Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage

Bone formation has been associated with the presence of an enzyme called alkaline phosphatase (ALP). This longitudinal study was carried out to observe its activity in gingival crevicular fluid (GCF) during leveling and alignment stage of orthodontic fixed appliance treatment. Fourteen patients betw...

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Main Authors: Asma Alhusna Abang Abdullah, Rohaya Megat Abdul Wahab, Shahrul Hisham Zainal Ariffin
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2011
Online Access:http://journalarticle.ukm.my/2796/
http://journalarticle.ukm.my/2796/
http://journalarticle.ukm.my/2796/1/12_Asma_Alhusna.pdf
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recordtype eprints
spelling ukm-27962016-12-14T06:32:40Z http://journalarticle.ukm.my/2796/ Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage Asma Alhusna Abang Abdullah, Rohaya Megat Abdul Wahab, Shahrul Hisham Zainal Ariffin, Bone formation has been associated with the presence of an enzyme called alkaline phosphatase (ALP). This longitudinal study was carried out to observe its activity in gingival crevicular fluid (GCF) during leveling and alignment stage of orthodontic fixed appliance treatment. Fourteen patients between the ages of 15 and 27 years old with moderate upper labial segment crowding were recruited from postgraduate orthodontic clinic. GCF from mesial and distal sites of upper canines were collected using endodontic paper point before the fixed appliance placement (week 0). The baseline level of ALP (week 0) acted as a control. Samplings of GCF were repeated at 1st, 2nd and 3rd week during orthodontic treatment. The activities of ALP were measured using spectrophotometer (405 nm). Paired sample t-test was used to assess the significance of difference over the 3 weeks. Although the results showed patterns of ALP activities on the test teeth throughout the 3 weeks of leveling and alignment stage, however the results were not significant (p >0.05) when compared to control. Therefore, it has been shown that there was no significant pattern of ALP activities in GCF in patients undergoing leveling and alignment stage of orthodontic treatment. Universiti Kebangsaan Malaysia 2011-10 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/2796/1/12_Asma_Alhusna.pdf Asma Alhusna Abang Abdullah, and Rohaya Megat Abdul Wahab, and Shahrul Hisham Zainal Ariffin, (2011) Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage. Sains Malaysiana, 40 (10). pp. 1147-1151. ISSN 0126-6039 http://www.ukm.my/jsm/contents.html.
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description Bone formation has been associated with the presence of an enzyme called alkaline phosphatase (ALP). This longitudinal study was carried out to observe its activity in gingival crevicular fluid (GCF) during leveling and alignment stage of orthodontic fixed appliance treatment. Fourteen patients between the ages of 15 and 27 years old with moderate upper labial segment crowding were recruited from postgraduate orthodontic clinic. GCF from mesial and distal sites of upper canines were collected using endodontic paper point before the fixed appliance placement (week 0). The baseline level of ALP (week 0) acted as a control. Samplings of GCF were repeated at 1st, 2nd and 3rd week during orthodontic treatment. The activities of ALP were measured using spectrophotometer (405 nm). Paired sample t-test was used to assess the significance of difference over the 3 weeks. Although the results showed patterns of ALP activities on the test teeth throughout the 3 weeks of leveling and alignment stage, however the results were not significant (p >0.05) when compared to control. Therefore, it has been shown that there was no significant pattern of ALP activities in GCF in patients undergoing leveling and alignment stage of orthodontic treatment.
format Article
author Asma Alhusna Abang Abdullah,
Rohaya Megat Abdul Wahab,
Shahrul Hisham Zainal Ariffin,
spellingShingle Asma Alhusna Abang Abdullah,
Rohaya Megat Abdul Wahab,
Shahrul Hisham Zainal Ariffin,
Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
author_facet Asma Alhusna Abang Abdullah,
Rohaya Megat Abdul Wahab,
Shahrul Hisham Zainal Ariffin,
author_sort Asma Alhusna Abang Abdullah,
title Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
title_short Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
title_full Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
title_fullStr Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
title_full_unstemmed Pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
title_sort pattern of crevicular alkaline phosphatase during orthodontic tooth movement: leveling and alignment stage
publisher Universiti Kebangsaan Malaysia
publishDate 2011
url http://journalarticle.ukm.my/2796/
http://journalarticle.ukm.my/2796/
http://journalarticle.ukm.my/2796/1/12_Asma_Alhusna.pdf
first_indexed 2023-09-18T19:37:00Z
last_indexed 2023-09-18T19:37:00Z
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