Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone

Receiver Operating Characteristic (ROC) Curves are frequently used in biomedical informatics research to evaluate classification and prediction models to support decision, diagnosis, and prognosis. ROC analysis investigates the accuracy of models and has ability to separate positive from negat...

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Main Authors: Tazhibi Mehdi, N, Bashardoost, M, Ahmadi
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2011
Online Access:http://journalarticle.ukm.my/3560/
http://journalarticle.ukm.my/3560/
http://journalarticle.ukm.my/3560/1/special%2520issue%25202011_33.pdf
id ukm-3560
recordtype eprints
spelling ukm-35602016-12-14T06:34:48Z http://journalarticle.ukm.my/3560/ Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone Tazhibi Mehdi, N, Bashardoost M, Ahmadi Receiver Operating Characteristic (ROC) Curves are frequently used in biomedical informatics research to evaluate classification and prediction models to support decision, diagnosis, and prognosis. ROC analysis investigates the accuracy of models and has ability to separate positive from negative cases. It is especially useful in evaluating predictive models and compare to other tests which produce output values in a continuous range. Empirical ROC curve is jagged but a true ROC curve is smooth. For this purpose kernel smoothing were used. The Area Under ROC Curve (AUC) frequently is used as a measure of the effectiveness of diagnostic markers. In this study we compare estimation of this area based on normal assumptions and kernel smoothing. This study used measurements of TSH from patients and non-diseased people of congenital hypothyroidism screening in Isfahan province. Using the method, TSH ROC curves from Isfahani's infants were fitted. For evaluating of accuracy of this test, AUC and its standard error calculated. Also effectiveness of the kernel methods in comparison to other methods showed. Universiti Kebangsaan Malaysia 2011 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/3560/1/special%2520issue%25202011_33.pdf Tazhibi Mehdi, and N, Bashardoost and M, Ahmadi (2011) Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone. International Journal of Public Health Research, Specia . pp. 239-242. ISSN 2232-0245 http://www.ijphr.ukm.my/
repository_type Digital Repository
institution_category Local University
institution Universiti Kebangasaan Malaysia
building UKM Institutional Repository
collection Online Access
language English
description Receiver Operating Characteristic (ROC) Curves are frequently used in biomedical informatics research to evaluate classification and prediction models to support decision, diagnosis, and prognosis. ROC analysis investigates the accuracy of models and has ability to separate positive from negative cases. It is especially useful in evaluating predictive models and compare to other tests which produce output values in a continuous range. Empirical ROC curve is jagged but a true ROC curve is smooth. For this purpose kernel smoothing were used. The Area Under ROC Curve (AUC) frequently is used as a measure of the effectiveness of diagnostic markers. In this study we compare estimation of this area based on normal assumptions and kernel smoothing. This study used measurements of TSH from patients and non-diseased people of congenital hypothyroidism screening in Isfahan province. Using the method, TSH ROC curves from Isfahani's infants were fitted. For evaluating of accuracy of this test, AUC and its standard error calculated. Also effectiveness of the kernel methods in comparison to other methods showed.
format Article
author Tazhibi Mehdi,
N, Bashardoost
M, Ahmadi
spellingShingle Tazhibi Mehdi,
N, Bashardoost
M, Ahmadi
Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone
author_facet Tazhibi Mehdi,
N, Bashardoost
M, Ahmadi
author_sort Tazhibi Mehdi,
title Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone
title_short Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone
title_full Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone
title_fullStr Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone
title_full_unstemmed Kernel smoothing for ROC curve and estimation for thyroid stimulating hormone
title_sort kernel smoothing for roc curve and estimation for thyroid stimulating hormone
publisher Universiti Kebangsaan Malaysia
publishDate 2011
url http://journalarticle.ukm.my/3560/
http://journalarticle.ukm.my/3560/
http://journalarticle.ukm.my/3560/1/special%2520issue%25202011_33.pdf
first_indexed 2023-09-18T19:39:09Z
last_indexed 2023-09-18T19:39:09Z
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