Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study

The objective of this study was to establish the association of plasma fibronectin in saliva of pregnant women with history of miscarriage(s). A total of 25 pregnant women with history of miscarriage(s) were recruited at the Antenatal Clinic of University Malaya Medical Centre (UMMC), Kuala Lumpur a...

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Main Authors:	Farha Ariffin, Salmah Kamin, Jamiyah Hassan, Haliza Hasan
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2013
Online Access:	http://journalarticle.ukm.my/5701/ http://journalarticle.ukm.my/5701/ http://journalarticle.ukm.my/5701/1/06%2520Farha.pdf

id	ukm-5701
recordtype	eprints
spelling	ukm-57012016-12-14T06:39:14Z http://journalarticle.ukm.my/5701/ Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study Farha Ariffin, Salmah Kamin, Jamiyah Hassan, Haliza Hasan, The objective of this study was to establish the association of plasma fibronectin in saliva of pregnant women with history of miscarriage(s). A total of 25 pregnant women with history of miscarriage(s) were recruited at the Antenatal Clinic of University Malaya Medical Centre (UMMC), Kuala Lumpur as the test group and 16 pregnant women without any history of miscarriage served as control. All the subjects fulfilled a set of inclusion and exclusion criteria. Periodontal examination was performed to determine subjects’ periodontal status. Saliva samples were collected and enzyme-linked immunosorbent assay (ELISA) was used to detect the plasma fibronectin in these samples. Mann-Whitney test was used to determine the significance of differences seen. The study showed a statistically significant higher median plasma fibronectin level in the saliva samples of the test group with a median level of 0.10 μg/mL compared with the control group with a mean value of 0.00 μg/mL (p-value =0.023). However, there was no significant difference in the level of plasma fibronectin in the saliva samples of pregnant women with chronic periodontitis compared with the group with healthy gingiva (p-value= 0.118). As a conclusion, there was a positive association between plasma fibronectin in saliva of women and history of miscarriages compared with the control group in this case study. Universiti Kebangsaan Malaysia 2013-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/5701/1/06%2520Farha.pdf Farha Ariffin, and Salmah Kamin, and Jamiyah Hassan, and Haliza Hasan, (2013) Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study. Sains Malaysiana, 42 (1). pp. 33-38. ISSN 0126-6039 http://www.ukm.my/jsm/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	The objective of this study was to establish the association of plasma fibronectin in saliva of pregnant women with history of miscarriage(s). A total of 25 pregnant women with history of miscarriage(s) were recruited at the Antenatal Clinic of University Malaya Medical Centre (UMMC), Kuala Lumpur as the test group and 16 pregnant women without any history of miscarriage served as control. All the subjects fulfilled a set of inclusion and exclusion criteria. Periodontal examination was performed to determine subjects’ periodontal status. Saliva samples were collected and enzyme-linked immunosorbent assay (ELISA) was used to detect the plasma fibronectin in these samples. Mann-Whitney test was used to determine the significance of differences seen. The study showed a statistically significant higher median plasma fibronectin level in the saliva samples of the test group with a median level of 0.10 μg/mL compared with the control group with a mean value of 0.00 μg/mL (p-value =0.023). However, there was no significant difference in the level of plasma fibronectin in the saliva samples of pregnant women with chronic periodontitis compared with the group with healthy gingiva (p-value= 0.118). As a conclusion, there was a positive association between plasma fibronectin in saliva of women and history of miscarriages compared with the control group in this case study.
format	Article
author	Farha Ariffin, Salmah Kamin, Jamiyah Hassan, Haliza Hasan,
spellingShingle	Farha Ariffin, Salmah Kamin, Jamiyah Hassan, Haliza Hasan, Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
author_facet	Farha Ariffin, Salmah Kamin, Jamiyah Hassan, Haliza Hasan,
author_sort	Farha Ariffin,
title	Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_short	Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_full	Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_fullStr	Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_full_unstemmed	Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_sort	plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
publisher	Universiti Kebangsaan Malaysia
publishDate	2013
url	http://journalarticle.ukm.my/5701/ http://journalarticle.ukm.my/5701/ http://journalarticle.ukm.my/5701/1/06%2520Farha.pdf
first_indexed	2023-09-18T19:44:53Z
last_indexed	2023-09-18T19:44:53Z
_version_	1777405833313779712

Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study

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