A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration

This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol-placebocrystalloid (PC). Ninety patients were included a...

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Main Authors:	Muhd Helmi Azmi, Karis Misiran
Format:	Article
Language:	English
Published:	Penerbit UKM 2007
Online Access:	http://journalarticle.ukm.my/1976/ http://journalarticle.ukm.my/1976/ http://journalarticle.ukm.my/1976/1/Page_103-109__MH_043.pdf

id	ukm-1976
recordtype	eprints
spelling	ukm-19762016-12-14T06:30:33Z http://journalarticle.ukm.my/1976/ A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration Muhd Helmi Azmi, Karis Misiran, This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol-placebocrystalloid (PC). Ninety patients were included and randomly allocated to receive one of the three combinations. The patients were induced using fentanyl 2 μg/kg, followed by propofol 2.5 mg/kg with normal saline as placebo (Group PP and Group PC) or ephedrine 70 μg/kg (Group PE) given over 30 seconds. Subsequently, rocuronium 0.6 mg/kg was given over five seconds and endotracheal intubations were performed 60 seconds later. Intubating conditions were clinically acceptable in all patients except in four patients in PP group, who had poor intubating conditions. The proportion of excellent intubating conditions was significantly highest in Group PE (94%) followed by Group PC (81%) and lowest in Group PP (50%). In conclusion, induction with propofol-ephedrine and propofol-placebo-crystalloid combinations provided significantly better intubating conditions than propofol alone, when rocuronium 0.6 mg/kg was used for intubation at 60 seconds Penerbit UKM 2007 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1976/1/Page_103-109__MH_043.pdf Muhd Helmi Azmi, and Karis Misiran, (2007) A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration. Medicine & Health, 2 (2). pp. 103-109. ISSN 1823-2140 http://www.ppukm.ukm.my/ukmmcjournal/index.php
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol-placebocrystalloid (PC). Ninety patients were included and randomly allocated to receive one of the three combinations. The patients were induced using fentanyl 2 μg/kg, followed by propofol 2.5 mg/kg with normal saline as placebo (Group PP and Group PC) or ephedrine 70 μg/kg (Group PE) given over 30 seconds. Subsequently, rocuronium 0.6 mg/kg was given over five seconds and endotracheal intubations were performed 60 seconds later. Intubating conditions were clinically acceptable in all patients except in four patients in PP group, who had poor intubating conditions. The proportion of excellent intubating conditions was significantly highest in Group PE (94%) followed by Group PC (81%) and lowest in Group PP (50%). In conclusion, induction with propofol-ephedrine and propofol-placebo-crystalloid combinations provided significantly better intubating conditions than propofol alone, when rocuronium 0.6 mg/kg was used for intubation at 60 seconds
format	Article
author	Muhd Helmi Azmi, Karis Misiran,
spellingShingle	Muhd Helmi Azmi, Karis Misiran, A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration
author_facet	Muhd Helmi Azmi, Karis Misiran,
author_sort	Muhd Helmi Azmi,
title	A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration
title_short	A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration
title_full	A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration
title_fullStr	A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration
title_full_unstemmed	A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration
title_sort	comparative study of different induction techniques (propofol-placebo, propofol-ephedrine and propofol- placebo-crystalloid) on intubating conditions after rocuronium administration
publisher	Penerbit UKM
publishDate	2007
url	http://journalarticle.ukm.my/1976/ http://journalarticle.ukm.my/1976/ http://journalarticle.ukm.my/1976/1/Page_103-109__MH_043.pdf
first_indexed	2023-09-18T19:34:53Z
last_indexed	2023-09-18T19:34:53Z
_version_	1777405204298203136

A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration

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