Primary Thyroid Lymphoma: two different presentations of a rare disease
Primary thyroid lymphoma is a rare disorder accounting for about 2% of all malignant lymphomas and less than 5% of thyroid malignancies. It is an aggressive disease with poor outcome. The majority of thyroid lymphomas are non-Hodgkin lymphomas of Bcell origin. Majority of cases occur in women in...
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| Format: | Article |
| Language: | English |
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Penerbit UKM
2010
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| Online Access: | http://journalarticle.ukm.my/2090/ http://journalarticle.ukm.my/2090/ http://journalarticle.ukm.my/2090/1/08MS090_4144.pdf |
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ukm-20902016-12-14T06:30:51Z http://journalarticle.ukm.my/2090/ Primary Thyroid Lymphoma: two different presentations of a rare disease Azlin I, Leong CF, NH Hamidah, Sharifah NA, Rohaizak M, Primary thyroid lymphoma is a rare disorder accounting for about 2% of all malignant lymphomas and less than 5% of thyroid malignancies. It is an aggressive disease with poor outcome. The majority of thyroid lymphomas are non-Hodgkin lymphomas of Bcell origin. Majority of cases occur in women in the sixth decade. We report two cases of primary thyroid lymphoma and highlight the clinical issues and challenges posed by this rare disease. Both cases presented with respiratory obstructive symptoms that required surgical intervention. The optimal management for a primary thyroid lymphoma be it chemotherapy, radiotherapy, surgery or monoclonal antibodies is still debatable. The role for surgery has evolved through the years but its importance in emergency situations should not be overlooked. Both our patients had to undergo surgery but only one patient received additional chemotherapy and radiotherapy. These two case reports illustrated the difficulties in managing this rare disorder. Penerbit UKM 2010 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/2090/1/08MS090_4144.pdf Azlin I, and Leong CF, and NH Hamidah, and Sharifah NA, and Rohaizak M, (2010) Primary Thyroid Lymphoma: two different presentations of a rare disease. Medicine & Health, 5 (2). pp. 114-119. ISSN 1823-2140 http://www.ppukm.ukm.my/ukmmcjournal/index.php |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
Universiti Kebangasaan Malaysia |
| building |
UKM Institutional Repository |
| collection |
Online Access |
| language |
English |
| description |
Primary thyroid lymphoma is a rare disorder accounting for about 2% of all malignant
lymphomas and less than 5% of thyroid malignancies. It is an aggressive disease with
poor outcome. The majority of thyroid lymphomas are non-Hodgkin lymphomas of Bcell
origin. Majority of cases occur in women in the sixth decade. We report two cases
of primary thyroid lymphoma and highlight the clinical issues and challenges posed by
this rare disease. Both cases presented with respiratory obstructive symptoms that
required surgical intervention. The optimal management for a primary thyroid lymphoma
be it chemotherapy, radiotherapy, surgery or monoclonal antibodies is still debatable.
The role for surgery has evolved through the years but its importance in
emergency situations should not be overlooked. Both our patients had to undergo surgery
but only one patient received additional chemotherapy and radiotherapy. These
two case reports illustrated the difficulties in managing this rare disorder. |
| format |
Article |
| author |
Azlin I, Leong CF, NH Hamidah, Sharifah NA, Rohaizak M, |
| spellingShingle |
Azlin I, Leong CF, NH Hamidah, Sharifah NA, Rohaizak M, Primary Thyroid Lymphoma: two different presentations of a rare disease |
| author_facet |
Azlin I, Leong CF, NH Hamidah, Sharifah NA, Rohaizak M, |
| author_sort |
Azlin I, |
| title |
Primary Thyroid Lymphoma: two different presentations
of a rare disease |
| title_short |
Primary Thyroid Lymphoma: two different presentations
of a rare disease |
| title_full |
Primary Thyroid Lymphoma: two different presentations
of a rare disease |
| title_fullStr |
Primary Thyroid Lymphoma: two different presentations
of a rare disease |
| title_full_unstemmed |
Primary Thyroid Lymphoma: two different presentations
of a rare disease |
| title_sort |
primary thyroid lymphoma: two different presentations
of a rare disease |
| publisher |
Penerbit UKM |
| publishDate |
2010 |
| url |
http://journalarticle.ukm.my/2090/ http://journalarticle.ukm.my/2090/ http://journalarticle.ukm.my/2090/1/08MS090_4144.pdf |
| first_indexed |
2023-09-18T19:35:10Z |
| last_indexed |
2023-09-18T19:35:10Z |
| _version_ |
1777405222831783936 |