal Ariffin, Mohd Faiz Ellias, Rohaya Megat Abdul Wahab, Yosni Bakar, Sahidan Senafi
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2010
Online Access:	http://journalarticle.ukm.my/7350/ http://journalarticle.ukm.my/7350/ http://journalarticle.ukm.my/7350/1/01_Md_Yeaminhossain.pdf

id	ukm-7350
recordtype	eprints
spelling	ukm-73502016-12-14T06:43:49Z http://journalarticle.ukm.my/7350/ Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment Shahrul Hisham Zainal Ariffin, Mohd Faiz Ellias, Rohaya Megat Abdul Wahab, Yosni Bakar, Sahidan Senafi, During orthodontic treatment, the progress of tooth movements can be classified into four stages, i.e. activation (related to tissue inflammation or cells’ death), resorption, reversal and restructuring of new bones. Tooth movement is related to metabolic changes around the mouth. The objective of this study was to determine enzymes profiles from patient’s saliva during orthodontic tooth movement, i.e., lactate dehydrogenase (LDH) for inflammation, tartrate resistant acid phosphatase (TRAP) for bone resorption and alkaline phosphatase (ALP) for bone formation. Saliva samples were collected from 6 orthodontic patients. Activities of all enzymes were measured before placement of orthodontic fixed appliances (normal activity) followed with day 3, 7, 10, 14, 17, 21, 24, 28 and 31 after the braces were activated. All enzymes (LDH, TRAP and ALP) showed significantly (p≤0.05) higher specific activities as compared to normal. LDH showed the increment at the early phase of treatment (day 3,7 and 10), TRAP at day 14 and 17 followed by ALP at day 17, 21 and 24. As a conclusion, the profiles of enzymes activities showed that inflammation occured during early phase of treatment followed by bone resorption and bone formation. In addition, the inflammations, resorption and bone formation phases in orthodontic treatment were found to be completed within 24 days. Universiti Kebangsaan Malaysia 2010 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/7350/1/01_Md_Yeaminhossain.pdf Shahrul Hisham Zainal Ariffin, and Mohd Faiz Ellias, and Rohaya Megat Abdul Wahab, and Yosni Bakar, and Sahidan Senafi, (2010) Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment. Sains Malaysiana, 39 (3). pp. 405-412. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol39num3_2010/contentsVol39num3_2010.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	During orthodontic treatment, the progress of tooth movements can be classified into four stages, i.e. activation (related to tissue inflammation or cells’ death), resorption, reversal and restructuring of new bones. Tooth movement is related to metabolic changes around the mouth. The objective of this study was to determine enzymes profiles from patient’s saliva during orthodontic tooth movement, i.e., lactate dehydrogenase (LDH) for inflammation, tartrate resistant acid phosphatase (TRAP) for bone resorption and alkaline phosphatase (ALP) for bone formation. Saliva samples were collected from 6 orthodontic patients. Activities of all enzymes were measured before placement of orthodontic fixed appliances (normal activity) followed with day 3, 7, 10, 14, 17, 21, 24, 28 and 31 after the braces were activated. All enzymes (LDH, TRAP and ALP) showed significantly (p≤0.05) higher specific activities as compared to normal. LDH showed the increment at the early phase of treatment (day 3,7 and 10), TRAP at day 14 and 17 followed by ALP at day 17, 21 and 24. As a conclusion, the profiles of enzymes activities showed that inflammation occured during early phase of treatment followed by bone resorption and bone formation. In addition, the inflammations, resorption and bone formation phases in orthodontic treatment were found to be completed within 24 days.
format	Article
author	Shahrul Hisham Zainal Ariffin, Mohd Faiz Ellias, Rohaya Megat Abdul Wahab, Yosni Bakar, Sahidan Senafi,
spellingShingle	Shahrul Hisham Zainal Ariffin, Mohd Faiz Ellias, Rohaya Megat Abdul Wahab, Yosni Bakar, Sahidan Senafi, Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
author_facet	Shahrul Hisham Zainal Ariffin, Mohd Faiz Ellias, Rohaya Megat Abdul Wahab, Yosni Bakar, Sahidan Senafi,
author_sort	Shahrul Hisham Zainal Ariffin,
title	Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
title_short	Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
title_full	Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
title_fullStr	Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
title_full_unstemmed	Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
title_sort	profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment
publisher	Universiti Kebangsaan Malaysia
publishDate	2010
url	http://journalarticle.ukm.my/7350/ http://journalarticle.ukm.my/7350/ http://journalarticle.ukm.my/7350/1/01_Md_Yeaminhossain.pdf
first_indexed	2023-09-18T19:49:29Z
last_indexed	2023-09-18T19:49:29Z
_version_	1777406122675666944

Profiles of lactate dehydrogenase, tartrate resistant acid phosphatase and alkaline photophatase in saliva during orthodontic treatment

Similar Items