Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty

Piper aduncum essential oil exhibit repellency activity and has a potential to be use as an alternative for synthetic repellent such as N,N-diethyl-3- methylbenzamide, (DEET). However, the volatility properties of the essential oil decrease their persistence as a topical repellent. Study has shown t...

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Main Authors:	Hidayatulfathi Othman, Mamood S. N. H., Kalaivany M., Budin S. B., Ahmad Rohi Ghazali, Zulfakar M. H.
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:	http://journalarticle.ukm.my/13332/ http://journalarticle.ukm.my/13332/ http://journalarticle.ukm.my/13332/1/16843-92184-1-PB.pdf

id	ukm-13332
recordtype	eprints
spelling	ukm-133322019-09-06T21:59:56Z http://journalarticle.ukm.my/13332/ Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty Hidayatulfathi Othman, Mamood S. N. H., Kalaivany M., Budin S. B., Ahmad Rohi Ghazali, Zulfakar M. H., Piper aduncum essential oil exhibit repellency activity and has a potential to be use as an alternative for synthetic repellent such as N,N-diethyl-3- methylbenzamide, (DEET). However, the volatility properties of the essential oil decrease their persistence as a topical repellent. Study has shown that formulation of the essential oil with some fixatives may increase their effectiveness. Therefore, this study was conduct to evaluate the effectiveness of gel formulation containing P. aduncum essential oil with two fixative; vanillin and paraffin oil. Gel formulations containing P. aduncum essential oil with 5% and 10% vanillin and 6% paraffin oil was prepared and tested against Aedes aegypti in laboratory using Standards and Industrial Research Institute of Malaysia (SIRIM) bioassay method. After 240 minute post-application, formulation containing 5% and 10% vanillin was able to provide >70% repellency percentage against mosquito while formulation containing 6% paraffin oil gives <30% repellency percentage. As conclusion, P. aduncum based repellent gel containing 5% and 10% vanillin was able to prolong the effect of P. aduncum essential oil as repellent against dengue vector in laboratory. Penerbit Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/13332/1/16843-92184-1-PB.pdf Hidayatulfathi Othman, and Mamood S. N. H., and Kalaivany M., and Budin S. B., and Ahmad Rohi Ghazali, and Zulfakar M. H., (2019) Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty. Jurnal Sains Kesihatan Malaysia, 17 (1). pp. 9-15. ISSN 1675-8161 http://ejournal.ukm.my/jskm/issue/view/686
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Piper aduncum essential oil exhibit repellency activity and has a potential to be use as an alternative for synthetic repellent such as N,N-diethyl-3- methylbenzamide, (DEET). However, the volatility properties of the essential oil decrease their persistence as a topical repellent. Study has shown that formulation of the essential oil with some fixatives may increase their effectiveness. Therefore, this study was conduct to evaluate the effectiveness of gel formulation containing P. aduncum essential oil with two fixative; vanillin and paraffin oil. Gel formulations containing P. aduncum essential oil with 5% and 10% vanillin and 6% paraffin oil was prepared and tested against Aedes aegypti in laboratory using Standards and Industrial Research Institute of Malaysia (SIRIM) bioassay method. After 240 minute post-application, formulation containing 5% and 10% vanillin was able to provide >70% repellency percentage against mosquito while formulation containing 6% paraffin oil gives <30% repellency percentage. As conclusion, P. aduncum based repellent gel containing 5% and 10% vanillin was able to prolong the effect of P. aduncum essential oil as repellent against dengue vector in laboratory.
format	Article
author	Hidayatulfathi Othman, Mamood S. N. H., Kalaivany M., Budin S. B., Ahmad Rohi Ghazali, Zulfakar M. H.,
spellingShingle	Hidayatulfathi Othman, Mamood S. N. H., Kalaivany M., Budin S. B., Ahmad Rohi Ghazali, Zulfakar M. H., Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty
author_facet	Hidayatulfathi Othman, Mamood S. N. H., Kalaivany M., Budin S. B., Ahmad Rohi Ghazali, Zulfakar M. H.,
author_sort	Hidayatulfathi Othman,
title	Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty
title_short	Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty
title_full	Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty
title_fullStr	Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty
title_full_unstemmed	Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty
title_sort	fixatives increase the efficacy of gel formulations containing piper aduncum linnaeus (piperales: piperaceae) essential oil as repellenty
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2019
url	http://journalarticle.ukm.my/13332/ http://journalarticle.ukm.my/13332/ http://journalarticle.ukm.my/13332/1/16843-92184-1-PB.pdf
first_indexed	2023-09-18T20:04:37Z
last_indexed	2023-09-18T20:04:37Z
_version_	1777407075218882560

Fixatives increase the efficacy of gel formulations containing Piper aduncum linnaeus (Piperales: Piperaceae) essential oil as repellenty

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