Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts

Scurrula ferruginea is a type of mistletoe from the Loranthaceae family found in Southeast Asia and distributed in tropical regions, is known to have healing effects for many disorders. Preservation of the bioactive metabolites is dependent on the sample preparation and drying methods as well as ext...

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Main Authors:	Vanielie Terrence Justine, Muskhazli Mustafa, Kankara, Sulaiman S., Rusea Go
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:	http://journalarticle.ukm.my/13732/ http://journalarticle.ukm.my/13732/ http://journalarticle.ukm.my/13732/1/07%20Vanielie%20Terrence%20Justine.pdf

id	ukm-13732
recordtype	eprints
spelling	ukm-137322019-11-29T09:13:32Z http://journalarticle.ukm.my/13732/ Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts Vanielie Terrence Justine, Muskhazli Mustafa, Kankara, Sulaiman S. Rusea Go, Scurrula ferruginea is a type of mistletoe from the Loranthaceae family found in Southeast Asia and distributed in tropical regions, is known to have healing effects for many disorders. Preservation of the bioactive metabolites is dependent on the sample preparation and drying methods as well as extraction solvents used. Thus, the present study was carried out to investigate the effect of different drying methods and extraction solvents on the total phenolic and the antioxidant activities of S. ferruginea leaves. The leaves of S. ferruginea were air and oven (60°C) dried and extracted with aqueous, organic and aqueous-organic solvents. The total phenolic content (TPC) and total flavonoid content (TFC) were used to gauge the phenolic antioxidants extracted, while the antioxidant activity was evaluated by measuring the scavenging effect on 2,2- diphenyl-1-picrylhydrazyl (DPPH) radical and via the ferric reducing antioxidant power (FRAP) assay. The optimum conditions obtained were oven drying, 80% acetone with values of 3.47 mg/10 g DW (extract yield), 171.29 mg GAE/1 g DW (TPC), 31.91 mg QE/1 g DW (TFC), 93.2% (DPPH), 26.41 mg TE/1 g DW (FRAP) and 7.41 μg/mL (IC50). The present findings suggested that sample preparation variability using different drying methods and solvents for extraction play a crucial role in enhancing the efficiency of extraction and efficacy of the antioxidant compounds in S. ferruginea leaf extracts. Penerbit Universiti Kebangsaan Malaysia 2019-07 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/13732/1/07%20Vanielie%20Terrence%20Justine.pdf Vanielie Terrence Justine, and Muskhazli Mustafa, and Kankara, Sulaiman S. and Rusea Go, (2019) Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts. Sains Malaysiana, 48 (7). pp. 1383-1393. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid48bil7_2019/KandunganJilid48Bil7_2019.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Scurrula ferruginea is a type of mistletoe from the Loranthaceae family found in Southeast Asia and distributed in tropical regions, is known to have healing effects for many disorders. Preservation of the bioactive metabolites is dependent on the sample preparation and drying methods as well as extraction solvents used. Thus, the present study was carried out to investigate the effect of different drying methods and extraction solvents on the total phenolic and the antioxidant activities of S. ferruginea leaves. The leaves of S. ferruginea were air and oven (60°C) dried and extracted with aqueous, organic and aqueous-organic solvents. The total phenolic content (TPC) and total flavonoid content (TFC) were used to gauge the phenolic antioxidants extracted, while the antioxidant activity was evaluated by measuring the scavenging effect on 2,2- diphenyl-1-picrylhydrazyl (DPPH) radical and via the ferric reducing antioxidant power (FRAP) assay. The optimum conditions obtained were oven drying, 80% acetone with values of 3.47 mg/10 g DW (extract yield), 171.29 mg GAE/1 g DW (TPC), 31.91 mg QE/1 g DW (TFC), 93.2% (DPPH), 26.41 mg TE/1 g DW (FRAP) and 7.41 μg/mL (IC50). The present findings suggested that sample preparation variability using different drying methods and solvents for extraction play a crucial role in enhancing the efficiency of extraction and efficacy of the antioxidant compounds in S. ferruginea leaf extracts.
format	Article
author	Vanielie Terrence Justine, Muskhazli Mustafa, Kankara, Sulaiman S. Rusea Go,
spellingShingle	Vanielie Terrence Justine, Muskhazli Mustafa, Kankara, Sulaiman S. Rusea Go, Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts
author_facet	Vanielie Terrence Justine, Muskhazli Mustafa, Kankara, Sulaiman S. Rusea Go,
author_sort	Vanielie Terrence Justine,
title	Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts
title_short	Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts
title_full	Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts
title_fullStr	Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts
title_full_unstemmed	Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts
title_sort	effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of scurrula ferruginea (jack) danser (loranthaceae) leaf extracts
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2019
url	http://journalarticle.ukm.my/13732/ http://journalarticle.ukm.my/13732/ http://journalarticle.ukm.my/13732/1/07%20Vanielie%20Terrence%20Justine.pdf
first_indexed	2023-09-18T20:05:31Z
last_indexed	2023-09-18T20:05:31Z
_version_	1777407131489665024

Effect of drying methods and extraction solvents on phenolic antioxidants and antioxidant activity of Scurrula ferruginea (Jack) danser (Loranthaceae) leaf extracts

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