Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant.
Inflammatory Pseudotumor (IP) of bladder is one of a variety of lesions which may arise from spindle cell lesions in the bladder. It is benign in nature compared to the other end of the spectrum of spindle cell lesions, such as sarcoma, sarcomatoid carcinoma and leiomyosarcoma. The diagnosis of IP a...
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Department of Surgery, UKM Medical Centre
2012
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ukm-52392016-12-14T06:37:54Z http://journalarticle.ukm.my/5239/ Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. Muhammad Akbar, S, Praveen HCK, Christopher EH, Goh Swaminathan, Zulkifli MZ, Inflammatory Pseudotumor (IP) of bladder is one of a variety of lesions which may arise from spindle cell lesions in the bladder. It is benign in nature compared to the other end of the spectrum of spindle cell lesions, such as sarcoma, sarcomatoid carcinoma and leiomyosarcoma. The diagnosis of IP and its differentiation from a malignant pathology is a diagnostic dilemma for Urologist and Pathologist as both entities share certain similar morphological and histo-pathological appearance as well as immuno-histo chemistry staining. It is however crucial to avoid misdiagnosis as the treatment option varies significantly between a radical or partial cystectomy with future surveillance cystoscopes. Hereby, we highlight a case of a benign variant of spindle cell tumour of bladder which needed second pathology review for confirmation and thus avoiding a radical cystectomy. We also review the literature on its presentation and emphasis characteristics differentiating a benign from a malignant pathology. Department of Surgery, UKM Medical Centre 2012-02-25 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/5239/1/13-MS1046%2846-49%29.pdf Muhammad Akbar, and S, Praveen and HCK, Christopher and EH, Goh and Swaminathan, and Zulkifli MZ, (2012) Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. Journal of Surgical Academia, 2 (1). pp. 46-49. ISSN 2231-7481 http://jsurgacad.com/ |
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Universiti Kebangasaan Malaysia |
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Online Access |
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description |
Inflammatory Pseudotumor (IP) of bladder is one of a variety of lesions which may arise from spindle cell lesions in the bladder. It is benign in nature compared to the other end of the spectrum of spindle cell lesions, such as sarcoma, sarcomatoid carcinoma and leiomyosarcoma. The diagnosis of IP and its differentiation from a malignant pathology is a diagnostic dilemma for Urologist and Pathologist as both entities share certain similar morphological and histo-pathological appearance as well as immuno-histo chemistry staining. It is however crucial to avoid misdiagnosis as the treatment option varies significantly between a radical or partial cystectomy with future surveillance cystoscopes. Hereby, we highlight a case of a benign variant of spindle cell tumour of bladder which needed second pathology review for confirmation and thus avoiding a radical cystectomy. We also review the literature on its presentation and emphasis characteristics differentiating a benign from a malignant pathology. |
format |
Article |
author |
Muhammad Akbar, S, Praveen HCK, Christopher EH, Goh Swaminathan, Zulkifli MZ, |
spellingShingle |
Muhammad Akbar, S, Praveen HCK, Christopher EH, Goh Swaminathan, Zulkifli MZ, Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. |
author_facet |
Muhammad Akbar, S, Praveen HCK, Christopher EH, Goh Swaminathan, Zulkifli MZ, |
author_sort |
Muhammad Akbar, |
title |
Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. |
title_short |
Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. |
title_full |
Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. |
title_fullStr |
Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. |
title_full_unstemmed |
Inflamatory Pseudotumor of the Bladder: A Histopathological Diagnostic Challenge from Its Malignant Variant. |
title_sort |
inflamatory pseudotumor of the bladder: a histopathological diagnostic challenge from its malignant variant. |
publisher |
Department of Surgery, UKM Medical Centre |
publishDate |
2012 |
url |
http://journalarticle.ukm.my/5239/ http://journalarticle.ukm.my/5239/ http://journalarticle.ukm.my/5239/1/13-MS1046%2846-49%29.pdf |
first_indexed |
2023-09-18T19:43:38Z |
last_indexed |
2023-09-18T19:43:38Z |
_version_ |
1777405754924335104 |