Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia

Thyroid nodules are common but thyroid malignancies are not. Fine needle aspiration (FNA) cytology is a diagnostic tool used to screen patients with thyroid nodules who require surgery. We study the diagnostic accuracy of FNA as the initial diagnostic modality in the clinical assessment of thyroid n...

Full description

Bibliographic Details
Main Authors: Nurismah MI, Sharifah NA, Usama AE, Naqiyah I, Rohaizak M, Jasmi A
Format: Article
Language:English
Published: Penerbit UKM 2007
Online Access:http://journalarticle.ukm.my/1934/
http://journalarticle.ukm.my/1934/
http://journalarticle.ukm.my/1934/1/06._58-65_%28MH_033%29.pdf
id ukm-1934
recordtype eprints
spelling ukm-19342016-12-14T06:30:28Z http://journalarticle.ukm.my/1934/ Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia Nurismah MI, Sharifah NA, Usama AE, Naqiyah I, Rohaizak M, Jasmi A, Thyroid nodules are common but thyroid malignancies are not. Fine needle aspiration (FNA) cytology is a diagnostic tool used to screen patients with thyroid nodules who require surgery. We study the diagnostic accuracy of FNA as the initial diagnostic modality in the clinical assessment of thyroid nodules. Between January 1995 until December 2000, 2131 FNA of thyroid nodules were performed. Four hundred and forty-one (20.7%) of these were unsatisfactory and 1690 (79.3%) cases were satisfactory for cytological evaluation. Histopathological diagnosis were available for 361 cases. Cyto-histopathological correlation was carried out for these cases. Our results showed a diagnostic accuracy of 96.2% with sensitivity and specificity rates of 87.7% and 98.4% respectively. Our positive predictive value is 93.4% and our negative predictive value is 96.8%. From this study, we conclude that fine needle aspiration is an important initial screening diagnostic tool for the investigation of thyroid nodules Penerbit UKM 2007 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1934/1/06._58-65_%28MH_033%29.pdf Nurismah MI, and Sharifah NA, and Usama AE, and Naqiyah I, and Rohaizak M, and Jasmi A, (2007) Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia. Medicine & Health, 2 (1). pp. 58-65. ISSN 1823-2140 http://www.ppukm.ukm.my/ukmmcjournal/index.php
repository_type Digital Repository
institution_category Local University
institution Universiti Kebangasaan Malaysia
building UKM Institutional Repository
collection Online Access
language English
description Thyroid nodules are common but thyroid malignancies are not. Fine needle aspiration (FNA) cytology is a diagnostic tool used to screen patients with thyroid nodules who require surgery. We study the diagnostic accuracy of FNA as the initial diagnostic modality in the clinical assessment of thyroid nodules. Between January 1995 until December 2000, 2131 FNA of thyroid nodules were performed. Four hundred and forty-one (20.7%) of these were unsatisfactory and 1690 (79.3%) cases were satisfactory for cytological evaluation. Histopathological diagnosis were available for 361 cases. Cyto-histopathological correlation was carried out for these cases. Our results showed a diagnostic accuracy of 96.2% with sensitivity and specificity rates of 87.7% and 98.4% respectively. Our positive predictive value is 93.4% and our negative predictive value is 96.8%. From this study, we conclude that fine needle aspiration is an important initial screening diagnostic tool for the investigation of thyroid nodules
format Article
author Nurismah MI,
Sharifah NA,
Usama AE,
Naqiyah I,
Rohaizak M,
Jasmi A,
spellingShingle Nurismah MI,
Sharifah NA,
Usama AE,
Naqiyah I,
Rohaizak M,
Jasmi A,
Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia
author_facet Nurismah MI,
Sharifah NA,
Usama AE,
Naqiyah I,
Rohaizak M,
Jasmi A,
author_sort Nurismah MI,
title Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia
title_short Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia
title_full Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia
title_fullStr Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia
title_full_unstemmed Fine Needle Aspiration (FNA) cytology of the thyroid: A Cyto-Histopathological study of 361 cases in Hospital Universiti Kebangsaan Malaysia
title_sort fine needle aspiration (fna) cytology of the thyroid: a cyto-histopathological study of 361 cases in hospital universiti kebangsaan malaysia
publisher Penerbit UKM
publishDate 2007
url http://journalarticle.ukm.my/1934/
http://journalarticle.ukm.my/1934/
http://journalarticle.ukm.my/1934/1/06._58-65_%28MH_033%29.pdf
first_indexed 2023-09-18T19:34:44Z
last_indexed 2023-09-18T19:34:44Z
_version_ 1777405195260526592