Peninsular Malaysia’s Negrito orang Asli and its theory of African origin

Negritos of Peninsular Malaysia have physical features which strongly resemble the African pygmies rather than any of the other main South East Asian ethnic groups. In addition, their features are also completely different from the two other large sub-groups of the Peninsular Malaysia Orang Asli, i....

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Main Authors:	Endom Ismail, Farahnaz Amini, Shairah Abdul Razak, Husna Mohd Zaini, Reza Farhour, Bin Alwi Zilfalil
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2013
Online Access:	http://journalarticle.ukm.my/6298/ http://journalarticle.ukm.my/6298/ http://journalarticle.ukm.my/6298/1/05_Endom_Ismil_.pdf

id	ukm-6298
recordtype	eprints
spelling	ukm-62982016-12-14T06:40:46Z http://journalarticle.ukm.my/6298/ Peninsular Malaysia’s Negrito orang Asli and its theory of African origin Endom Ismail, Farahnaz Amini, Shairah Abdul Razak, Husna Mohd Zaini, Reza Farhour, Bin Alwi Zilfalil, Negritos of Peninsular Malaysia have physical features which strongly resemble the African pygmies rather than any of the other main South East Asian ethnic groups. In addition, their features are also completely different from the two other large sub-groups of the Peninsular Malaysia Orang Asli, i.e. Senoi and Proto-Malay. In this study, we genetically screened three African-specific markers, Glucose-6 Phosphate Dehydrogenase (G6PD) gene PvuII Type 2 polymorphism and A- mutation; and Sickle Cell trait in 103 unrelated individuals with G6PD deficiency. None of the Negritos’ samples carried A- and Sickle cell mutations but all males and females have the PvuII Type 2 polymorphism. The same results were seen in all DNA samples of the Malaysian’s Malay, Chinese and Indians. Additionally, all females in this study were homozygous for PvuII Type 2 polymorphism. Thus, we concluded that this polymorphism is widespread in all Malaysian population and is not unique to just Africans. However, these findings indicated that the polymorphism was widely conserved and can be used to study the African descendant in any world population hitherto supporting the ‘Out of Africa’ theory. Universiti Kebangsaan Malaysia 2013-07 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/6298/1/05_Endom_Ismil_.pdf Endom Ismail, and Farahnaz Amini, and Shairah Abdul Razak, and Husna Mohd Zaini, and Reza Farhour, and Bin Alwi Zilfalil, (2013) Peninsular Malaysia’s Negrito orang Asli and its theory of African origin. Sains Malaysiana, 42 (7). pp. 921-926. ISSN 0126-6039 http://www.ukm.my/jsm/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Negritos of Peninsular Malaysia have physical features which strongly resemble the African pygmies rather than any of the other main South East Asian ethnic groups. In addition, their features are also completely different from the two other large sub-groups of the Peninsular Malaysia Orang Asli, i.e. Senoi and Proto-Malay. In this study, we genetically screened three African-specific markers, Glucose-6 Phosphate Dehydrogenase (G6PD) gene PvuII Type 2 polymorphism and A- mutation; and Sickle Cell trait in 103 unrelated individuals with G6PD deficiency. None of the Negritos’ samples carried A- and Sickle cell mutations but all males and females have the PvuII Type 2 polymorphism. The same results were seen in all DNA samples of the Malaysian’s Malay, Chinese and Indians. Additionally, all females in this study were homozygous for PvuII Type 2 polymorphism. Thus, we concluded that this polymorphism is widespread in all Malaysian population and is not unique to just Africans. However, these findings indicated that the polymorphism was widely conserved and can be used to study the African descendant in any world population hitherto supporting the ‘Out of Africa’ theory.
format	Article
author	Endom Ismail, Farahnaz Amini, Shairah Abdul Razak, Husna Mohd Zaini, Reza Farhour, Bin Alwi Zilfalil,
spellingShingle	Endom Ismail, Farahnaz Amini, Shairah Abdul Razak, Husna Mohd Zaini, Reza Farhour, Bin Alwi Zilfalil, Peninsular Malaysia’s Negrito orang Asli and its theory of African origin
author_facet	Endom Ismail, Farahnaz Amini, Shairah Abdul Razak, Husna Mohd Zaini, Reza Farhour, Bin Alwi Zilfalil,
author_sort	Endom Ismail,
title	Peninsular Malaysia’s Negrito orang Asli and its theory of African origin
title_short	Peninsular Malaysia’s Negrito orang Asli and its theory of African origin
title_full	Peninsular Malaysia’s Negrito orang Asli and its theory of African origin
title_fullStr	Peninsular Malaysia’s Negrito orang Asli and its theory of African origin
title_full_unstemmed	Peninsular Malaysia’s Negrito orang Asli and its theory of African origin
title_sort	peninsular malaysia’s negrito orang asli and its theory of african origin
publisher	Universiti Kebangsaan Malaysia
publishDate	2013
url	http://journalarticle.ukm.my/6298/ http://journalarticle.ukm.my/6298/ http://journalarticle.ukm.my/6298/1/05_Endom_Ismil_.pdf
first_indexed	2023-09-18T19:46:29Z
last_indexed	2023-09-18T19:46:29Z
_version_	1777405934753021952

Peninsular Malaysia’s Negrito orang Asli and its theory of African origin

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