Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre
Helicobacter pylori has been implicated as an aetiologic agent for type B chronic gastritis, peptic ulcer and gastric cancer. It is considered the most common bacterial infection in the world with approximately 50% of the population being infected. The majority of infected individuals are asympto...
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2010
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| Online Access: | http://journalarticle.ukm.my/2045/ http://journalarticle.ukm.my/2045/ http://journalarticle.ukm.my/2045/1/04MS102_112.pdf |
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ukm-20452016-12-14T06:30:45Z http://journalarticle.ukm.my/2045/ Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre Alfizah H, Rizal AM, Isa MR, Aminudin A, Jasmi AY, Ramelah M, Helicobacter pylori has been implicated as an aetiologic agent for type B chronic gastritis, peptic ulcer and gastric cancer. It is considered the most common bacterial infection in the world with approximately 50% of the population being infected. The majority of infected individuals are asymptomatic, with some developing gastritis only. However, chronic infection with H. pylori without antibiotic treatment predisposes infected individuals to the development of gastric cancer. The aim of this study is to determine active H. pylori infection among patients with symptoms of dyspepsia using three combinations of diagnostic methods. In this report, we studied 1,376 consecutive patients who underwent upper gastrointestinal endoscopy at Universiti Kebangsaan Malaysia Medical Center (UKMMC) for dyspepsia from the period January 1999 to December 2002. The classification of patient’s diagnosis was assessed by endoscopic and histological examination. The H. pylori status was determined by rapid urease test, histological examination or H. pylori culture. Presence of H. pylori infection was confirmed in 30.8% of patients with dyspepsia. H. pylori infection was more prevalent in older patients and in males compared to females. Patients with severe gastroduodenal diseases were more commonly infected with H. pylori. There was a significant difference in H. pylori prevalence among the different ethnic groups. Indians had the highest infection rate (45.4%), followed by Chinese (36.8%) and the lowest were seen in Malays (18.3%). This finding on determination of active H. pylori infection among patients with dyspepsia is consistent with serological studies that showed racial differences in H. pylori prevalence. However, the pattern of H. pylori infection does not reflect the prevalence of severe gastroduodenal diseases among different ethnic groups. Penerbit UKM 2010 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/2045/1/04MS102_112.pdf Alfizah H, and Rizal AM, and Isa MR, and Aminudin A, and Jasmi AY, and Ramelah M, (2010) Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre. Medicine & Health, 5 (1). pp. 13-21. ISSN 1823-2140 http://www.ppukm.ukm.my/ukmmcjournal/index.php |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
Universiti Kebangasaan Malaysia |
| building |
UKM Institutional Repository |
| collection |
Online Access |
| language |
English |
| description |
Helicobacter pylori has been implicated as an aetiologic agent for type B chronic
gastritis, peptic ulcer and gastric cancer. It is considered the most common bacterial
infection in the world with approximately 50% of the population being infected. The
majority of infected individuals are asymptomatic, with some developing gastritis only.
However, chronic infection with H. pylori without antibiotic treatment predisposes
infected individuals to the development of gastric cancer. The aim of this study is to
determine active H. pylori infection among patients with symptoms of dyspepsia using
three combinations of diagnostic methods. In this report, we studied 1,376 consecutive
patients who underwent upper gastrointestinal endoscopy at Universiti Kebangsaan
Malaysia Medical Center (UKMMC) for dyspepsia from the period January 1999 to
December 2002. The classification of patient’s diagnosis was assessed by endoscopic
and histological examination. The H. pylori status was determined by rapid urease test,
histological examination or H. pylori culture. Presence of H. pylori infection was
confirmed in 30.8% of patients with dyspepsia. H. pylori infection was more prevalent
in older patients and in males compared to females. Patients with severe
gastroduodenal diseases were more commonly infected with H. pylori. There was a
significant difference in H. pylori prevalence among the different ethnic groups.
Indians had the highest infection rate (45.4%), followed by Chinese (36.8%) and the
lowest were seen in Malays (18.3%). This finding on determination of active H. pylori
infection among patients with dyspepsia is consistent with serological studies that
showed racial differences in H. pylori prevalence. However, the pattern of H. pylori
infection does not reflect the prevalence of severe gastroduodenal diseases among
different ethnic groups. |
| format |
Article |
| author |
Alfizah H, Rizal AM, Isa MR, Aminudin A, Jasmi AY, Ramelah M, |
| spellingShingle |
Alfizah H, Rizal AM, Isa MR, Aminudin A, Jasmi AY, Ramelah M, Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre |
| author_facet |
Alfizah H, Rizal AM, Isa MR, Aminudin A, Jasmi AY, Ramelah M, |
| author_sort |
Alfizah H, |
| title |
Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre |
| title_short |
Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre |
| title_full |
Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre |
| title_fullStr |
Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre |
| title_full_unstemmed |
Four years analysis of helicobacter pylori infection among patients with dyspeptic at Universiti Kebangsaan Malaysia Medical Centre |
| title_sort |
four years analysis of helicobacter pylori infection among patients with dyspeptic at universiti kebangsaan malaysia medical centre |
| publisher |
Penerbit UKM |
| publishDate |
2010 |
| url |
http://journalarticle.ukm.my/2045/ http://journalarticle.ukm.my/2045/ http://journalarticle.ukm.my/2045/1/04MS102_112.pdf |
| first_indexed |
2023-09-18T19:35:02Z |
| last_indexed |
2023-09-18T19:35:02Z |
| _version_ |
1777405213757407232 |