Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats

This study evaluated four different doses of Strobilanthes crispa juice (700, 2100, 3500 and 4900 mg kg-1 of body weight) administered orally to normal female and male Sprague dawley rats on possible changes in various physical, behaviour, morphology and biochemical parameter. The rats were treated...

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Main Authors:	Norfarizan-Hanoon, N.A, Asmah, R, Fauziah, O, Rokiah, M.Y, Faridah, H
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2012
Online Access:	http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/1/03%2520N.A.%2520Norfarizan.pdf

id	ukm-3928
recordtype	eprints
spelling	ukm-39282016-12-14T06:35:20Z http://journalarticle.ukm.my/3928/ Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H This study evaluated four different doses of Strobilanthes crispa juice (700, 2100, 3500 and 4900 mg kg-1 of body weight) administered orally to normal female and male Sprague dawley rats on possible changes in various physical, behaviour, morphology and biochemical parameter. The rats were treated with a single dose of juice and observed for 14 days. No significant toxicity was observed with respect to clinical parameters and organ morphology. In addition, no significant changes were observed in the level of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatinine and albumin. The S. crispus juice was found to be safe at the maximum dose used in this study (4900 mg kg-1 of body weight). Universiti Kebangsaan Malaysia 2012-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/3928/1/03%2520N.A.%2520Norfarizan.pdf Norfarizan-Hanoon, N.A and Asmah, R and Fauziah, O and Rokiah, M.Y and Faridah, H (2012) Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats. Sains Malaysiana, 41 (4). pp. 403-409. ISSN 0126-6039 http://www.ukm.my/jsm/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	This study evaluated four different doses of Strobilanthes crispa juice (700, 2100, 3500 and 4900 mg kg-1 of body weight) administered orally to normal female and male Sprague dawley rats on possible changes in various physical, behaviour, morphology and biochemical parameter. The rats were treated with a single dose of juice and observed for 14 days. No significant toxicity was observed with respect to clinical parameters and organ morphology. In addition, no significant changes were observed in the level of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatinine and albumin. The S. crispus juice was found to be safe at the maximum dose used in this study (4900 mg kg-1 of body weight).
format	Article
author	Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H
spellingShingle	Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
author_facet	Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H
author_sort	Norfarizan-Hanoon, N.A
title	Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
title_short	Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
title_full	Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
title_fullStr	Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
title_full_unstemmed	Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
title_sort	absence of toxicity of strobilanthes crispajuice in acute oral toxicity study in sprague dawley rats
publisher	Universiti Kebangsaan Malaysia
publishDate	2012
url	http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/1/03%2520N.A.%2520Norfarizan.pdf
first_indexed	2023-09-18T19:40:08Z
last_indexed	2023-09-18T19:40:08Z
_version_	1777405535284363264

Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats

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