A combined SEM and TEM studies of microsporum canis after in vitro treatment with atratoxin B1 from holothuria atra
Atratoxin B1 which was extracted from a local sea cucumber, Holothuria atra is a potential antifungal agent against dermatophytes. Exposure of Microsporum canis mycelia inoculated into Sabouraud glucose agar medium to the 10 mg/ml atratoxin B1 solution, resulted in complete suppression of the fungal...
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| Format: | Article |
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Universiti Kebangsaan Malaysia
1996
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| Online Access: | http://journalarticle.ukm.my/3682/ http://journalarticle.ukm.my/3682/ |
| Summary: | Atratoxin B1 which was extracted from a local sea cucumber, Holothuria atra is a potential antifungal agent against dermatophytes. Exposure of Microsporum canis mycelia inoculated into Sabouraud glucose agar medium to the 10 mg/ml atratoxin B1 solution, resulted in complete suppression of the fungal growth. Prolonged exposure to the atratoxin B] (72 hours) resulted with necrosis in a substantial portion of the existing hyphae. The main anomalies noted were the abnormally shaped hyphae and the alterations in its morphology and cytology. |
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