Molecularly imprinted polymer synthesis using RAFT polymerisation

In this paper, the synthesis and characterisation of caffeine-imprinted polymers are described. The polymers were prepared in monolithic form via both reversible addition-fragmentation chain-transfer (RAFT) polymerisation and conventional free radical polymerisation, using methacrylic acid and ethyl...

Full description

Bibliographic Details
Main Authors:	Cormack, Peter A.G., Faizatul Shimal Mehamod
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2013
Online Access:	http://journalarticle.ukm.my/6089/ http://journalarticle.ukm.my/6089/ http://journalarticle.ukm.my/6089/1/15_Peter.pdf

id	ukm-6089
recordtype	eprints
spelling	ukm-60892016-12-14T06:40:20Z http://journalarticle.ukm.my/6089/ Molecularly imprinted polymer synthesis using RAFT polymerisation Cormack, Peter A.G. Faizatul Shimal Mehamod, In this paper, the synthesis and characterisation of caffeine-imprinted polymers are described. The polymers were prepared in monolithic form via both reversible addition-fragmentation chain-transfer (RAFT) polymerisation and conventional free radical polymerisation, using methacrylic acid and ethylene glycol dimethacrylate as the functional monomer and crosslinking agent, respectively. The potential benefits in applying RAFT polymerisation techniques towards the synthesis of molecularly imprinted polymers (MIPs) are explored and elucidated. The pore structures of the polymers produced were characterised by nitrogen sorption porosimetry and the molecular recognition properties of representative products were evaluated in high-performance liquid chromatography (HPLC) mode. Molecular imprinting effects were confirmed by analysing the relative retentions of analytes on imprinted and non-imprinted HPLC stationary phases. It was found that a caffeine-imprinted polymer synthesised by RAFT polymerisation was superior to a polymer prepared using a conventional synthetic approach; the imprinting factor and column efficiency were found to be higher for the former material. Universiti Kebangsaan Malaysia 2013-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/6089/1/15_Peter.pdf Cormack, Peter A.G. and Faizatul Shimal Mehamod, (2013) Molecularly imprinted polymer synthesis using RAFT polymerisation. Sains Malaysiana, 42 (4). pp. 529-535. ISSN 0126-6039 http://www.ukm.my/jsm/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	In this paper, the synthesis and characterisation of caffeine-imprinted polymers are described. The polymers were prepared in monolithic form via both reversible addition-fragmentation chain-transfer (RAFT) polymerisation and conventional free radical polymerisation, using methacrylic acid and ethylene glycol dimethacrylate as the functional monomer and crosslinking agent, respectively. The potential benefits in applying RAFT polymerisation techniques towards the synthesis of molecularly imprinted polymers (MIPs) are explored and elucidated. The pore structures of the polymers produced were characterised by nitrogen sorption porosimetry and the molecular recognition properties of representative products were evaluated in high-performance liquid chromatography (HPLC) mode. Molecular imprinting effects were confirmed by analysing the relative retentions of analytes on imprinted and non-imprinted HPLC stationary phases. It was found that a caffeine-imprinted polymer synthesised by RAFT polymerisation was superior to a polymer prepared using a conventional synthetic approach; the imprinting factor and column efficiency were found to be higher for the former material.
format	Article
author	Cormack, Peter A.G. Faizatul Shimal Mehamod,
spellingShingle	Cormack, Peter A.G. Faizatul Shimal Mehamod, Molecularly imprinted polymer synthesis using RAFT polymerisation
author_facet	Cormack, Peter A.G. Faizatul Shimal Mehamod,
author_sort	Cormack, Peter A.G.
title	Molecularly imprinted polymer synthesis using RAFT polymerisation
title_short	Molecularly imprinted polymer synthesis using RAFT polymerisation
title_full	Molecularly imprinted polymer synthesis using RAFT polymerisation
title_fullStr	Molecularly imprinted polymer synthesis using RAFT polymerisation
title_full_unstemmed	Molecularly imprinted polymer synthesis using RAFT polymerisation
title_sort	molecularly imprinted polymer synthesis using raft polymerisation
publisher	Universiti Kebangsaan Malaysia
publishDate	2013
url	http://journalarticle.ukm.my/6089/ http://journalarticle.ukm.my/6089/ http://journalarticle.ukm.my/6089/1/15_Peter.pdf
first_indexed	2023-09-18T19:45:57Z
last_indexed	2023-09-18T19:45:57Z
_version_	1777405900651233280

Molecularly imprinted polymer synthesis using RAFT polymerisation

Similar Items