Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications

The aim of this study was to observe the pattern of lactate dehydrogenase (LDH) activity in GCF and the rate of tooth movement at two different orthodontic forces (1.0 N and 1.5 N). Twelve subjects participated in this study and was chosen based on the inclusion criteria. Each subject received force...

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Main Authors:	Shahrul Hisham Zainal Ariffin, Nurfathiha Abu Kasim, Rohaya Megat Abdul Wahab, Abdul Aziz Jemain
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2013
Online Access:	http://journalarticle.ukm.my/5712/ http://journalarticle.ukm.my/5712/ http://journalarticle.ukm.my/5712/1/17%2520Shahrul%2520Hisham.pdf

id	ukm-5712
recordtype	eprints
spelling	ukm-57122016-12-14T06:39:16Z http://journalarticle.ukm.my/5712/ Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications Shahrul Hisham Zainal Ariffin, Nurfathiha Abu Kasim, Rohaya Megat Abdul Wahab, Abdul Aziz Jemain, The aim of this study was to observe the pattern of lactate dehydrogenase (LDH) activity in GCF and the rate of tooth movement at two different orthodontic forces (1.0 N and 1.5 N). Twelve subjects participated in this study and was chosen based on the inclusion criteria. Each subject received forces of 1.0 N and 1.5 N for tooth movement either on the left or right side of the maxillary canine. GCF sample was collected at mesial and distal sites of the canines before applying the appliance (week 0) and every week for 5 weeks after tooth movement (week 1 to week 5) where baseline activity served as control. LDH activity was assayed spectrophotometically at 340 nm. The tooth movements were measured from casted study models. LDH specific activity at mesial sites in 1.0 N and 1.5 N force groups, respectively increased significantly (p<0.05) only on week four and throughout the treatment when compared with baseline. At distal sites, LDH specific activity with 1.5 N was higher than 1.0 N throughout the five weeks of tooth movement. LDH specific activity with 1.5 N force increased at both mesial (week 2) and distal sites (week 3) with significant different (p<0.05) when compared with 1.0 N force. Tooth movement with 1.5 N showed significantly faster (p<0.05) at the end of week 5 when compared with 1.0 N. LDH has the potential as a biological marker of inflammation during tooth movement.A force of 1 N was more suitable to be used although less tooth movement was produced because less inflammation caused by the force can be useful in orthodontic treatment for patients with stabilised periodontal diseases compared with 1.5 N force. Universiti Kebangsaan Malaysia 2013-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/5712/1/17%2520Shahrul%2520Hisham.pdf Shahrul Hisham Zainal Ariffin, and Nurfathiha Abu Kasim, and Rohaya Megat Abdul Wahab, and Abdul Aziz Jemain, (2013) Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications. Sains Malaysiana, 42 (1). pp. 99-105. ISSN 0126-6039 http://www.ukm.my/jsm/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	The aim of this study was to observe the pattern of lactate dehydrogenase (LDH) activity in GCF and the rate of tooth movement at two different orthodontic forces (1.0 N and 1.5 N). Twelve subjects participated in this study and was chosen based on the inclusion criteria. Each subject received forces of 1.0 N and 1.5 N for tooth movement either on the left or right side of the maxillary canine. GCF sample was collected at mesial and distal sites of the canines before applying the appliance (week 0) and every week for 5 weeks after tooth movement (week 1 to week 5) where baseline activity served as control. LDH activity was assayed spectrophotometically at 340 nm. The tooth movements were measured from casted study models. LDH specific activity at mesial sites in 1.0 N and 1.5 N force groups, respectively increased significantly (p<0.05) only on week four and throughout the treatment when compared with baseline. At distal sites, LDH specific activity with 1.5 N was higher than 1.0 N throughout the five weeks of tooth movement. LDH specific activity with 1.5 N force increased at both mesial (week 2) and distal sites (week 3) with significant different (p<0.05) when compared with 1.0 N force. Tooth movement with 1.5 N showed significantly faster (p<0.05) at the end of week 5 when compared with 1.0 N. LDH has the potential as a biological marker of inflammation during tooth movement.A force of 1 N was more suitable to be used although less tooth movement was produced because less inflammation caused by the force can be useful in orthodontic treatment for patients with stabilised periodontal diseases compared with 1.5 N force.
format	Article
author	Shahrul Hisham Zainal Ariffin, Nurfathiha Abu Kasim, Rohaya Megat Abdul Wahab, Abdul Aziz Jemain,
spellingShingle	Shahrul Hisham Zainal Ariffin, Nurfathiha Abu Kasim, Rohaya Megat Abdul Wahab, Abdul Aziz Jemain, Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications
author_facet	Shahrul Hisham Zainal Ariffin, Nurfathiha Abu Kasim, Rohaya Megat Abdul Wahab, Abdul Aziz Jemain,
author_sort	Shahrul Hisham Zainal Ariffin,
title	Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications
title_short	Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications
title_full	Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications
title_fullStr	Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications
title_full_unstemmed	Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications
title_sort	lactate dehydrogenase activity during tooth movement under 1.0 n and 1.5 n continuous force applications
publisher	Universiti Kebangsaan Malaysia
publishDate	2013
url	http://journalarticle.ukm.my/5712/ http://journalarticle.ukm.my/5712/ http://journalarticle.ukm.my/5712/1/17%2520Shahrul%2520Hisham.pdf
first_indexed	2023-09-18T19:44:54Z
last_indexed	2023-09-18T19:44:54Z
_version_	1777405834773397504

Lactate dehydrogenase activity during tooth movement under 1.0 N and 1.5 N continuous force applications

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