Virulence gene typing of Methicillin-susceptible Staphylococcus aureus (MSSA)isolates in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)

We determined the presence of four virulence genes: (cna, seh, PVL, TSST-1) using multiplex PCR in 880 isolates of methicillin-susceptible Staphylococcus aureus (MSSA) collected from the Universiti Kebangsaan Malaysia Medical Centre (UKMMC) in 2009. We found that 51.59% (454/880) of the strains ha...

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Bibliographic Details
Main Authors: Hassriana Fazilla Sapri, Nurul Azirah Mohamad Sani, Ainihayati Noordin, Hui-min Neoh, Salasawati Hussin
Format: Article
Language:English
Published: UKM Medical Molecular biology Institute, UMBI 2011
Online Access:http://journalarticle.ukm.my/3060/
http://journalarticle.ukm.my/3060/
http://journalarticle.ukm.my/3060/1/2011-1-4.pdf
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Summary:We determined the presence of four virulence genes: (cna, seh, PVL, TSST-1) using multiplex PCR in 880 isolates of methicillin-susceptible Staphylococcus aureus (MSSA) collected from the Universiti Kebangsaan Malaysia Medical Centre (UKMMC) in 2009. We found that 51.59% (454/880) of the strains had cna; 21.82% (192/880) possessed seh; 10.23% (90/880) had PVL and 6.82% (60/880) haboured TSST-1. Although methicillin-susceptible, MSSA carries important virulence genes which could affect patient’s clinical course.